TOP TEN perturbations for 39577_at (Homo sapiens)
Organism: Homo sapiens
Gene: 39577_at
Selected probe(set): 213456_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 39577_at (213456_at) across 6674 perturbations tested by GENEVESTIGATOR:
L3.6pl / COLO 357/FG
Relative Expression (log2-ratio):6.6532383Number of Samples:3 / 3
Experimental | L3.6pl |
Human, xenograft derived, pancreatic carcinoma cell line with high metastatic potential. The cell line is derived from liver metastases formed in mouse xenograft model. The mouse was originally injected with L3.3 pancreatic carcinoma cell line. Parental cell line:: COLO 357 Synonyms:L3.6PL; L3_6PL; L3.6 pancreas-liver; Colo357L3.6pl Cellosaurus code: | |
Control | COLO 357/FG |
Human, xenograft derived, pancreatic carcinoma cell line with low metastatic potential. The cell line is derived from unknown metastatic site of mouse xenograft model. The mouse was originally injected with COLO357 human pancreatic adenocarcinoma cell line. Parental cell line:: COLO 357 Synonyms:FG; Colo 357 FG; COLO 357 Fast Growing; Colo 357/FG; Colo357FG; COLO357FG; FG/COLO357 Cellosaurus code: |
MALT lymphoma study 1 / normal spleen tissue
Relative Expression (log2-ratio):5.9343286Number of Samples:8 / 6
Experimental | MALT lymphoma study 1 |
Human t(11;18)-negative mucosa-associated lymphoid tissue (MALT) lymphoma cells. | |
Control | normal spleen tissue |
Normal human spleen tissue sample. |
basal cell carcinoma study 3 / normal epidermal keratinocytes
Relative Expression (log2-ratio):5.466546Number of Samples:4 / 2
Experimental | basal cell carcinoma study 3 |
Primary tumor tissue from the eyelid of patients with basal cell carcinoma (BCC). | |
Control | normal epidermal keratinocytes |
Normal human epidermal keratinocytes (NHEK) (Kurabo Ind., Ltd., Osaka, Japan) cultured in HuMedia-KB2 medium at 37°C in humidified air containing 5% CO2. |
Merkel cell carcinoma study 3 (primary) / basal cell carcinoma study 2
Relative Expression (log2-ratio):-5.3409243Number of Samples:19 / 2
Experimental | Merkel cell carcinoma study 3 (primary) |
Primary tumor tissue from the skin of patients with Merkel cell carcinoma. | |
Control | basal cell carcinoma study 2 |
Primary tumor tissue from the skin of patients with basal cell carcinoma (BCC). |
basal cell carcinoma study 6 (primary) / melanoma study 34 (primary)
Relative Expression (log2-ratio):4.9610357Number of Samples:15 / 14
Experimental | basal cell carcinoma study 6 (primary) |
Primary tumor tissue from the skin of patients with primary basal cell carcinoma (BCC). | |
Control | melanoma study 34 (primary) |
Primary tumor tissue from the skin of patients with primary cutaneous melanoma (PCM). PCM consisted of 2 thin melanomas (< 1 mm; T1), 3 intermediate-thickness melanomas (1–4 mm; T2-3), and 9 thick melanomas (> 4 mm; T4). |
lung adenocarcinoma study 6 (K-RAS mut) / adjacent lung tissue
Relative Expression (log2-ratio):-4.8663206Number of Samples:6 / 20
Experimental | lung adenocarcinoma study 6 (K-RAS mut) |
Primary tumor sample from patients with stage II adenocarcinoma carrying a K-RAS mutation. | |
Control | adjacent lung tissue |
Adjacent and histologically normal, non-tumorous lung tissue samples from patients with lung adenocarcinoma. |
lung adenocarcinoma study 3 (negative) / normal lung tissue
Relative Expression (log2-ratio):-4.764474Number of Samples:9 / 3
Experimental | lung adenocarcinoma study 3 (negative) |
Primary lung adenocarcinoma samples, with bone marrow negative for early disseminated tumor cells (DTCs). The presence of DTCs can predict the subsequent occurrence of overt metastasis and survival in lung cancer. | |
Control | normal lung tissue |
Normal lung tissue. |
expO kidney cancer study 1 (renal cell carcinoma, sarcomatoid; primary) / expO kidney cancer study 1 (papillary adenocarcinoma, NOS; primary)
Relative Expression (log2-ratio):-4.583391Number of Samples:3 / 22
Experimental | expO kidney cancer study 1 (renal cell carcinoma, sarcomatoid; primary) |
Primary tumor tissue samples obtained from the kidney of patients with renal cell carcinoma, sarcomatoid. | |
Control | expO kidney cancer study 1 (papillary adenocarcinoma, NOS; primary) |
Primary tumor tissue samples obtained from the kidney of patients with papillary adenocarcinoma (NOS). |
renal cell carcinoma study 1 (prim. tumor) / adjacent kidney tissue
Relative Expression (log2-ratio):-4.5485888Number of Samples:3 / 3
Experimental | renal cell carcinoma study 1 (prim. tumor) |
Tumor tissue from the primary tumor of patients with renal cell carcinoma (RCC). | |
Control | adjacent kidney tissue |
Histologically normal tissue from an unaffected site (renal tubules) of patients with renal cell carcinoma (RCC) of the clear cell type. |
renal cell carcinoma study 1 (metastasis) / adjacent kidney tissue
Relative Expression (log2-ratio):-4.517379Number of Samples:3 / 3
Experimental | renal cell carcinoma study 1 (metastasis) |
Tumor tissue from metastases of patients with renal cell carcinoma (RCC). | |
Control | adjacent kidney tissue |
Histologically normal tissue from an unaffected site (renal tubules) of patients with renal cell carcinoma (RCC) of the clear cell type. |