TOP TEN perturbations for 39655_at (Homo sapiens)

Organism: Homo sapiens
Gene: 39655_at
Selected probe(set): 206367_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 39655_at (206367_at) across 6672 perturbations tested by GENEVESTIGATOR:

IgA nephropathy study 4 (ecap. prolif. pos.) / IgA nephropathy study 4 (ecap. prolif. neg.)

Relative Expression (log2-ratio):-6.903595
Number of Samples:2 / 4
Experimental IgA nephropathy study 4 (ecap. prolif. pos.)
Glomeruli tissue samples obtained by laser-capture microdissection from kidney biopsies from SLE patients (systemic lupus erythematosus) suffering from IgA nephropathy. The kidney biopsies were reviewed by four neuropathologists in a blinded manner and scored as positive for glomerular endocapillary proliferation (E1 in the Oxford MEST scoring system). (Warning: Experiment with gender bias).
Control IgA nephropathy study 4 (ecap. prolif. neg.)
Glomeruli tissue samples obtained by laser-capture microdissection from kidney biopsies from SLE patients (systemic lupus erythematosus) suffering from IgA nephropathy. The kidney biopsies were reviewed by four neuropathologists in a blinded manner and scored as negative for glomerular endocapillary proliferation (E0 in the Oxford MEST scoring system). (Warning: Experiment with gender bias).

renal cell carcinoma study 5 (papillary type) / normal kidney tissue

Relative Expression (log2-ratio):-5.964385
Number of Samples:19 / 2
Experimental renal cell carcinoma study 5 (papillary type)
Tumor tissue samples from the kidney of patients with papillary renal cell carcinoma (pRCC).
Control normal kidney tissue
Normal fetal kidney tissue samples.

nephroblastoma study 2 / normal kidney tissue

Relative Expression (log2-ratio):-5.832514
Number of Samples:4 / 2
Experimental nephroblastoma study 2
Tumor tissue samples from the kidney of patients with Wilms’ tumor.
Control normal kidney tissue
Normal fetal kidney tissue samples.

collecting duct carcinoma study 1 / normal kidney tissue

Relative Expression (log2-ratio):-5.4897614
Number of Samples:2 / 2
Experimental collecting duct carcinoma study 1
Tumor tissue samples from the kidney of patients with collecting duct carcinoma (CDC).
Control normal kidney tissue
Normal fetal kidney tissue samples.

renal cell carcinoma study 6 (chromophobe type) / normal kidney tissue

Relative Expression (log2-ratio):-5.184744
Number of Samples:4 / 2
Experimental renal cell carcinoma study 6 (chromophobe type)
Tumor tissue samples from the kidney of patients with chromophobe renal cell carcinoma (cRCC).
Control normal kidney tissue
Normal fetal kidney tissue samples.

rapidly progressive glomerulonephritis; ANCA-associated vasculitis study 5 (tubulointerstitium) / focal segmental glomerulosclerosis study 9 (glomerulus)

Relative Expression (log2-ratio):-4.4252167
Number of Samples:21 / 10
Experimental rapidly progressive glomerulonephritis; ANCA-associated vasculitis study 5 (tubulointerstitium)
Tubulointerstitium tissue sample obtained by microdissection from kidney biopsy, from patients suffering from rapidly progressive glomerulonephritis and antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. Donors were positive for ANCA-antibody. Biopsy samples were obtained from the European Renal cDNA Bank-Kroener-Fresenius biopsy bank. All biopsies were stratified by a reference pathologist.
Control focal segmental glomerulosclerosis study 9 (glomerulus)
Glomeruli tissue sample obtained by microdissection from kidney biopsy, from patients suffering from focal segmental glomerulosclerosis. Biopsy samples were obtained from the European Renal cDNA Bank-Kroener-Fresenius biopsy bank. All biopsies were stratified by a reference pathologist.

16,16-dimethylprostaglandin E2 study 3 (2h; 10uM; 37°C) / vehicle (DMSO) treated hematopoietic stem cell sample (2h; 37°C)

Relative Expression (log2-ratio):4.218239
Number of Samples:7 / 7
Experimental 16,16-dimethylprostaglandin E2 study 3 (2h; 10uM; 37°C)
Human CD34+ hematopoietic stem cells treated with 10 uM 16,16-dimethylprostaglandin E2 (dmPGE2) for 2 hours at 37°C. The cells were isolated from umbilical cord blood. ATC code:---
Control vehicle (DMSO) treated hematopoietic stem cell sample (2h; 37°C)
Human CD34+ hematopoietic stem cells treated with DMSO for 2 hours at 37°C. The cells were isolated from umbilical cord blood.

oxyphilic adenoma study 1 / normal kidney tissue

Relative Expression (log2-ratio):-4.1872683
Number of Samples:4 / 2
Experimental oxyphilic adenoma study 1
Tumor tissue samples from the kidney of patients with oxyphilic adenoma (renal oncocytoma).
Control normal kidney tissue
Normal fetal kidney tissue samples.

gestational age study 1 (term) / elective termination placenta (1st trim.) tissue

Relative Expression (log2-ratio):-4.096362
Number of Samples:4 / 4
Experimental gestational age study 1 (term)
Term human placenta samples obtained from scheduled uncomplicated C-sections.
Control elective termination placenta (1st trim.) tissue
First trimester placenta samples (45-59 days) obtained from uncomplicated elective termination.

renal cell carcinoma study 4 / normal kidney tissue

Relative Expression (log2-ratio):-4.013151
Number of Samples:26 / 2
Experimental renal cell carcinoma study 4
Tumor tissue samples from the kidney of patients with renal cell carcinoma (RCC).
Control normal kidney tissue
Normal fetal kidney tissue samples.