Organism: Homo sapiens
Gene: 39569_at
Selected probe(set): 204503_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 39569_at (204503_at) across 6674 perturbations tested by GENEVESTIGATOR:

Relative Expression (log2-ratio):-2.9441023
Number of Samples:40 / 2

Experimental	melanoma study 34 (metastatic)
	Metastatic tumor tissue sample obtained from the patients with metastatic malignant melanoma of the skin. Metastatic samples composed of 22 macroscopic lymph node metastases, 16 subcutaneous metastases and 2 solid organ metastases (adrenal and brain).
Control	melanoma study 34 (in situ)
	Tumor tissue from the skin of patients with melanoma in situ.

Relative Expression (log2-ratio):-2.8666277
Number of Samples:20 / 18

Experimental	esophageal adenocarcinoma study 1
	Esophageal adenocarcinoma (EAC) samples of affected epithelium recovered by laser capture microdissection technique.
Control	normal esophageal epithelium sample
	Histologically normal esophageal squamous cell epithelium biopsy samples from patients that were investigated for esophageal pain, but diagnosed as healthy.

Relative Expression (log2-ratio):-2.8353128
Number of Samples:11 / 64

Experimental	Merkel cell carcinoma study 3 (metastatic)
	Metastatic tumor tissue from different metastatic sites (skin, lymph node, parotid gland) of patients with Merkel cell carcinoma of the skin.
Control	normal skin tissue
	Normal skin samples from healthy donors.

Relative Expression (log2-ratio):-2.7935686
Number of Samples:40 / 4

Experimental	melanoma study 34 (metastatic)
	Metastatic tumor tissue sample obtained from the patients with metastatic malignant melanoma of the skin. Metastatic samples composed of 22 macroscopic lymph node metastases, 16 subcutaneous metastases and 2 solid organ metastases (adrenal and brain).
Control	normal skin tissue
	Normal skin tissue.

Relative Expression (log2-ratio):-2.7658577
Number of Samples:19 / 4

Experimental	Merkel cell carcinoma study 3 (primary)
	Primary tumor tissue from the skin of patients with Merkel cell carcinoma.
Control	skin squamous cell carcinoma study 6
	Primary tumor tissue from the skin of patients with squamous cell carcinoma (SCC).

Relative Expression (log2-ratio):-2.6811619
Number of Samples:17 / 18

Experimental	Barrett's esophagus study 3
	Esophageal epithelium samples from areas with Barrett's esophagus metaplasia which were recovered by laser capture microdissection.
Control	normal esophageal epithelium sample
	Histologically normal esophageal squamous cell epithelium biopsy samples from patients that were investigated for esophageal pain, but diagnosed as healthy.

Relative Expression (log2-ratio):-2.6243134
Number of Samples:19 / 64

Experimental	Merkel cell carcinoma study 3 (primary)
	Primary tumor tissue from the skin of patients with Merkel cell carcinoma.
Control	normal skin tissue
	Normal skin samples from healthy donors.

Relative Expression (log2-ratio):-2.2185316
Number of Samples:8 / 18

Experimental	esophageal squamous cell carcinoma study 1
	Esophageal squamous cell carcinoma (ESCC) biopsy samples from chemotherapy-naive patients with histological grading G1 (well differentiated) and UICC stage II and III, which undergone esophagectomy.
Control	normal esophageal epithelium sample
	Histologically normal esophageal squamous cell epithelium biopsy samples from patients that were investigated for esophageal pain, but diagnosed as healthy.

Relative Expression (log2-ratio):-2.2184744
Number of Samples:3 / 3

Experimental	wound healing study 2 (ex vivo; DMSO)
	Ex vivo skin samples obtained from healthy donors following reduction surgery of abdomen, and incubated in culture medium containing DMSO for 4 days. To make sure that mainly epidermis was present in the samples, as much dermal tissue as possible was removed by dissection. Skin was sliced into 1x10 mm slices and incubated in keratinocyte medium for four days with 1:1000 fold dilution of DMSO. The cultivation was performed in serum-free keratinocyte medium supplemented with transferrin, hEGF (0.15 ng/mL), 0.5 mg/mL hydrocortisone, gentamicin, amphotericin B, and epinephrine but without insulin.
Control	normal skin tissue (ex vivo)
	Normal skin samples obtained from healthy donors following reduction surgery of abdomen. To make sure that mainly epidermis was present in the samples, as much dermal tissue as possible was removed by dissection.

Relative Expression (log2-ratio):-2.1800146
Number of Samples:14 / 2

Experimental	melanoma study 34 (primary)
	Primary tumor tissue from the skin of patients with primary cutaneous melanoma (PCM). PCM consisted of 2 thin melanomas (< 1 mm; T1), 3 intermediate-thickness melanomas (1–4 mm; T2-3), and 9 thick melanomas (> 4 mm; T4).
Control	melanoma study 34 (in situ)
	Tumor tissue from the skin of patients with melanoma in situ.