Organism: Homo sapiens
Gene: 396_f_at
Selected probe(set): 396_f_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 396_f_at (396_f_at) across 6674 perturbations tested by GENEVESTIGATOR:

Relative Expression (log2-ratio):-3.022996
Number of Samples:5 / 6

Experimental	atopic dermatitis study 21 (lesional; whole skin)
	Lesional full thickness skin samples isolated from patient with moderate-to-severe atopic dermatitis by laser capture microdissection. Patients' cohort characteristics: 3 males and 2 females; age 27-59 years (mean age: 39.4 years); SCORing of Atopic Dermatitis index (SCORAD) ranging from 45-65; total IgE: 14-1821 kU/l; eosinophilic count: 1.4-11.8 %.
Control	normal skin tissue
	Full thickness skin samples isolated from healthy subjects by laser capture microdissection.

Relative Expression (log2-ratio):-2.982314
Number of Samples:21 / 10

Experimental	HCC study 27 (young; validation)
	Primary tumor tissue samples obtained from the liver of young patients (≤ 40 years old) with hepatocellular carcinoma assigned to a validation cohort.
Control	HCC study 27 (elder; validation)
	Primary tumor tissue samples obtained from the liver of elder patients (> 40 years old) with hepatocellular carcinoma assigned to a validation cohort.

Relative Expression (log2-ratio):-2.6992245
Number of Samples:5 / 6

Experimental	atopic dermatitis study 21 (non-lesional; whole skin)
	Non-lesional full thickness skin samples isolated from patient with moderate-to-severe atopic dermatitis by laser capture microdissection. Patients' cohort characteristics: 3 males and 2 females; age 27-59 years (mean age: 39.4 years); SCORing of Atopic Dermatitis index (SCORAD) ranging from 45-65; total IgE: 14-1821 kU/l; eosinophilic count: 1.4-11.8 %.
Control	normal skin tissue
	Full thickness skin samples isolated from healthy subjects by laser capture microdissection.

Relative Expression (log2-ratio):2.6296492
Number of Samples:3 / 3

Experimental	CEBP overexpr. study 1
	Primary myometrium myocytes transfected with unspecified CEBP (CCAAT/Enhancer Binding Protein) and harvested after 48 hours. Term myocytes from lower uterine segment were obtained pre-labour from elective caesarean section performed at or after 39 weeks in uncomplicated pregnancies with spontaneously established labor. Indication for caesarean section were cephalopelvic disproportion and risk of fetal hypoxia. None of the patients had received uterotonics. All biopsies were taken by the same surgeon.
Control	empty vector transfected myometrium myocyte sample
	Primary myometrium myocytes transfected with empty vector PSG5 and harvested after 48 hours. Term myocytes from lower uterine segment were obtained pre-labour from elective caesarean section performed at or after 39 weeks in uncomplicated pregnancies with spontaneously established labor. Indication for caesarean section were cephalopelvic disproportion and risk of fetal hypoxia. None of the patients had received uterotonics. All biopsies were taken by the same surgeon.

Relative Expression (log2-ratio):-2.1303034
Number of Samples:11 / 4

Experimental	small cell lung cancer study 4 (XCL from CDX)
	Xenograft-derived cell lines (XCL) established from a small cell lung carcinoma (SCLC) publicly available cell lines derived xenografts (CDX derived cell lines). Xenografts were grown in the flanks of a nude mice. Obtained cells were cultivated under conventional tissue culture conditions.
Control	small cell lung cancer study 4 (cell line)
	Various small cell lung cancer (SCLC) publicly available cell lines samples.

Relative Expression (log2-ratio):-2.0635157
Number of Samples:11 / 6

Experimental	ovarian tumor study 11 (low grade)
	Human microdissected tumor cells from the ovary of patients with low grade serous carcinoma.
Control	normal ovarian surface epithelial cell sample
	Human microdissected ovarian surface epithelial cell sample from the ovary of healthy individuals.

Relative Expression (log2-ratio):-2.0346441
Number of Samples:8 / 12

Experimental	hepatocyte (ESC)
	Hepatocyte-like cells differentiated from embryonic stem cells (ESC)
Control	HepaRG
	Immortalized cancer cell line derived from female patient with hepatocellular carcinoma. Cells can be induced to differentiate into hepatocyte-like cells by exposure to DMSO. Synonyms:Hepa-RG Cellosaurus code:

Relative Expression (log2-ratio):1.9930449
Number of Samples:10 / 32

Experimental	HCC study 27 (elder; validation)
	Primary tumor tissue samples obtained from the liver of elder patients (> 40 years old) with hepatocellular carcinoma assigned to a validation cohort.
Control	HCC study 27 (elder; training)
	Primary tumor tissue samples obtained from the liver of elder patients (> 40 years old) with hepatocellular carcinoma assigned to a training cohort.

Relative Expression (log2-ratio):1.9847136
Number of Samples:4 / 9

Experimental	medulloblastoma study 2
	Primary tumor tissue sample from the infratentorial brain of pediatric patients with large-cell anaplastic medulloblastoma.
Control	non-tumor brain tissue
	Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor.

Relative Expression (log2-ratio):1.8209152
Number of Samples:4 / 23

Experimental	pediatric septic shock study 3 (toddler; subclass A)
	Whole blood samples obtained from toddlers (2 – 5 years) with septic shock subclass A. The samples were obtained within 24 hours of admission to the pediatric intensive care unit. One child did not survive. The subclass A was defined based on an empiric, discovery oriented expression filter and unsupervised hierarchical clustering. Patients in subclass A (when all age groups were pooled) had a significantly higher illness severity level (PRISM III score = 20.5, intra-quartile range (IQR) 12.5 – 32.5), a greater degree of organ failure – maximum number of organ failures 3 (IQR 3 - 4), and a higher mortality rate, a significantly higher incidence of documented Gram-positive bacterial infection and were significantly younger compared with other subclasses.
Control	pediatric septic shock study 3 (toddler)
	Whole blood obtained from toddlers (2 – 5 years) with septic shock. The samples were obtained within 24 hours of admission to the pediatric intensive care unit (day 1). Two children did not survive.