Organism: Homo sapiens
Gene: 39670_at
Selected probe(set): 209940_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 39670_at (209940_at) across 6674 perturbations tested by GENEVESTIGATOR:

Relative Expression (log2-ratio):2.1790571
Number of Samples:2 / 3

Experimental	glioma study 16 (BS-149)
	Human glioma cell line BS149 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37°C and 5% CO2.
Control	normal astrocyte sample
	Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations.

Relative Expression (log2-ratio):2.0955057
Number of Samples:2 / 3

Experimental	glioma study 16 (LN-215)
	Human glioma cell line LN215 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37°C and 5% CO2.
Control	normal astrocyte sample
	Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations.

Relative Expression (log2-ratio):2.012267
Number of Samples:2 / 3

Experimental	glioma study 16 (LN-18)
	Human glioma cell line LN018 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37C and 5% CO2.
Control	normal astrocyte sample
	Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations.

Relative Expression (log2-ratio):1.9052429
Number of Samples:3 / 3

Experimental	IL-1b; IFN-g study 1 (72hrs)
	Pancreatic islets isolated by collagenase digestion from brain-dead organ donors and cultured 3-5 days in RPMI 1640 medium containing 5.6 mM glucose, 10% FCS and 2 mM L-glutamine. Thereafter, islets were cultured in presence of human recombinant IL-1b (25 units/ml) and IFN-g (1,000 units/ml) for 72 hours. Media were changed after 2 days.
Control	untreated pancreatic islet sample (72hrs)
	Untreated pancreatic islets isolated by collagenase digestion from brain-dead organ donors and cultured 3-5 days in RPMI 1640 medium containing 5.6 mM glucose, 10% FCS and 2 mM L-glutamine. Thereafter, islets were cultured in fresh media and harvested after 72 hours. Media were changed after 2 days.

Relative Expression (log2-ratio):1.7236986
Number of Samples:3 / 3

Experimental	IL-1b; IFN-g study 1 (84hrs)
	Pancreatic islets isolated by collagenase digestion from brain-dead organ donors and cultured 3-5 days in RPMI 1640 medium containing 5.6 mM glucose, 10% FCS and 2 mM L-glutamine. Thereafter, islets were cultured in presence of human recombinant IL-1b (25 units/ml) and IFN-g (1,000 units/ml) for 84 hours. Media were changed after 2 days.
Control	untreated pancreatic islet sample (84hrs)
	Untreated pancreatic islets isolated by collagenase digestion from brain-dead organ donors and cultured 3-5 days in RPMI 1640 medium containing 5.6 mM glucose, 10% FCS and 2 mM L-glutamine. Thereafter, islets were cultured in fresh media and harvested after 84 hours. Media were changed after 2 days.

Relative Expression (log2-ratio):1.6831436
Number of Samples:2 / 2

Experimental	IL-1b; IFN-g study 1 (108hrs)
	Pancreatic islets isolated by collagenase digestion from brain-dead organ donors and cultured 3-5 days in RPMI 1640 medium containing 5.6 mM glucose, 10% FCS and 2 mM L-glutamine. Thereafter, islets were cultured in presence of human recombinant IL-1b (25 units/ml) and IFN-g (1,000 units/ml) for 108 hours. Media were changed after 2 and 5 days.
Control	untreated pancreatic islet sample (108hrs)
	Untreated pancreatic islets isolated by collagenase digestion from brain-dead organ donors and cultured 3-5 days in RPMI 1640 medium containing 5.6 mM glucose, 10% FCS and 2 mM L-glutamine. Thereafter, islets were cultured in fresh media and harvested after 108 hours. Media were changed after 2 and 5 days.

Relative Expression (log2-ratio):-1.6255198
Number of Samples:4 / 4

Experimental	OPM-1
	Human primary cancer cell line derived from the peripheral blood of a patient with multiple myeloma. Dexamethasone-resistant. Synonyms:OPM1 Cellosaurus code:
Control	MM1.S
	Human primary cancer cell line derived from the peripheral blood of a patient with multiple myeloma. Dexamethasone-sensitive. Parental cell line:: MM.1 Synonyms:MM.1S; MM1-S; MM-1S; MM1S Cellosaurus code:

Relative Expression (log2-ratio):1.6085186
Number of Samples:3 / 3

Experimental	IL-1b; IFN-g study 1 (60hrs)
	Pancreatic islets isolated by collagenase digestion from brain-dead organ donors and cultured 3-5 days in RPMI 1640 medium containing 5.6 mM glucose, 10% FCS and 2 mM L-glutamine. Thereafter, islets were cultured in presence of human recombinant IL-1b (25 units/ml) and IFN-g (1,000 units/ml) for 60 hours. Media were changed after 2 days.
Control	untreated pancreatic islet sample (60hrs)
	Untreated pancreatic islets isolated by collagenase digestion from brain-dead organ donors and cultured 3-5 days in RPMI 1640 medium containing 5.6 mM glucose, 10% FCS and 2 mM L-glutamine. Thereafter, islets were cultured in fresh media and harvested after 60 hours. Media were changed after 2 days.

Relative Expression (log2-ratio):1.6004267
Number of Samples:8 / 2

Experimental	glioma study 16 (astrocytoma)
	Primary astrocytoma tissues obtained from the operating room. Tumors were diagnosed and graded according to the current WHO classification (grade III-IV).
Control	normal brain tissue
	Normal brain tissue sample from healthy donors.

Relative Expression (log2-ratio):1.57549
Number of Samples:3 / 2

Experimental	glioma study 16 (secondary glioblastoma)
	Secondary glioma tissues obtained from the operating room. Tumors were diagnosed and graded according to the current WHO classification (grade IV).
Control	normal brain tissue
	Normal brain tissue sample from healthy donors.