TOP TEN perturbations for 39583_at (Homo sapiens)
Organism: Homo sapiens
Gene: 39583_at
Selected probe(set): 205154_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 39583_at (205154_at) across 6674 perturbations tested by GENEVESTIGATOR:
breast cancer study 42 (metastase; lymph node) / breast cancer study 42 (metastase; chest wall)
Relative Expression (log2-ratio):-2.514988Number of Samples:7 / 2
Experimental | breast cancer study 42 (metastase; lymph node) |
Metastatic tumor tissue obtained from the lymph node of patients with primary breast adenocarcinoma. | |
Control | breast cancer study 42 (metastase; chest wall) |
Metastatic tumor tissue obtained from the chest wall of patients with primary breast adenocarcinoma. |
breast cancer study 42 (metastase; liver) / breast cancer study 42 (metastase; chest wall)
Relative Expression (log2-ratio):-2.2636604Number of Samples:3 / 2
Experimental | breast cancer study 42 (metastase; liver) |
Metastatic tumor tissue obtained from the liver of patients with primary breast adenocarcinoma. | |
Control | breast cancer study 42 (metastase; chest wall) |
Metastatic tumor tissue obtained from the chest wall of patients with primary breast adenocarcinoma. |
stem cell differentiation study 41 (T3pi) / undifferentiated hES-T3 cell sample
Relative Expression (log2-ratio):1.9067049Number of Samples:2 / 3
Experimental | stem cell differentiation study 41 (T3pi) |
Sample of pancreatic islet-like cell clusters differentiated from human embryonic stem cells T3 with female karyotype. | |
Control | undifferentiated hES-T3 cell sample |
Undifferentiated human embryonic stem cells T3. |
brain tumor study 1 (medulloblastoma) / brain tumor study 1 (ependymoma)
Relative Expression (log2-ratio):-1.8127832Number of Samples:22 / 46
Experimental | brain tumor study 1 (medulloblastoma) |
Primary tumor tissue sample from the brain of patients with medulloblastoma. | |
Control | brain tumor study 1 (ependymoma) |
Primary tumor tissue sample from the brain of patients with ependymoma. |
male infertility study 1 (juvenile; Ad-) / normal testicular lobules tissue (mJS10)
Relative Expression (log2-ratio):1.8087568Number of Samples:2 / 8
Experimental | male infertility study 1 (juvenile; Ad-) |
Human testicular lobules biopsy samples isolated from prepubescent patients with undescended testes. Testes of these children contained very low level of A-dark (Ad-) spermatogonial cells. | |
Control | normal testicular lobules tissue (mJS10) |
Biopsies of human testicular lobules isolated from fertile vasectomized adult men with normal spermatogenesis. Histological analysis classified samples as mJS10 (modified Johnsen score 10). |
male infertility study 1 (juvenile; Ad+) / normal testicular lobules tissue (mJS10)
Relative Expression (log2-ratio):1.6128435Number of Samples:5 / 8
Experimental | male infertility study 1 (juvenile; Ad+) |
Human testicular lobules biopsy samples isolated from prepubescent patients with undescended testes. Testes of these children contained typical level of A-dark (Ad+) spermatogonial cells. | |
Control | normal testicular lobules tissue (mJS10) |
Biopsies of human testicular lobules isolated from fertile vasectomized adult men with normal spermatogenesis. Histological analysis classified samples as mJS10 (modified Johnsen score 10). |
stem cell differentiation study 41 (T3pi) / stem cell differentiation study 41 (hES-T3 EB)
Relative Expression (log2-ratio):1.5917587Number of Samples:2 / 2
Experimental | stem cell differentiation study 41 (T3pi) |
Sample of pancreatic islet-like cell clusters differentiated from human embryonic stem cells T3 with female karyotype. | |
Control | stem cell differentiation study 41 (hES-T3 EB) |
Sample of embryonic bodies (EB) differentiated from human embryonic stem cells T3 with female karyotype. |
TGF-ß study 5 (intermediate) / untreated A549 cell sample
Relative Expression (log2-ratio):1.4988842Number of Samples:9 / 3
Experimental | TGF-ß study 5 (intermediate) |
Human A549 cells were treated with 5ng/ml porcine TGF-ß after serum-starving for 24h. Samples were taken 8, 16, 24 hours after TGF-ß treatment. | |
Control | untreated A549 cell sample |
A549 cells were grown for 24 hours. Samples were taken immediately before TGF-ß treatment. |
brain tumor study 1 (glioblastoma) / brain tumor study 1 (ependymoma)
Relative Expression (log2-ratio):-1.4335661Number of Samples:34 / 46
Experimental | brain tumor study 1 (glioblastoma) |
Primary tumor tissue sample from the brain of patients with glioblastoma multiformae. | |
Control | brain tumor study 1 (ependymoma) |
Primary tumor tissue sample from the brain of patients with ependymoma. |
ovarian tumor study 16 / normal ovarian surface epithelial cell sample
Relative Expression (log2-ratio):1.4252033Number of Samples:3 / 5
Experimental | ovarian tumor study 16 |
Human epithelial tumor cell samples from the ovary of patients with papillary serous carcinoma. Samples were derived by laser capture microdissection (LCM). | |
Control | normal ovarian surface epithelial cell sample |
Human epithelial cell samples from histopathological normal and non-cancerous ovary tissue. |