TOP TEN perturbations for 39549_at (Homo sapiens)
Organism: Homo sapiens
Gene: 39549_at
Selected probe(set): 213462_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 39549_at (213462_at) across 6674 perturbations tested by GENEVESTIGATOR:
bone cancer study 1 (PDX; chondrosarcoma, NOS; primary) / bone cancer study 1 (PDX; myxoid chondrosarcoma; primary)
Relative Expression (log2-ratio):-3.4613743Number of Samples:2 / 2
Experimental | bone cancer study 1 (PDX; chondrosarcoma, NOS; primary) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary chondrosarcoma, NOS of the bone (subcutaneously implanted). | |
Control | bone cancer study 1 (PDX; myxoid chondrosarcoma; primary) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary myxoid chondrosarcoma of the bone (subcutaneously implanted). |
ovarian tumor study 30 (PDX; carcinoma, NOS; metastatic) / ovarian tumor study 30 (PDX; adenocarcinoma, NOS; primary)
Relative Expression (log2-ratio):-3.0727882Number of Samples:2 / 2
Experimental | ovarian tumor study 30 (PDX; carcinoma, NOS; metastatic) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from a metastasis of patients with primary carcinoma, NOS of the ovary (subcutaneously implanted). Metastatic site of patient tumor sample is not reported. | |
Control | ovarian tumor study 30 (PDX; adenocarcinoma, NOS; primary) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary adenocarcinoma, NOS of the ovary (subcutaneously implanted). |
bone cancer study 1 (PDX; osteosarcoma, NOS; primary) / bone cancer study 1 (PDX; myxoid chondrosarcoma; primary)
Relative Expression (log2-ratio):-3.0512047Number of Samples:2 / 2
Experimental | bone cancer study 1 (PDX; osteosarcoma, NOS; primary) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary osteosarcoma, NOS of the bone (subcutaneously implanted). | |
Control | bone cancer study 1 (PDX; myxoid chondrosarcoma; primary) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary myxoid chondrosarcoma of the bone (subcutaneously implanted). |
hepatocyte (ESC) / Hep-G2
Relative Expression (log2-ratio):-2.9984255Number of Samples:8 / 9
Experimental | hepatocyte (ESC) |
Hepatocyte-like cells differentiated from embryonic stem cells (ESC) | |
Control | Hep-G2 |
Human primary cancer cell line derived from the liver of a patient with hepatocellular carcinoma. Synonyms:HEP-G2; Hep G2; HEP G2; HepG2; HEPG2 Cellosaurus code: |
CH5183284 study 1 (MFE-280) / vehicle (DMSO) treated MFE-280 cell sample
Relative Expression (log2-ratio):-2.8168936Number of Samples:2 / 2
Experimental | CH5183284 study 1 (MFE-280) |
Human endometrial cell line MFE-280 treated with 1 uM of FGFR inhibitor CH5183284 for 24 hours. ATC code:--- | |
Control | vehicle (DMSO) treated MFE-280 cell sample |
Human endometrial cell line MFE-280 treated with 0.1% DMSO for 24 hours. |
SDF study 4 / untreated MDA Mb231 cell sample
Relative Expression (log2-ratio):-2.7289696Number of Samples:3 / 6
Experimental | SDF study 4 |
MDA Mb231 cells treated with 75nM stromal derived factor (SDF; Cxcl12) for 6h. | |
Control | untreated MDA Mb231 cell sample |
Untreated MDA Mb231 cells harvested after 6h. |
lung cancer study 1 (PDX; large cell carcinoma, NOS; primary) / lung cancer study 1 (PDX; adenosquamous carcinoma; primary)
Relative Expression (log2-ratio):-2.6817694Number of Samples:4 / 4
Experimental | lung cancer study 1 (PDX; large cell carcinoma, NOS; primary) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary large cell carcinoma, NOS of the lung (subcutaneously implanted). | |
Control | lung cancer study 1 (PDX; adenosquamous carcinoma; primary) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary adenosquamous carcinoma of the lung (subcutaneously implanted). |
HIV-associated neurocognitive disorder study 7 (normal) / HIV-associated neurocognitive disorder study 6 (normal)
Relative Expression (log2-ratio):2.673626Number of Samples:2 / 2
Experimental | HIV-associated neurocognitive disorder study 7 (normal) |
Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from patients with normal brain pathology. The patients received antiretroviral therapy (ART). | |
Control | HIV-associated neurocognitive disorder study 6 (normal) |
Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from patients with normal brain pathology. The patients did not receive any antiretroviral therapy (ART). |
ovarian tumor study 30 (PDX; serous cystadenocarcinoma, NOS; metastatic) / ovarian tumor study 30 (PDX; carcinoma, NOS; metastatic)
Relative Expression (log2-ratio):2.6577291Number of Samples:8 / 2
Experimental | ovarian tumor study 30 (PDX; serous cystadenocarcinoma, NOS; metastatic) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from a metastasis of patients with primary serous cystadenocarcinoma, NOS of the ovary (subcutaneously implanted). Metastatic site of patient tumor sample is not reported. | |
Control | ovarian tumor study 30 (PDX; carcinoma, NOS; metastatic) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from a metastasis of patients with primary carcinoma, NOS of the ovary (subcutaneously implanted). Metastatic site of patient tumor sample is not reported. |
medulloblastoma study 2 / non-tumor brain tissue
Relative Expression (log2-ratio):-2.6440668Number of Samples:4 / 9
Experimental | medulloblastoma study 2 |
Primary tumor tissue sample from the infratentorial brain of pediatric patients with large-cell anaplastic medulloblastoma. | |
Control | non-tumor brain tissue |
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor. |