TOP TEN perturbations for 39651_at (Homo sapiens)
Organism: Homo sapiens
Gene: 39651_at
Selected probe(set): 1553015_a_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 39651_at (1553015_a_at) across 6674 perturbations tested by GENEVESTIGATOR:
glioma study 16 (LN-229) / normal astrocyte sample
Relative Expression (log2-ratio):2.042266Number of Samples:2 / 3
Experimental | glioma study 16 (LN-229) |
Human glioma cell line LN229 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37°C and 5% CO2. | |
Control | normal astrocyte sample |
Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations. |
glioma study 16 (LN-18) / normal astrocyte sample
Relative Expression (log2-ratio):2.0098352Number of Samples:2 / 3
Experimental | glioma study 16 (LN-18) |
Human glioma cell line LN018 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37C and 5% CO2. | |
Control | normal astrocyte sample |
Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations. |
lung adenocarcinoma study 9 (metastase; lymph node) / lung adenocarcinoma study 9 (metastase; brain)
Relative Expression (log2-ratio):-1.9377832Number of Samples:3 / 6
Experimental | lung adenocarcinoma study 9 (metastase; lymph node) |
Metastatic tumor tissue obtained from the lymph node of patients with primary lung adenocarcinoma. | |
Control | lung adenocarcinoma study 9 (metastase; brain) |
Metastatic tumor tissue obtained from the brain of patients with primary lung adenocarcinoma. |
breast cancer study 8 (primary) / normal breast tissue
Relative Expression (log2-ratio):1.9365463Number of Samples:13 / 4
Experimental | breast cancer study 8 (primary) |
Human primary infiltrating ductal carcinoma sample of a female patient with breast cancer. | |
Control | normal breast tissue |
Normal human breast samples of healthy female individuals. |
Merkel cell carcinoma study 3 (metastatic) / normal skin tissue
Relative Expression (log2-ratio):1.9060459Number of Samples:11 / 64
Experimental | Merkel cell carcinoma study 3 (metastatic) |
Metastatic tumor tissue from different metastatic sites (skin, lymph node, parotid gland) of patients with Merkel cell carcinoma of the skin. | |
Control | normal skin tissue |
Normal skin samples from healthy donors. |
glioma study 16 (LN-215) / normal astrocyte sample
Relative Expression (log2-ratio):1.8679171Number of Samples:2 / 3
Experimental | glioma study 16 (LN-215) |
Human glioma cell line LN215 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37°C and 5% CO2. | |
Control | normal astrocyte sample |
Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations. |
tunicamycin study 2 (2ug/ml; p53HCT116) / untreated p53HCT116 cell sample
Relative Expression (log2-ratio):-1.8568687Number of Samples:3 / 3
Experimental | tunicamycin study 2 (2ug/ml; p53HCT116) |
Derived human colon carcinoma cell line p53HCT116 with knockout gene for p53 was treated with 2 ug/ml tunicamycin for 24 hours in McCOYs 5A medium supplemented with 10% heat inactivated FBS. ATC code:--- | |
Control | untreated p53HCT116 cell sample |
Derived human colon carcinoma cell line p53HCT116 with knockout gene for p53 was grown in McCOYs 5A medium supplemented with 10% heat inactivated FBS. |
Merkel cell carcinoma study 3 (primary) / normal skin tissue
Relative Expression (log2-ratio):1.7538013Number of Samples:19 / 64
Experimental | Merkel cell carcinoma study 3 (primary) |
Primary tumor tissue from the skin of patients with Merkel cell carcinoma. | |
Control | normal skin tissue |
Normal skin samples from healthy donors. |
CH5183284 study 1 (HSC-39) / vehicle (DMSO) treated HSC-39 cell sample
Relative Expression (log2-ratio):-1.722271Number of Samples:2 / 2
Experimental | CH5183284 study 1 (HSC-39) |
Human gastric cell line HSC-39 treated with 1 uM of FGFR inhibitor CH5183284 for 24 hours. ATC code:--- | |
Control | vehicle (DMSO) treated HSC-39 cell sample |
Human gastric cell line HSC-39 treated with 0.1% DMSO for 24 hours. |
glioma study 16 (BS-149) / normal astrocyte sample
Relative Expression (log2-ratio):1.6413469Number of Samples:2 / 3
Experimental | glioma study 16 (BS-149) |
Human glioma cell line BS149 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37°C and 5% CO2. | |
Control | normal astrocyte sample |
Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations. |