TOP TEN perturbations for 39278_at (Homo sapiens)
Organism: Homo sapiens
Gene: 39278_at
Selected probe(set): 217566_s_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 39278_at (217566_s_at) across 6674 perturbations tested by GENEVESTIGATOR:
prostate cancer study 1 (meta.) / benign prostate tissue
Relative Expression (log2-ratio):-7.4338636Number of Samples:6 / 6
| Experimental | prostate cancer study 1 (meta.) |
| Metastatic prostate cancer samples. | |
| Control | benign prostate tissue |
| Benign prostate samples. |
prostate cancer study 8 (tissue) / adjacent prostate tissue
Relative Expression (log2-ratio):-6.3306246Number of Samples:5 / 5
| Experimental | prostate cancer study 8 (tissue) |
| Tumor tissue samples from patients with primary prostate cancer collected after radical prostatectomy. | |
| Control | adjacent prostate tissue |
| Histologically normal prostate tissue samples from patients with primary prostate cancer collected after radical prostatectomy. |
prostate cancer study 1 (prim.) / benign prostate tissue
Relative Expression (log2-ratio):-4.9446535Number of Samples:7 / 6
| Experimental | prostate cancer study 1 (prim.) |
| Primary prostate cancer samples. | |
| Control | benign prostate tissue |
| Benign prostate samples. |
vegetable diet 2 (late) / benign prostatic hyperplasia study 1
Relative Expression (log2-ratio):4.2885685Number of Samples:10 / 18
| Experimental | vegetable diet 2 (late) |
| Needle biopsy samples of prostate tissue were obtained by Trans Rectal Ultrasound (TRUS) guided endoscopy from patients with high-grade prostatic intraepithelial neoplasia. Sample biopsies were taken 12 months after the patients were allocated into a 12-month dietary consuming 400g high glucosinolate broccoli per week. High contain glucosinolates containing foods were avoided 48 hours prior biopsy. | |
| Control | benign prostatic hyperplasia study 1 |
| Prostate tissue samples obtained by Trans Urethral Resection of the Prostate (TURP) biopsies from patients with benign prostatic hyperplasia (BIN). |
prostate cancer study 2 / normal prostate gland tissue
Relative Expression (log2-ratio):-3.9203901Number of Samples:17 / 7
| Experimental | prostate cancer study 2 |
| Prostate gland tissue from prostate cancer patients. | |
| Control | normal prostate gland tissue |
| Normal prostate gland tissue. |
vegetable diet study 1 (baseline) / benign prostatic hyperplasia study 1
Relative Expression (log2-ratio):3.0639591Number of Samples:10 / 18
| Experimental | vegetable diet study 1 (baseline) |
| Needle biopsy samples of prostate tissue were obtained by Trans Rectal Ultrasound (TRUS) guided endoscopy from patients with high-grade prostatic intraepithelial neoplasia. Sample biopsies were taken as baseline value before the patients were allocated into a 12-month, parallel dietary divided into two groups consuming 400g high glucosinolate broccoli or 400g low glucosinate per week. | |
| Control | benign prostatic hyperplasia study 1 |
| Prostate tissue samples obtained by Trans Urethral Resection of the Prostate (TURP) biopsies from patients with benign prostatic hyperplasia (BIN). |
vegetable diet 3 (early) / vegetable diet 2 (early)
Relative Expression (log2-ratio):2.8687305Number of Samples:8 / 14
| Experimental | vegetable diet 3 (early) |
| Needle biopsy samples of prostate tissue were obtained by Trans Rectal Ultrasound (TRUS) guided endoscopy from patients with high-grade prostatic intraepithelial neoplasia. Sample biopsies were taken 6 months after the patients were allocated into a 12-month dietary consuming low glucosinolate peas per week. High contain glucosinolates containing foods were avoided 48 hours prior biopsy. | |
| Control | vegetable diet 2 (early) |
| Needle biopsy samples of prostate tissue were obtained by Trans Rectal Ultrasound (TRUS) guided endoscopy from patients with high-grade prostatic intraepithelial neoplasia. Sample biopsies were taken 6 months after the patients were allocated into a 12-month dietary consuming 400g high glucosinolate broccoli per week. High contain glucosinolates containing foods were avoided 48 hours prior biopsy. |
prostate cancer study 1 (meta.) / prostate cancer study 1 (prim.)
Relative Expression (log2-ratio):-2.4892101Number of Samples:6 / 7
| Experimental | prostate cancer study 1 (meta.) |
| Metastatic prostate cancer samples. | |
| Control | prostate cancer study 1 (prim.) |
| Primary prostate cancer samples. |
vegetable diet 2 (early) / benign prostatic hyperplasia study 1
Relative Expression (log2-ratio):2.4438362Number of Samples:14 / 18
| Experimental | vegetable diet 2 (early) |
| Needle biopsy samples of prostate tissue were obtained by Trans Rectal Ultrasound (TRUS) guided endoscopy from patients with high-grade prostatic intraepithelial neoplasia. Sample biopsies were taken 6 months after the patients were allocated into a 12-month dietary consuming 400g high glucosinolate broccoli per week. High contain glucosinolates containing foods were avoided 48 hours prior biopsy. | |
| Control | benign prostatic hyperplasia study 1 |
| Prostate tissue samples obtained by Trans Urethral Resection of the Prostate (TURP) biopsies from patients with benign prostatic hyperplasia (BIN). |
ovarian tumor study 16 / normal ovarian surface epithelial cell sample
Relative Expression (log2-ratio):1.2584362Number of Samples:3 / 5
| Experimental | ovarian tumor study 16 |
| Human epithelial tumor cell samples from the ovary of patients with papillary serous carcinoma. Samples were derived by laser capture microdissection (LCM). | |
| Control | normal ovarian surface epithelial cell sample |
| Human epithelial cell samples from histopathological normal and non-cancerous ovary tissue. |