Organism: Homo sapiens
Gene: 39346_at
Selected probe(set): 200040_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 39346_at (200040_at) across 6674 perturbations tested by GENEVESTIGATOR:

Relative Expression (log2-ratio):-1.9889698
Number of Samples:2 / 2

Experimental	zalypsis study 2
	OPM1 multiple myeloma cells treated in vitro with zalypsis (5 nM), a novel marine-derived compound with potent antimyeloma activity. Cells were harvested at the beginning of induction of cell death (15-20% cell death as assessed by Annexin V-FITC staining). ATC code:---
Control	untreated OPM1 cell sample
	OPM1 multiple myeloma cells untreated.

Relative Expression (log2-ratio):-1.6380405
Number of Samples:5 / 3

Experimental	myotonic dystrophy study 4 (skeletal muscle; DM1)
	Unspecified skeletal muscle biopsies obtained from patients with myotonic dystrophy type 1 (DM1).
Control	normal skeletal muscle tisuue (fetal)
	Commercially purchased normal fetal skeletal muscle tissue samples.

Relative Expression (log2-ratio):-1.5904589
Number of Samples:3 / 3

Experimental	sirolimus study 6 (light)
	Human fetal lung fibroblast cell line (MRC5) treated for 50 minutes with sirolimus (100 nM; vendor: LC laboratories / catalog name: rapamycin). Cells in the growing phase (at 60% confluency) were hypertonically shocked by changing the condition media to a 300 mM NaCl containing Medium for 30 minutes. After hypertonic shock cells were transferred back to isotonic conditions for additional 30 min. Rapamycin was added to the cells during hypertonic shock until the end of recovery (50 minutes total exposure). After treatment RNA was isolated from the light polysome fraction. ATC code:
Control	sirolimus study 6 (heavy)
	Human fetal lung fibroblast cell line (MRC5) treated for 50 minutes with sirolimus (100 nM; vendor: LC laboratories / catalog name: rapamycin). Cells in the growing phase (at 60% confluency) were hypertonically shocked by changing the condition media to a 300 mM NaCl containing Medium for 30 minutes. After hypertonic shock cells were transferred back to isotonic conditions for additional 30 min. Rapamycin was added to the cells during hypertonic shock until the end of recovery (50 minutes total exposure). After treatment RNA was isolated from the heavy polysome fraction. ATC code:

Relative Expression (log2-ratio):-1.5230675
Number of Samples:8 / 3

Experimental	myotonic dystrophy study 4 (skeletal muscle; DM2)
	Unspecified skeletal muscle biopsies obtained from patients with myotonic dystrophy type 2 (DM2).
Control	normal skeletal muscle tisuue (fetal)
	Commercially purchased normal fetal skeletal muscle tissue samples.

Relative Expression (log2-ratio):-1.5163174
Number of Samples:2 / 2

Experimental	theophylline study 5 (10000uM)
	Hepatocytes treated with compound: theophylline (10000uM; CHEMBL190) for 24 hours. ATC code:
Control	vehicle (medium) treated hepatocyte sample
	Hepatocytes treated with vehicle (medium) for 24 hours.

Relative Expression (log2-ratio):-1.4845695
Number of Samples:3 / 3

Experimental	myotonic dystrophy study 4 (deltoid muscle; DM-like)
	Deltoid muscle biopsies obtained from patients with myotonic-like dystrophy (DMx; DM-like; no DMPK or ZNF9 expansion).
Control	normal skeletal muscle tisuue (fetal)
	Commercially purchased normal fetal skeletal muscle tissue samples.

Relative Expression (log2-ratio):-1.4399261
Number of Samples:18 / 12

Experimental	ovarian tumor study 13
	Human epithelial tumor cell samples from the ovary of patients with serous adenocarcinoma. Samples were derived by laser capture microdissection (LCM).
Control	normal ovarian surface epithelial cell sample
	Human epithelial cell samples from histopathological normal and non-cancerous ovary tissue from healthy donors. Samples were derived by cell surface brushing.

Relative Expression (log2-ratio):1.433878
Number of Samples:12 / 5

Experimental	hepatoblastoma study 1 (epithelial mixed)
	Liver tumor tissue samples from children with hepatoblastoma (epithelial type (E-HB); epithelial mixed subtype). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group.
Control	normal liver tissue
	Normal liver tissue samples.

Relative Expression (log2-ratio):-1.4253654
Number of Samples:3 / 3

Experimental	myotonic dystrophy study 4 (deltoid muscle; DM2)
	Deltoid muscle biopsies obtained from patients with myotonic dystrophy type 2 (DM2).
Control	normal skeletal muscle tisuue (fetal)
	Commercially purchased normal fetal skeletal muscle tissue samples.

Relative Expression (log2-ratio):-1.4205294
Number of Samples:3 / 3

Experimental	myotonic dystrophy study 4 (biceps brachii; DM2)
	Biceps brachii biopsies obtained from patients with myotonic dystrophy type 2 (DM2).
Control	normal skeletal muscle tisuue (fetal)
	Commercially purchased normal fetal skeletal muscle tissue samples.