Organism: Homo sapiens
Gene: 39609_at
Selected probe(set): 206558_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 39609_at (206558_at) across 6674 perturbations tested by GENEVESTIGATOR:

Relative Expression (log2-ratio):-6.373951
Number of Samples:3 / 3

Experimental	HIF-1a/HIF-2a depletion study 1 (hypoxia; HK2)
	Proximal tubule epithelial cell line HK-2 with shRNA-mediated stable knock-down of HIF-1a and HIF-2a (Hypoxia-inducible factor 1-alpha and Hypoxia-inducible factor 2-alpha) 24 hours after treatment with hypoxia (20% O2). HK-2 cells were cultured in DMEM/F-12 supplemented with 10% fetal calf serum (FCS), 1% ITS, hydrocortisone, and antibiotics. The cells were incubated at 37 °C.
Control	HIF-1a/HIF-2a depletion study 1 (normoxia; AB81)
	Human podocyte cells AB81 with shRNA-mediated stable knock-down of HIF-1a and HIF-2a (Hypoxia-inducible factor 1-alpha and Hypoxia-inducible factor 2-alpha) 24 hours after treatment with normoxia (20% O2). Conditionally immortalized human podocytes AB81 were cultured under permissive conditions (33 °C) in RPMI-1640 supplemented with 10% FBS, antibiotics, and 1% ITS. Differentiation was induced by thermoshift to 37 °C in 6-well plates.

Relative Expression (log2-ratio):-3.6477318
Number of Samples:6 / 6

Experimental	TC-71
	Human primary cancer cell line derived from the humerus of a patient with Ewing sarcoma. Synonyms:TC71; GM11654 Cellosaurus code:
Control	TC-32
	Human primary cancer cell line derived from the unspecified origin of a patient with Ewing’s sarcoma. Synonyms:TC32 Cellosaurus code:

Relative Expression (log2-ratio):3.5966768
Number of Samples:7 / 6

Experimental	prostate cancer study 1 (prim.)
	Primary prostate cancer samples.
Control	benign prostate tissue
	Benign prostate samples.

Relative Expression (log2-ratio):-3.4594927
Number of Samples:26 / 3

Experimental	renal cell carcinoma study 4
	Tumor tissue samples from the kidney of patients with renal cell carcinoma (RCC).
Control	normal kidney tissue (adult)
	Normal adult kidney tissue samples.

Relative Expression (log2-ratio):-3.45498
Number of Samples:2 / 2

Experimental	bone cancer study 1 (PDX; chondroblastic osteosarcoma; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary chondroblastic osteosarcoma of the bone (subcutaneously implanted).
Control	bone cancer study 1 (PDX; myxoid chondrosarcoma; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary myxoid chondrosarcoma of the bone (subcutaneously implanted).

Relative Expression (log2-ratio):-3.3176012
Number of Samples:13 / 2

Experimental	ovarian tumor study 30 (PDX; serous cystadenocarcinoma, NOS; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary serous cystadenocarcinoma, NOS of the ovary (subcutaneously implanted).
Control	ovarian tumor study 30 (PDX; clear cell adenocarcinoma, NOS; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary clear cell adenocarcinoma, NOS of the ovary (subcutaneously implanted).

Relative Expression (log2-ratio):-3.2453327
Number of Samples:19 / 3

Experimental	renal cell carcinoma study 5 (papillary type)
	Tumor tissue samples from the kidney of patients with papillary renal cell carcinoma (pRCC).
Control	normal kidney tissue (adult)
	Normal adult kidney tissue samples.

Relative Expression (log2-ratio):-3.2274895
Number of Samples:4 / 3

Experimental	oxyphilic adenoma study 1
	Tumor tissue samples from the kidney of patients with oxyphilic adenoma (renal oncocytoma).
Control	normal kidney tissue (adult)
	Normal adult kidney tissue samples.

Relative Expression (log2-ratio):-3.1390762
Number of Samples:3 / 3

Experimental	renal cell carcinoma study 1 (prim. tumor)
	Tumor tissue from the primary tumor of patients with renal cell carcinoma (RCC).
Control	adjacent kidney tissue
	Histologically normal tissue from an unaffected site (renal tubules) of patients with renal cell carcinoma (RCC) of the clear cell type.

Relative Expression (log2-ratio):-3.0852308
Number of Samples:14 / 69

Experimental	clear cell renal cell carcinoma study 4 (stage 3)
	Primary tumor tissue from patients with stage 3 clear cell renal cell carcinoma (ccRCC).
Control	normal kidney tissue
	Normal kidney tissue samples obtained from healthy individuals.