Organism: Homo sapiens
Gene: 39411_at
Selected probe(set): 212665_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 39411_at (212665_at) across 6674 perturbations tested by GENEVESTIGATOR:

Relative Expression (log2-ratio):-4.805355
Number of Samples:3 / 3

Experimental	echinomycin study 1
	Echinomycin (100nM; 2h) treated human astroglioma (U251) cells, stimulated with deferoxamine (DFO; 300mM; 16h). ATC code:---
Control	deferoxamine study 5
	Untreated human astroglioma (U251) cells, stimulated with deferoxamine (DFO; 300mM; 16h). ATC code:

Relative Expression (log2-ratio):-4.1306715
Number of Samples:3 / 3

Experimental	actinomycin D study 1
	A549 human lung cancer cells were seeded eights days prior to treatment of non-cycling plateau phase cultures with drug. At four hours prior to RNA isolation, actinomycin D (5 ug/mL final concentration) was added to the culture. ATC code:
Control	mannitol treated A549 cell sample
	A549 human lung cancer cells were seeded eights days prior to treatment of non-cycling plateau phase cultures with drug. At four hours prior to RNA isolation, mannitol (5% final concentration) was added to the culture.

Relative Expression (log2-ratio):-3.6048622
Number of Samples:17 / 12

Relative Expression (log2-ratio):3.4403477
Number of Samples:3 / 3

Experimental	smoking study 14 (0.003puffs/ml)
	A549 lung cancer cells cultured in normal media and treated with 0.003 puffs/ml tobacco smoke condensate (TSC). TSC were derived from Kentucky Reference 1R4F research blend cigarettes at a concentration of 9 puffs, 10 mg tar/mL in DMSO.
Control	untreated A549 cell sample
	A549 lung cancer cells cultured in normal media, untreated.

Relative Expression (log2-ratio):-3.3132553
Number of Samples:4 / 4

Experimental	R547 study 1 (6h)
	Human prostate carcinoma metastatic cell line DU145 treated with the CDK inhibitor R547 [4-amino-2-(1-methanesulfonylpiperidin-4-ylamino) pyrimidin-5-yl]-(2, 3-difluoro-6-methoxyphenyl)methanone (Hoffmann-La Roche compound) for 6 hours at a 3xIC90 concentration of 5.1 μmol/L. ATC code:---
Control	vehicle (DMSO) treated DU145 cell sample
	Human prostate carcinoma metastatic cell line DU145 treated with vehicle (DMSO) for 6 hours.

Relative Expression (log2-ratio):-3.267393
Number of Samples:4 / 4

Experimental	B-CLL study 11 (rolipram)
	Peripheral blood mononuclear cells (PBMCs) obtained from chronic lymphocytic leukemia (CLL) patients and in vitro treated with rolipram (20 uM, cyclic nucleotide phosphodiesterase (PDE4) inhibitor) for 4 hours. PBMCs’ samples contained 90% CD19+ CD5+ B lineage CLL cells (B-CLL). Inclusion criteria: untreated CLL patients or at least 1 month after chemotherapy. Exclusion criteria: patients with active infections or other serious medical conditions or with white blood cell (WBC) counts of 15,000/l. ATC code:---
Control	rolipram study 4 (normal B-cell; 20uM)
	MACS purified resting B-cells from healthy donor peripheral blood treated with rolipram (20 uM, cyclic nucleotide phosphodiesterase (PDE4) inhibitor) for 4 hours. ATC code:---

Relative Expression (log2-ratio):-3.189291
Number of Samples:34 / 4

Experimental	adrenal gland cancer study 5 (ACC)
	Primary tumor tissue samples of the adrenal cortex from patients with adrenocortical carcinoma (ACC).
Control	normal adrenal cortex tissue
	Histological normal adrenal gland cortical tissue samples.

Relative Expression (log2-ratio):-3.1532898
Number of Samples:20 / 20

Experimental	IgA nephropathy study 8
	Hand-microdissected glomerular tissue samples derived from kidney biopsies of patients with IgA nephropathy (IgAN). Whole-core patient biopsies were obtained as part of routine renal biopsy procedures.
Control	control glomerulus tissue
	Hand-microdissected glomerular tissue samples derived from kidney biopsies of healthy living kidney transplant donors. The biopsies were taken after reperfusion in the kidney transplant recipient.

Relative Expression (log2-ratio):3.1237698
Number of Samples:3 / 3

Experimental	smoking study 14 (0.001puffs/ml)
	A549 lung cancer cells cultured in normal media and treated with 0.001 puffs/ml tobacco smoke condensate (TSC). TSC were derived from Kentucky Reference 1R4F research blend cigarettes at a concentration of 9 puffs, 10 mg tar/mL in DMSO.
Control	untreated A549 cell sample
	A549 lung cancer cells cultured in normal media, untreated.

Relative Expression (log2-ratio):-3.05054
Number of Samples:31 / 10

Experimental	adrenal gland cancer study 2
	Primary tumor tissue samples of the adrenal cortex from patients with adrenocortical carcinoma.
Control	normal adrenal cortex tissue
	Unaffected adrenal cortex tissue from control objects.