Organism: Homo sapiens
Gene: 39556_at
Selected probe(set): 212071_s_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 39556_at (212071_s_at) across 6674 perturbations tested by GENEVESTIGATOR:

Relative Expression (log2-ratio):-4.4380865
Number of Samples:2 / 2

Experimental	zalypsis study 2
	OPM1 multiple myeloma cells treated in vitro with zalypsis (5 nM), a novel marine-derived compound with potent antimyeloma activity. Cells were harvested at the beginning of induction of cell death (15-20% cell death as assessed by Annexin V-FITC staining). ATC code:---
Control	untreated OPM1 cell sample
	OPM1 multiple myeloma cells untreated.

Relative Expression (log2-ratio):-3.9222155
Number of Samples:3 / 3

Experimental	oncolytic herpes simplex virus study 2
	Human malignant peripheral nerve sheath tumor (S462) cells infected with G207, an ICP34.5-deleted oncolytic herpes simplex virus (oHSV) for 6 hours.
Control	mock infected peripheral nerve sheath tumor (S462) cell sample
	Human malignant peripheral nerve sheath tumor (S462) cells mock infected for 6 hours.

Relative Expression (log2-ratio):-3.884554
Number of Samples:7 / 22

Experimental	sarcoidosis study 6 (orbital adipose tissue)
	Orbital adipose tissue samples obtained from patients who suffered from sarcoidosis. Biopsies were formalin-fixed and paraffin-embedded.
Control	normal orbital adipose tissue
	Normal orbital adipose tissue samples. Samples were obtained from subjects with no history of orbital disease at the time of surgery such as fat typically excised and discarded as part of routine blepharoplasty or retrobulbar fat that is snared with the eye during enucleation. Biopsies were formalin-fixed and paraffin-embedded.

Relative Expression (log2-ratio):-3.8059206
Number of Samples:3 / 3

Experimental	galectin-1 study 1
	Monocytes were plated in 12-well plates and differentiated in RPMI 1640 containing 10% FBS plus 50 ng/ml (>500 U/ml) GM-CSF and 100 ng/ml (>500 U/ml) IL-4 for 5 days. At day 5, galectin-1 (20 μM) in the presence of 10 μg/ml polymyxin B was added. At 18 h after treatment, total RNA was isolated.
Control	vehicle (DTT/polym. B) treated monocyte sample
	Monocytes were plated in 12-well plates and differentiated in RPMI 1640 containing 10% FBS plus 50 ng/ml (>500 U/ml) GM-CSF and 100 ng/ml (>500 U/ml) IL-4 for 5 days. At day 5, vehicle consisting of equivalent volume of 8 mM DTT (galectin-1 storage buffer) and 10 μg/ml polymyxin B was added. At 18 h after treatment, total RNA was isolated.

Relative Expression (log2-ratio):3.2728615
Number of Samples:27 / 7

Experimental	thyroid eye disease study 1 (orbital adipose tissue)
	Orbital adipose tissue samples obtained from patients who suffered from thyroid eye disease (TED). Biopsies were formalin-fixed and paraffin-embedded.
Control	sarcoidosis study 6 (orbital adipose tissue)
	Orbital adipose tissue samples obtained from patients who suffered from sarcoidosis. Biopsies were formalin-fixed and paraffin-embedded.

Relative Expression (log2-ratio):3.0797071
Number of Samples:3 / 6

Experimental	human AB serum study 1 (late)
	Monocytes, cultured in RPMI medium containing 10% human AB serum (HS) instead of FBS, and 500 U/ml IL-4 and 800 U/ml GM-CSF for 5 days. Cytokine treatment was repeated at day 3.
Control	IL-4; GM-CSF study 1 (late)
	Monocytes, cultured with vehicle (DMSO/ethanol) and 500 U/ml IL-4 and 800 U/ml GM-CSF for 5 days. Cytokine treatment was repeated at day 3.

Relative Expression (log2-ratio):-2.9761896
Number of Samples:3 / 3

Experimental	LPS study 2
	Cultured THP-1 mononuclear cells were treated with lipopolysaccharide (1 microgram/ml) for 4 hours at 37°C. ATC code:---
Control	untreated THP-1 cell sample
	Cultured THP-1 mononuclear cells were cultured in basal growth media at 37°C.

Relative Expression (log2-ratio):-2.9635773
Number of Samples:9 / 22

Experimental	granulomatosis with polyangiitis study 3 (orbital adipose tissue)
	Orbital adipose tissue samples obtained from patients who suffered from granulomatosis with polyangiitis (GPA). Biopsies were formalin-fixed and paraffin-embedded.
Control	normal orbital adipose tissue
	Normal orbital adipose tissue samples. Samples were obtained from subjects with no history of orbital disease at the time of surgery such as fat typically excised and discarded as part of routine blepharoplasty or retrobulbar fat that is snared with the eye during enucleation. Biopsies were formalin-fixed and paraffin-embedded.

Relative Expression (log2-ratio):2.9344673
Number of Samples:10 / 11

Experimental	IgG; C3bi stimulation study 1 (late)
	Polymorphonuclear leukocytes (PMNs) from healthy donors, incubated with IgG- and C3bi-coated latex beads at 37°C in a CO2 incubator for 6h. ATC code:---
Control	normal polymorphnuclear leukocyte sample
	Polymorphonuclear leukocytes (PMNs) from healthy donors, incubated without IgG- and C3bi-coated latex beads at 37°C in a CO2 incubator for 6h.

Relative Expression (log2-ratio):-2.9177065
Number of Samples:3 / 6

Experimental	SDF study 4
	MDA Mb231 cells treated with 75nM stromal derived factor (SDF; Cxcl12) for 6h.
Control	untreated MDA Mb231 cell sample
	Untreated MDA Mb231 cells harvested after 6h.