Organism: Homo sapiens
Gene: 39424_at
Selected probe(set): 209354_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 39424_at (209354_at) across 6674 perturbations tested by GENEVESTIGATOR:

Relative Expression (log2-ratio):-3.0033455
Number of Samples:3 / 3

Experimental	HIF-1a/HIF-2a depletion study 1 (hypoxia; HK2)
	Proximal tubule epithelial cell line HK-2 with shRNA-mediated stable knock-down of HIF-1a and HIF-2a (Hypoxia-inducible factor 1-alpha and Hypoxia-inducible factor 2-alpha) 24 hours after treatment with hypoxia (20% O2). HK-2 cells were cultured in DMEM/F-12 supplemented with 10% fetal calf serum (FCS), 1% ITS, hydrocortisone, and antibiotics. The cells were incubated at 37 °C.
Control	HIF-1a/HIF-2a depletion study 1 (normoxia; AB81)
	Human podocyte cells AB81 with shRNA-mediated stable knock-down of HIF-1a and HIF-2a (Hypoxia-inducible factor 1-alpha and Hypoxia-inducible factor 2-alpha) 24 hours after treatment with normoxia (20% O2). Conditionally immortalized human podocytes AB81 were cultured under permissive conditions (33 °C) in RPMI-1640 supplemented with 10% FBS, antibiotics, and 1% ITS. Differentiation was induced by thermoshift to 37 °C in 6-well plates.

Relative Expression (log2-ratio):-2.6462154
Number of Samples:2 / 2

Experimental	connective/soft tissue cancer study 1 (PDX; connective and soft tissue, leiomyosarcoma, NOS; metastatic)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from a metastasis of patients with primary connective and soft tissue, leiomyosarcoma, NOS of the soft tissue (subcutaneously implanted). Metastatic site of patient tumor sample is not reported.
Control	connective/soft tissue cancer study 1 (PDX; connective and soft tissue, clear cell sarcoma, NOS; metastatic)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from a metastasis of patients with primary connective and soft tissue, clear cell sarcoma, NOS of the soft tissue (subcutaneously implanted). Metastatic site of patient tumor sample is not reported.

Relative Expression (log2-ratio):-2.6275616
Number of Samples:3 / 3

Experimental	kidney transplantation study 16 (2 week)
	CD56+ natural killer cell samples derived from kidney transplant patients 2 weeks post-transplantation. Samples were collected 2 week after transplantation and administration of immunosuppressive therapy (day 1-4: methylprednisolone (60 mg); 3 doses: rabbit polyclonal anti-thymocyte globulin (ThymoglobulinH; 6 mg/kg); mycophenolate mofetil (CellCeptH); and tacrolimus (PrografH).
Control	normal natural killer cell (CD56+) sample
	CD56+ natural killer cell samples derived from healthy control subjects.

Relative Expression (log2-ratio):-2.5026464
Number of Samples:3 / 2

Experimental	connective/soft tissue cancer study 1 (PDX; connective and soft tissue, sarcoma, NOS; metastatic)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from a metastasis of patients with primary connective and soft tissue, sarcoma, NOS of the soft tissue (subcutaneously implanted). Metastatic site of patient tumor sample is not reported.
Control	connective/soft tissue cancer study 1 (PDX; connective and soft tissue, clear cell sarcoma, NOS; metastatic)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from a metastasis of patients with primary connective and soft tissue, clear cell sarcoma, NOS of the soft tissue (subcutaneously implanted). Metastatic site of patient tumor sample is not reported.

Relative Expression (log2-ratio):2.2003002
Number of Samples:8 / 6

Experimental	ovarian tumor study 11 (borderline)
	Human microdissected tumor cells from the ovary of patients with low-malignant (borderline) tumors of the ovary.
Control	normal ovarian surface epithelial cell sample
	Human microdissected ovarian surface epithelial cell sample from the ovary of healthy individuals.

Relative Expression (log2-ratio):-2.0574436
Number of Samples:8 / 12

Experimental	hepatocyte (ESC)
	Hepatocyte-like cells differentiated from embryonic stem cells (ESC)
Control	HepaRG
	Immortalized cancer cell line derived from female patient with hepatocellular carcinoma. Cells can be induced to differentiate into hepatocyte-like cells by exposure to DMSO. Synonyms:Hepa-RG Cellosaurus code:

Relative Expression (log2-ratio):1.9854031
Number of Samples:3 / 4

Experimental	melanoma study 1
	Skin tissue from melanoma patients.
Control	normal skin tissue
	Normal skin tissue.

Relative Expression (log2-ratio):1.8940544
Number of Samples:26 / 2

Experimental	renal cell carcinoma study 4
	Tumor tissue samples from the kidney of patients with renal cell carcinoma (RCC).
Control	normal kidney tissue (fetal)
	Normal fetal kidney tissue samples.

Relative Expression (log2-ratio):-1.8091478
Number of Samples:22 / 8

Experimental	ovarian tumor study 11 (high grade)
	Human microdissected tumor cells from the ovary of patients with high grade serous carcinoma.
Control	ovarian tumor study 11 (borderline)
	Human microdissected tumor cells from the ovary of patients with low-malignant (borderline) tumors of the ovary.

Relative Expression (log2-ratio):1.7568388
Number of Samples:11 / 6

Experimental	ovarian tumor study 11 (low grade)
	Human microdissected tumor cells from the ovary of patients with low grade serous carcinoma.
Control	normal ovarian surface epithelial cell sample
	Human microdissected ovarian surface epithelial cell sample from the ovary of healthy individuals.