TOP TEN perturbations for 39361_f_at (Homo sapiens)
Organism: Homo sapiens
Gene: 39361_f_at
Selected probe(set): 209108_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 39361_f_at (209108_at) across 6674 perturbations tested by GENEVESTIGATOR:
colorectal cancer study 43 (metastase; brain) / colorectal cancer study 43 (metastase; lung)
Relative Expression (log2-ratio):-4.2706394Number of Samples:2 / 5
Experimental | colorectal cancer study 43 (metastase; brain) |
Metastatic tumor tissue obtained from the brain of patients with primary colorectal adenocarcinoma. | |
Control | colorectal cancer study 43 (metastase; lung) |
Metastatic tumor tissue obtained from the lung of patients with primary colon adenocarcinoma. |
colorectal cancer study 43 (metastase; brain) / colorectal cancer study 43 (metastase; liver)
Relative Expression (log2-ratio):-3.7073784Number of Samples:2 / 25
Experimental | colorectal cancer study 43 (metastase; brain) |
Metastatic tumor tissue obtained from the brain of patients with primary colorectal adenocarcinoma. | |
Control | colorectal cancer study 43 (metastase; liver) |
Metastatic tumor tissue obtained from the liver of patients with primary colon adenocarcinoma. |
brain tumor study 1 (ependymoma) / normal brain tissue
Relative Expression (log2-ratio):3.2022324Number of Samples:46 / 12
Experimental | brain tumor study 1 (ependymoma) |
Primary tumor tissue sample from the brain of patients with ependymoma. | |
Control | normal brain tissue |
Histologically normal and non-neoplastic tissue sample from different brain anatomical sites of patients with primary brain tumors. |
HIV-associated neurocognitive disorder study 3 (HIVE) / HIV-associated neurocognitive disorder study 2 (HIVE)
Relative Expression (log2-ratio):-3.2022066Number of Samples:2 / 2
Experimental | HIV-associated neurocognitive disorder study 3 (HIVE) |
Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from patients with HIV encephalitis (HIVE). HIVE was limited to the basal ganglia. The patients did not receive any antiretroviral therapy (ART). | |
Control | HIV-associated neurocognitive disorder study 2 (HIVE) |
Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from patients with HIV encephalitis (HIVE). The patients received an antiretroviral therapy (ART). |
myotonic dystrophy study 4 (deltoid muscle; DM-like) / normal skeletal muscle tisuue (fetal)
Relative Expression (log2-ratio):-3.066308Number of Samples:3 / 3
Experimental | myotonic dystrophy study 4 (deltoid muscle; DM-like) |
Deltoid muscle biopsies obtained from patients with myotonic-like dystrophy (DMx; DM-like; no DMPK or ZNF9 expansion). | |
Control | normal skeletal muscle tisuue (fetal) |
Commercially purchased normal fetal skeletal muscle tissue samples. |
myotonic dystrophy study 4 (biceps brachii; DM-like) / normal skeletal muscle tisuue (fetal)
Relative Expression (log2-ratio):-3.012351Number of Samples:9 / 3
Experimental | myotonic dystrophy study 4 (biceps brachii; DM-like) |
Biceps brachii biopsies obtained from patients with myotonic-like dystrophy (DMx; DM-like; no DMPK or ZNF9 expansion). | |
Control | normal skeletal muscle tisuue (fetal) |
Commercially purchased normal fetal skeletal muscle tissue samples. |
glioma study 16 (astrocytoma) / normal brain tissue
Relative Expression (log2-ratio):2.8764048Number of Samples:8 / 2
Experimental | glioma study 16 (astrocytoma) |
Primary astrocytoma tissues obtained from the operating room. Tumors were diagnosed and graded according to the current WHO classification (grade III-IV). | |
Control | normal brain tissue |
Normal brain tissue sample from healthy donors. |
myotonic dystrophy study 4 (skeletal muscle; DM2) / normal skeletal muscle tisuue (fetal)
Relative Expression (log2-ratio):-2.8096647Number of Samples:8 / 3
Experimental | myotonic dystrophy study 4 (skeletal muscle; DM2) |
Unspecified skeletal muscle biopsies obtained from patients with myotonic dystrophy type 2 (DM2). | |
Control | normal skeletal muscle tisuue (fetal) |
Commercially purchased normal fetal skeletal muscle tissue samples. |
myotonic dystrophy study 4 (biceps brachii; DM2) / normal skeletal muscle tisuue (fetal)
Relative Expression (log2-ratio):-2.7976675Number of Samples:3 / 3
Experimental | myotonic dystrophy study 4 (biceps brachii; DM2) |
Biceps brachii biopsies obtained from patients with myotonic dystrophy type 2 (DM2). | |
Control | normal skeletal muscle tisuue (fetal) |
Commercially purchased normal fetal skeletal muscle tissue samples. |
Langerhans cell histiocytosis study 2 (multifocal) / normal epidermal Langerhans cell sample
Relative Expression (log2-ratio):-2.6694274Number of Samples:2 / 10
Experimental | Langerhans cell histiocytosis study 2 (multifocal) |
Langerhans cell histiocytes (LCH, CD207+) samples isolated from LCH lesions of patients with multifocal (bone, skin lesions) disease. | |
Control | normal epidermal Langerhans cell sample |
Normal epidermal Langerhans cells (CD207+) were isolated from skin of children donors (age < 18 years). The Langerhans cells were isolated from presumably healthy tissue. |