TOP TEN perturbations for 39625_at (Homo sapiens)
Organism: Homo sapiens
Gene: 39625_at
Selected probe(set): 213929_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 39625_at (213929_at) across 6674 perturbations tested by GENEVESTIGATOR:
melanoma study 34 (metastatic) / melanoma study 34 (in situ)
Relative Expression (log2-ratio):-5.79782Number of Samples:40 / 2
Experimental | melanoma study 34 (metastatic) |
Metastatic tumor tissue sample obtained from the patients with metastatic malignant melanoma of the skin. Metastatic samples composed of 22 macroscopic lymph node metastases, 16 subcutaneous metastases and 2 solid organ metastases (adrenal and brain). | |
Control | melanoma study 34 (in situ) |
Tumor tissue from the skin of patients with melanoma in situ. |
melanoma study 34 (metastatic) / normal skin tissue
Relative Expression (log2-ratio):-5.688775Number of Samples:40 / 4
Experimental | melanoma study 34 (metastatic) |
Metastatic tumor tissue sample obtained from the patients with metastatic malignant melanoma of the skin. Metastatic samples composed of 22 macroscopic lymph node metastases, 16 subcutaneous metastases and 2 solid organ metastases (adrenal and brain). | |
Control | normal skin tissue |
Normal skin tissue. |
HCC827 / A-549
Relative Expression (log2-ratio):4.864407Number of Samples:6 / 6
Experimental | HCC827 |
Human primary cancer cell line derived from the lung of a patient with non-small-cell lung cancer. Synonyms:HCC-827; HCC0827 Cellosaurus code: | |
Control | A-549 |
Human primary cancer cell line derived from the lung of a patient with carcinoma. Synonyms:A 549; A549; NCI-A549; A549/ATCC; hA549 Cellosaurus code: |
melanoma study 34 (primary) / melanoma study 34 (in situ)
Relative Expression (log2-ratio):-4.6078587Number of Samples:14 / 2
Experimental | melanoma study 34 (primary) |
Primary tumor tissue from the skin of patients with primary cutaneous melanoma (PCM). PCM consisted of 2 thin melanomas (< 1 mm; T1), 3 intermediate-thickness melanomas (1–4 mm; T2-3), and 9 thick melanomas (> 4 mm; T4). | |
Control | melanoma study 34 (in situ) |
Tumor tissue from the skin of patients with melanoma in situ. |
melanoma study 34 (primary) / normal skin tissue
Relative Expression (log2-ratio):-4.4988136Number of Samples:14 / 4
Experimental | melanoma study 34 (primary) |
Primary tumor tissue from the skin of patients with primary cutaneous melanoma (PCM). PCM consisted of 2 thin melanomas (< 1 mm; T1), 3 intermediate-thickness melanomas (1–4 mm; T2-3), and 9 thick melanomas (> 4 mm; T4). | |
Control | normal skin tissue |
Normal skin tissue. |
basal cell carcinoma study 2 / normal skin tissue
Relative Expression (log2-ratio):-4.2799892Number of Samples:2 / 64
Experimental | basal cell carcinoma study 2 |
Primary tumor tissue from the skin of patients with basal cell carcinoma (BCC). | |
Control | normal skin tissue |
Normal skin samples from healthy donors. |
lung cancer study 1 (PDX; large cell carcinoma, NOS; primary) / lung cancer study 1 (PDX; adenosquamous carcinoma; primary)
Relative Expression (log2-ratio):-4.2456675Number of Samples:4 / 4
Experimental | lung cancer study 1 (PDX; large cell carcinoma, NOS; primary) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary large cell carcinoma, NOS of the lung (subcutaneously implanted). | |
Control | lung cancer study 1 (PDX; adenosquamous carcinoma; primary) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary adenosquamous carcinoma of the lung (subcutaneously implanted). |
HCC study 9 (HBV; HCV) / normal liver tissue
Relative Expression (log2-ratio):-4.1824636Number of Samples:2 / 10
Experimental | HCC study 9 (HBV; HCV) |
Liver tissue biopsy sample from patients with Hepatitis B and C infection related hepatocellular carcinoma (HCC) after resection. | |
Control | normal liver tissue |
Normal, non-tumor liver tissue. |
Langerhans cell histiocytosis study 2 (multisystem) / normal epidermal Langerhans cell sample
Relative Expression (log2-ratio):-4.148057Number of Samples:2 / 10
Experimental | Langerhans cell histiocytosis study 2 (multisystem) |
Langerhans cell histiocytes (LCH, CD207+) samples isolated from LCH lesions of patients with multifocal, multisystem (disseminated) disease. Both patients received chemotherapy. Sites of LCH lesions: subj.ID:1 (skin, lungs, multiple skull, mastoid, gingiva), subj.ID:13 (mandible, skull, vertebrae, recurrent orbit, liver, spleen, pituitary gland). | |
Control | normal epidermal Langerhans cell sample |
Normal epidermal Langerhans cells (CD207+) were isolated from skin of children donors (age < 18 years). The Langerhans cells were isolated from presumably healthy tissue. |
skin transplantation study 1 (3d) / normal skin tissue (skin grafting)
Relative Expression (log2-ratio):-4.0804644Number of Samples:6 / 8
Experimental | skin transplantation study 1 (3d) |
Human skin punch biopsy from patients after skin grafting. Sample was taken at the site of re-epithelialization 3 days after surgery. | |
Control | normal skin tissue (skin grafting) |
Skin biopsy samples from healthy control subjects after breast or abdomen reduction surgery. |