TOP TEN perturbations for 39655_at (Homo sapiens)
Organism: Homo sapiens
Gene: 39655_at
Selected probe(set): 206367_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 39655_at (206367_at) across 6674 perturbations tested by GENEVESTIGATOR:
IgA nephropathy study 4 (ecap. prolif. pos.) / IgA nephropathy study 4 (ecap. prolif. neg.)
Relative Expression (log2-ratio):-6.903595Number of Samples:2 / 4
Experimental | IgA nephropathy study 4 (ecap. prolif. pos.) |
Glomeruli tissue samples obtained by laser-capture microdissection from kidney biopsies from SLE patients (systemic lupus erythematosus) suffering from IgA nephropathy. The kidney biopsies were reviewed by four neuropathologists in a blinded manner and scored as positive for glomerular endocapillary proliferation (E1 in the Oxford MEST scoring system). (Warning: Experiment with gender bias). | |
Control | IgA nephropathy study 4 (ecap. prolif. neg.) |
Glomeruli tissue samples obtained by laser-capture microdissection from kidney biopsies from SLE patients (systemic lupus erythematosus) suffering from IgA nephropathy. The kidney biopsies were reviewed by four neuropathologists in a blinded manner and scored as negative for glomerular endocapillary proliferation (E0 in the Oxford MEST scoring system). (Warning: Experiment with gender bias). |
renal cell carcinoma study 5 (papillary type) / normal kidney tissue (fetal)
Relative Expression (log2-ratio):-5.964385Number of Samples:19 / 2
Experimental | renal cell carcinoma study 5 (papillary type) |
Tumor tissue samples from the kidney of patients with papillary renal cell carcinoma (pRCC). | |
Control | normal kidney tissue (fetal) |
Normal fetal kidney tissue samples. |
nephroblastoma study 2 / normal kidney tissue (fetal)
Relative Expression (log2-ratio):-5.832514Number of Samples:4 / 2
Experimental | nephroblastoma study 2 |
Tumor tissue samples from the kidney of patients with Wilms’ tumor. | |
Control | normal kidney tissue (fetal) |
Normal fetal kidney tissue samples. |
collecting duct carcinoma study 1 / normal kidney tissue (fetal)
Relative Expression (log2-ratio):-5.4897614Number of Samples:2 / 2
Experimental | collecting duct carcinoma study 1 |
Tumor tissue samples from the kidney of patients with collecting duct carcinoma (CDC). | |
Control | normal kidney tissue (fetal) |
Normal fetal kidney tissue samples. |
renal cell carcinoma study 6 (chromophobe type) / normal kidney tissue (fetal)
Relative Expression (log2-ratio):-5.184744Number of Samples:4 / 2
Experimental | renal cell carcinoma study 6 (chromophobe type) |
Tumor tissue samples from the kidney of patients with chromophobe renal cell carcinoma (cRCC). | |
Control | normal kidney tissue (fetal) |
Normal fetal kidney tissue samples. |
rapidly progressive glomerulonephritis; ANCA-associated vasculitis study 5 (tubulointerstitium) / focal segmental glomerulosclerosis study 9 (glomerulus)
Relative Expression (log2-ratio):-4.4252167Number of Samples:21 / 10
Experimental | rapidly progressive glomerulonephritis; ANCA-associated vasculitis study 5 (tubulointerstitium) |
Tubulointerstitium tissue sample obtained by microdissection from kidney biopsy, from patients suffering from rapidly progressive glomerulonephritis and antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. Donors were positive for ANCA-antibody. Biopsy samples were obtained from the European Renal cDNA Bank-Kroener-Fresenius biopsy bank. All biopsies were stratified by a reference pathologist. | |
Control | focal segmental glomerulosclerosis study 9 (glomerulus) |
Glomeruli tissue sample obtained by microdissection from kidney biopsy, from patients suffering from focal segmental glomerulosclerosis. Biopsy samples were obtained from the European Renal cDNA Bank-Kroener-Fresenius biopsy bank. All biopsies were stratified by a reference pathologist. |
16,16-dimethylprostaglandin E2 study 3 (2h; 10uM; 37°C) / vehicle (DMSO) treated hematopoietic stem cell sample (2h; 37°C)
Relative Expression (log2-ratio):4.218239Number of Samples:7 / 7
Experimental | 16,16-dimethylprostaglandin E2 study 3 (2h; 10uM; 37°C) |
Human CD34+ hematopoietic stem cells treated with 10 uM 16,16-dimethylprostaglandin E2 (dmPGE2) for 2 hours at 37°C. The cells were isolated from umbilical cord blood. ATC code:--- | |
Control | vehicle (DMSO) treated hematopoietic stem cell sample (2h; 37°C) |
Human CD34+ hematopoietic stem cells treated with DMSO for 2 hours at 37°C. The cells were isolated from umbilical cord blood. |
oxyphilic adenoma study 1 / normal kidney tissue (fetal)
Relative Expression (log2-ratio):-4.1872683Number of Samples:4 / 2
Experimental | oxyphilic adenoma study 1 |
Tumor tissue samples from the kidney of patients with oxyphilic adenoma (renal oncocytoma). | |
Control | normal kidney tissue (fetal) |
Normal fetal kidney tissue samples. |
gestational age study 1 (term) / elective termination placenta (1st trim.) tissue
Relative Expression (log2-ratio):-4.096362Number of Samples:4 / 4
Experimental | gestational age study 1 (term) |
Term human placenta samples obtained from scheduled uncomplicated C-sections. | |
Control | elective termination placenta (1st trim.) tissue |
First trimester placenta samples (45-59 days) obtained from uncomplicated elective termination. |
renal cell carcinoma study 4 / normal kidney tissue (fetal)
Relative Expression (log2-ratio):-4.013151Number of Samples:26 / 2
Experimental | renal cell carcinoma study 4 |
Tumor tissue samples from the kidney of patients with renal cell carcinoma (RCC). | |
Control | normal kidney tissue (fetal) |
Normal fetal kidney tissue samples. |