TOP TEN perturbations for 39408_at (Homo sapiens)
Organism: Homo sapiens
Gene: 39408_at
Selected probe(set): 202366_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 39408_at (202366_at) across 6674 perturbations tested by GENEVESTIGATOR:
colorectal cancer study 4 (recurring) / adjacent colon tissue (recurring)
Relative Expression (log2-ratio):-2.259429Number of Samples:24 / 3
Experimental | colorectal cancer study 4 (recurring) |
LCM-tumor tissue samples of patients who received resection after diagnosis of primary colorectal cancer. Patients developed metastatic recurrence during follow-up after surgery. | |
Control | adjacent colon tissue (recurring) |
Histologically normal colon tissue samples from patients with primary colorectal cancer collected after resection. Tissue was further extracted using laser-capture microdissection (LCM). With metastatic recurrence after resection during follow-up. |
colorectal cancer study 4 (non-recurring) / adjacent colon tissue (non-recurring)
Relative Expression (log2-ratio):-2.1596308Number of Samples:76 / 18
Experimental | colorectal cancer study 4 (non-recurring) |
LCM-tumor tissue samples of patients who received resection after diagnosis of primary colorectal cancer. Patients did not develop metastatic recurrence during follow-up after surgery. | |
Control | adjacent colon tissue (non-recurring) |
Histologically normal colon tissue samples from patients with primary colorectal cancer collected after resection. Tissue was further extracted using laser-capture microdissection (LCM). No metastatic recurrence during follow-up. |
HCC study 23 (portal vein infiltration) / adjacent liver tissue
Relative Expression (log2-ratio):-2.1302423Number of Samples:3 / 10
Experimental | HCC study 23 (portal vein infiltration) |
Tumor liver tissue samples derived from patients with hepatocellular carcinoma (HCC) with portal vein infiltration. Samples were derived by laser capture microdissection (LCM) from patients with HCC from the Chinese National Human Genome Center at Shanghai. | |
Control | adjacent liver tissue |
Normal adjacent liver tissue samples derived from patients with hepatocellular carcinoma (HCC). Samples were derived by laser capture microdissection (LCM) from patients with HCC from the Chinese National Human Genome Center at Shanghai. |
colorectal cancer study 25 / adjacent colon tissue
Relative Expression (log2-ratio):-1.9998779Number of Samples:94 / 17
Experimental | colorectal cancer study 25 |
Human primary colorectal carcinoma sample. | |
Control | adjacent colon tissue |
Normal colon tissue samples adjacent to tumor from patients with colorectal cancer. |
colorectal cancer study 9 (metastatic progression) / adjacent colon tissue (metastatic progression)
Relative Expression (log2-ratio):-1.9453859Number of Samples:3 / 3
Experimental | colorectal cancer study 9 (metastatic progression) |
LCM-tumor tissue samples of patients who received resection after diagnosis of primary colorectal cancer with metastatic progression. | |
Control | adjacent colon tissue (metastatic progression) |
Histologically normal colon tissue samples from patients with primary colorectal cancer and metastatic progression collected after resection. Tissue was further extracted using laser-capture microdissection (LCM). |
brefeldin A study 1 (0.5ug/ml; HCT 116) / untreated HCT 116 cell sample
Relative Expression (log2-ratio):-1.8341455Number of Samples:3 / 3
Experimental | brefeldin A study 1 (0.5ug/ml; HCT 116) |
Human colon carcinoma cell line HCT116 was treated with 0.5 ug/ml brefeldin-A for 24 hours in McCOYs 5A medium supplemented with 10% heat inactivated FBS. ATC code:--- | |
Control | untreated HCT 116 cell sample |
Human colon carcinoma cell line HCT116 was grown in McCOYs 5A medium supplemented with 10% heat inactivated FBS. |
colorectal cancer study 4 (metastatic progression) / adjacent colon tissue (metastatic progression)
Relative Expression (log2-ratio):-1.8223877Number of Samples:23 / 4
Experimental | colorectal cancer study 4 (metastatic progression) |
LCM-tumor tissue samples of patients who received resection after diagnosis of primary colorectal cancer with metastatic progression. | |
Control | adjacent colon tissue (metastatic progression) |
Histologically normal colon tissue samples from patients with primary colorectal cancer and metastatic progression collected after resection. Tissue was further extracted using laser-capture microdissection (LCM). |
oxyphilic adenoma study 1 / normal kidney tissue (fetal)
Relative Expression (log2-ratio):1.7938385Number of Samples:4 / 2
Experimental | oxyphilic adenoma study 1 |
Tumor tissue samples from the kidney of patients with oxyphilic adenoma (renal oncocytoma). | |
Control | normal kidney tissue (fetal) |
Normal fetal kidney tissue samples. |
brefeldin A study 1 (0.5ug/ml; p53HCT116) / untreated p53HCT116 cell sample
Relative Expression (log2-ratio):-1.7325001Number of Samples:2 / 3
Experimental | brefeldin A study 1 (0.5ug/ml; p53HCT116) |
Derived human colon carcinoma cell line p53HCT116 with knockout gene for p53 was treated with 0.5 ug/ml brefeldin-A for 24 hours in McCOYs 5A medium supplemented with 10% heat inactivated FBS. ATC code:--- | |
Control | untreated p53HCT116 cell sample |
Derived human colon carcinoma cell line p53HCT116 with knockout gene for p53 was grown in McCOYs 5A medium supplemented with 10% heat inactivated FBS. |
colorectal cancer study 1 / normal colon tissue
Relative Expression (log2-ratio):-1.6671963Number of Samples:6 / 6
Experimental | colorectal cancer study 1 |
Laser microdissected human colorectal cancer sample. | |
Control | normal colon tissue |
Laser microdissected human colonic epithelial cells sample. |