Organism: Homo sapiens
Gene: 39339_at
Selected probe(set): 202699_s_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 39339_at (202699_s_at) across 6674 perturbations tested by GENEVESTIGATOR:

Relative Expression (log2-ratio):-2.8845968
Number of Samples:2 / 2

Experimental	T-cell activation study 1
	CD4+ T-cell samples derived from PBMC´s of HIV-seronegative donors were activated with plate bound CD3 (1ug/ml) and soluble CD28 (50ng/ml) for 1 day.
Control	quiescent CD4+ T-cell sample
	Quiescent CD4+ T-cell samples derived from PBMC´s of HIV-seronegative donors.

Relative Expression (log2-ratio):-2.5936975
Number of Samples:7 / 2

Experimental	glioma study 16 (oligodendroglioma)
	Primary oligodendroglioma tissues obtained from the operating room. Tumors were diagnosed and graded according to the current WHO classification (grade OGII-III).
Control	normal brain tissue
	Normal brain tissue sample from healthy donors.

Relative Expression (log2-ratio):-2.5327215
Number of Samples:2 / 2

Experimental	T-cell activation study 3
	CD4+ T-cell samples prepared from crude lymphocyte fraction. Cells were activated with anti-CD3/28 beads for 18hrs.
Control	resting CD4 T-lymphocyte (crude fraction) sample
	Resting CD4 T-lymphocytes prepared from crude lymphocyte fraction.

Relative Expression (log2-ratio):-2.4853067
Number of Samples:3 / 2

Experimental	glioma study 16 (secondary glioblastoma)
	Secondary glioma tissues obtained from the operating room. Tumors were diagnosed and graded according to the current WHO classification (grade IV).
Control	normal brain tissue
	Normal brain tissue sample from healthy donors.

Relative Expression (log2-ratio):-2.4677029
Number of Samples:2 / 2

Experimental	Treg activation study 1 (300min)
	Regulatory T-cells were stimulated for 300min with anti-CD3/anti-CD28/IL-2 (100U/ml). Treg were sorted as CD4+ CD25high cells from peripheral blood of healthy donors.
Control	unstimulated regulatory T-cell sample
	Unstimulated regulatory T-cell sample derived from sorted CD4+ CD25high cells from peripheral blood of healthy donors.

Relative Expression (log2-ratio):-2.3823633
Number of Samples:2 / 2

Experimental	T-cell activation study 2
	CD4+ T-cell samples derived from PBMC´s of HIV-seronegative donors were activated with plate bound CD3 (1ug/ml) and soluble CD28 (50ng/ml) for 2 days..
Control	quiescent CD4+ T-cell sample
	Quiescent CD4+ T-cell samples derived from PBMC´s of HIV-seronegative donors.

Relative Expression (log2-ratio):-2.325427
Number of Samples:7 / 3

Experimental	Langerhans cell histiocytosis study 1
	Langerhans cell histiocytes (LCH) were isolated from LCH lesions of patients undergoing surgery. All patients had single system disease, five patients had bone lesion, one had skin lesion and one had mucosal manifestation. Langerhans cells histiocytes were purified by FACS as CD1a+ / CD270 + population with > 95% purity.
Control	normal plasmocytoid dendritic cell sample
	Normal plasmocytoid dendritic cells were isolated from peripheral blood of healthy adult donors. Plasmocytoid dendritic cells were defined as HLA-DR+ / CD45RAhi / CD11c- / BDCA2+ population.

Relative Expression (log2-ratio):2.1990995
Number of Samples:2 / 3

Experimental	glioma study 16 (LN-18)
	Human glioma cell line LN018 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37C and 5% CO2.
Control	normal astrocyte sample
	Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations.

Relative Expression (log2-ratio):-2.1630545
Number of Samples:8 / 2

Experimental	glioma study 16 (astrocytoma)
	Primary astrocytoma tissues obtained from the operating room. Tumors were diagnosed and graded according to the current WHO classification (grade III-IV).
Control	normal brain tissue
	Normal brain tissue sample from healthy donors.

Relative Expression (log2-ratio):-2.1514158
Number of Samples:8 / 8

Experimental	PMA; ionomycine study 2
	CD4+ memory T cells derived from peripheral blood of healthy subjects were stimulated for 3 hours with phorbol 12-myristate 13-acetate (PMA, 10 ng/ml) and ionomycin (1 µg/ml). ATC code:---
Control	unstimulated CD4 memory T-cell sample
	Unstimulated CD4+ memory T cells derived from peripheral blood of healthy subjects.