Organism: Homo sapiens
Gene: 39385_at
Selected probe(set): 202888_s_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 39385_at (202888_s_at) across 6674 perturbations tested by GENEVESTIGATOR:

Relative Expression (log2-ratio):-7.149596
Number of Samples:24 / 3

Experimental	colorectal cancer study 4 (recurring)
	LCM-tumor tissue samples of patients who received resection after diagnosis of primary colorectal cancer. Patients developed metastatic recurrence during follow-up after surgery.
Control	adjacent colon tissue (recurring)
	Histologically normal colon tissue samples from patients with primary colorectal cancer collected after resection. Tissue was further extracted using laser-capture microdissection (LCM). With metastatic recurrence after resection during follow-up.

Relative Expression (log2-ratio):-6.9345264
Number of Samples:3 / 4

Experimental	colorectal adenoma study 1 (small)
	Ascending colon biopsies of colorectal adenomas (size: 1cm - 2cm).
Control	adjacent colon mucosa tissue
	Biopsies of ascending colon mucosa from adjacent tumor tissue.

Relative Expression (log2-ratio):-6.564627
Number of Samples:3 / 3

Experimental	HIF-1a/HIF-2a depletion study 1 (hypoxia; HK2)
	Proximal tubule epithelial cell line HK-2 with shRNA-mediated stable knock-down of HIF-1a and HIF-2a (Hypoxia-inducible factor 1-alpha and Hypoxia-inducible factor 2-alpha) 24 hours after treatment with hypoxia (20% O2). HK-2 cells were cultured in DMEM/F-12 supplemented with 10% fetal calf serum (FCS), 1% ITS, hydrocortisone, and antibiotics. The cells were incubated at 37 °C.
Control	HIF-1a/HIF-2a depletion study 1 (normoxia; AB81)
	Human podocyte cells AB81 with shRNA-mediated stable knock-down of HIF-1a and HIF-2a (Hypoxia-inducible factor 1-alpha and Hypoxia-inducible factor 2-alpha) 24 hours after treatment with normoxia (20% O2). Conditionally immortalized human podocytes AB81 were cultured under permissive conditions (33 °C) in RPMI-1640 supplemented with 10% FBS, antibiotics, and 1% ITS. Differentiation was induced by thermoshift to 37 °C in 6-well plates.

Relative Expression (log2-ratio):-6.0233994
Number of Samples:2 / 5

Experimental	connective/soft tissue cancer study 1 (PDX; connective and soft tissue, pleomorphic rhabdomyosarcoma, adult type; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary connective and soft tissue, pleomorphic rhabdomyosarcoma, adult type of the soft tissue (subcutaneously implanted).
Control	connective/soft tissue cancer study 1 (PDX; connective and soft tissue, fibromyxosarcoma; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary connective and soft tissue, fibromyxosarcoma of the soft tissue (subcutaneously implanted).

Relative Expression (log2-ratio):-5.914118
Number of Samples:4 / 3

Experimental	renal cell carcinoma study 6 (chromophobe type)
	Tumor tissue samples from the kidney of patients with chromophobe renal cell carcinoma (cRCC).
Control	normal kidney tissue (adult)
	Normal adult kidney tissue samples.

Relative Expression (log2-ratio):5.6573877
Number of Samples:3 / 3

Experimental	CD44s overexpr. study 1
	Human embryonic kidney cell line HEK-293 transfected with pcDNA3.1(-) vector containing codon-optimized human CD44 sequence for expression.
Control	normal HEK-293 cell sample
	Untransfected, native human embryonic kidney cell line HEK-293 cell samples.

Relative Expression (log2-ratio):-5.6262417
Number of Samples:2 / 5

Experimental	connective/soft tissue cancer study 1 (PDX; connective and soft tissue, leiomyosarcoma, NOS; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary connective and soft tissue, leiomyosarcoma, NOS of the soft tissue (subcutaneously implanted).
Control	connective/soft tissue cancer study 1 (PDX; connective and soft tissue, fibromyxosarcoma; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary connective and soft tissue, fibromyxosarcoma of the soft tissue (subcutaneously implanted).

Relative Expression (log2-ratio):-5.618395
Number of Samples:4 / 3

Experimental	oxyphilic adenoma study 1
	Tumor tissue samples from the kidney of patients with oxyphilic adenoma (renal oncocytoma).
Control	normal kidney tissue (adult)
	Normal adult kidney tissue samples.

Relative Expression (log2-ratio):-5.5309076
Number of Samples:6 / 6

Experimental	prostate cancer study 1 (meta.)
	Metastatic prostate cancer samples.
Control	benign prostate tissue
	Benign prostate samples.

Relative Expression (log2-ratio):-5.4912586
Number of Samples:6 / 6

Experimental	pancreatic cancer study 3 (ipma)
	Intraductal papillary mucinous adenoma from patients with pancreatic cancer.
Control	normal pancreas tissue
	Normal human pancreatic tissue.