TOP TEN perturbations for 39662_s_at (Homo sapiens)
Organism: Homo sapiens
Gene: 39662_s_at
Selected probe(set): 241989_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 39662_s_at (241989_at) across 6674 perturbations tested by GENEVESTIGATOR:
male infertility study 1 (juvenile; Ad+) / normal testicular lobules tissue (mJS10)
Relative Expression (log2-ratio):-2.1586905Number of Samples:5 / 8
Experimental | male infertility study 1 (juvenile; Ad+) |
Human testicular lobules biopsy samples isolated from prepubescent patients with undescended testes. Testes of these children contained typical level of A-dark (Ad+) spermatogonial cells. | |
Control | normal testicular lobules tissue (mJS10) |
Biopsies of human testicular lobules isolated from fertile vasectomized adult men with normal spermatogenesis. Histological analysis classified samples as mJS10 (modified Johnsen score 10). |
expO ovary cancer study 1 (granulosa cell tumor, malignant; metastatic) / expO ovary cancer study 1 (carcinoma, NOS; metastatic)
Relative Expression (log2-ratio):2.1154737Number of Samples:2 / 5
Experimental | expO ovary cancer study 1 (granulosa cell tumor, malignant; metastatic) |
Metastatic tumor tissue samples obtained from patients with primary granulosa cell tumor of the ovary. | |
Control | expO ovary cancer study 1 (carcinoma, NOS; metastatic) |
Metastatic tumor tissue samples obtained from patients with primary carcinoma (NOS) of the ovary. |
expO ovary cancer study 1 (granulosa cell tumor, malignant; metastatic) / expO ovary cancer study 1 (adenocarcinoma, NOS; metastatic)
Relative Expression (log2-ratio):1.8994169Number of Samples:2 / 7
Experimental | expO ovary cancer study 1 (granulosa cell tumor, malignant; metastatic) |
Metastatic tumor tissue samples obtained from patients with primary granulosa cell tumor of the ovary. | |
Control | expO ovary cancer study 1 (adenocarcinoma, NOS; metastatic) |
Metastatic tumor tissue samples obtained from patients with primary adenocarcinoma (NOS) of the ovary. |
expO ovary cancer study 1 (papillary serous cystadenocarcinoma; metastatic) / expO ovary cancer study 1 (granulosa cell tumor, malignant; metastatic)
Relative Expression (log2-ratio):-1.8785286Number of Samples:51 / 2
Experimental | expO ovary cancer study 1 (papillary serous cystadenocarcinoma; metastatic) |
Metastatic tumor tissue samples obtained from patients with primary papillary serous cystadenocarcinoma of the ovary. | |
Control | expO ovary cancer study 1 (granulosa cell tumor, malignant; metastatic) |
Metastatic tumor tissue samples obtained from patients with primary granulosa cell tumor of the ovary. |
expO ovary cancer study 1 (serous cystadenocarcinoma, NOS; metastatic) / expO ovary cancer study 1 (granulosa cell tumor, malignant; metastatic)
Relative Expression (log2-ratio):-1.8339252Number of Samples:8 / 2
Experimental | expO ovary cancer study 1 (serous cystadenocarcinoma, NOS; metastatic) |
Metastatic tumor tissue samples obtained from patients with primary serous cystadenocarcinoma (NOS) of the ovary. | |
Control | expO ovary cancer study 1 (granulosa cell tumor, malignant; metastatic) |
Metastatic tumor tissue samples obtained from patients with primary granulosa cell tumor of the ovary. |
stem cell differentiation study 59 (iDRG; 12d) / normal embryonic stem cell sample (WA09)
Relative Expression (log2-ratio):1.7807512Number of Samples:4 / 4
Experimental | stem cell differentiation study 59 (iDRG; 12d) |
Immature dorsal root ganglia neurons (iDRGs) obtained by differentiation of WA09 embryonic stem cells. WA09 cells were differentiated for 8 days and subsequently cryopreserved. After thawing, cells were further differentiated for 4 days. Further details are described in the paper. | |
Control | normal embryonic stem cell sample (WA09) |
Undifferentiated WA09 embryonic stem cell samples. |
expO ovary cancer study 1 (granulosa cell tumor, malignant; metastatic) / expO ovary cancer study 1 (clear cell adenocarcinoma, NOS; metastatic)
Relative Expression (log2-ratio):1.7777824Number of Samples:2 / 4
Experimental | expO ovary cancer study 1 (granulosa cell tumor, malignant; metastatic) |
Metastatic tumor tissue samples obtained from patients with primary granulosa cell tumor of the ovary. | |
Control | expO ovary cancer study 1 (clear cell adenocarcinoma, NOS; metastatic) |
Metastatic tumor tissue samples obtained from patients with primary clear cell adenocarcinoma (NOS) of the ovary. |
stem cell differentiation study 59 (iDRG; 15d) / normal embryonic stem cell sample (WA09)
Relative Expression (log2-ratio):1.7545834Number of Samples:4 / 4
Experimental | stem cell differentiation study 59 (iDRG; 15d) |
Immature dorsal root ganglia neurons (iDRGs) obtained by differentiation of WA09 embryonic stem cells. WA09 cells were differentiated for 8 days and subsequently cryopreserved. After thawing, cells were further differentiated for 7 days. Further details are described in the paper. | |
Control | normal embryonic stem cell sample (WA09) |
Undifferentiated WA09 embryonic stem cell samples. |
dengue fever study 10 (DHF) / normal naive CD8 T cell sample
Relative Expression (log2-ratio):1.7464838Number of Samples:2 / 5
Experimental | dengue fever study 10 (DHF) |
Activated CD8 T cells derived from peripheral blood mononuclear cells (PBMCs) of Thai individuals with Dengue hemorrhagic fever (DF) characterized by the WHO 1997. FACS-sorted CD3+, CD8+, HLA_DR+, and CD38+ effector CD8 T subtype cells were used for analysis. | |
Control | normal naive CD8 T cell sample |
Normal naive CD8 T cells derived from peripheral blood mononuclear cells (PBMCs) of healthy Thai individuals. FACS-sorted CD3+, CD8+, CD45RA+, and CCR7+ naive CD8 T subtype cells were used for analysis. |
PGC-1 overexpr. study 1 (WT) / control transfected HEPG2 sample
Relative Expression (log2-ratio):1.7374792Number of Samples:3 / 3
Experimental | PGC-1 overexpr. study 1 (WT) |
HEP-G2 cells infected with adenoviruses carrying a wild-type form of PPARG Coactivator 1 Alpha (PGC-1). Cells were analyzed 24 hours after infection. | |
Control | control transfected HEPG2 sample |
HEp-G2 cells infected with adenoviruses carrying B-galactosidase as a control. Cells were analyzed 24 hours after infection. |