TOP TEN perturbations for 39710_at (Homo sapiens)
Organism: Homo sapiens
Gene: 39710_at
Selected probe(set): 201310_s_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 39710_at (201310_s_at) across 6674 perturbations tested by GENEVESTIGATOR:
glioma study 16 (LN-18) / normal astrocyte sample
Relative Expression (log2-ratio):-5.4045296Number of Samples:2 / 3
Experimental | glioma study 16 (LN-18) |
Human glioma cell line LN018 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37C and 5% CO2. | |
Control | normal astrocyte sample |
Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations. |
azathioprine study 8 (48h) / vehicle (DMSO) treated HepG2 cell sample
Relative Expression (log2-ratio):-5.1322374Number of Samples:2 / 19
Experimental | azathioprine study 8 (48h) |
HepG2 cells exposed to 250μM azathioprine in DMSO solvent for 48 hours. ATC code: | |
Control | vehicle (DMSO) treated HepG2 cell sample |
HepG2 cells exposed to DMSO solvent for 48 hours. |
SKVCR2.0 / SK-OV-3
Relative Expression (log2-ratio):4.9001617Number of Samples:2 / 2
Experimental | SKVCR2.0 |
Human metastatic cancer cell line derived from the ascites of a patent with adenocarcinoma of the ovary. Vincristine-resistant derivative of the ovarian adenocarcinoma cell line SKOV3 capable of growing in media with 2.0 µg/ml vincristine drug. Parental cell line:: SK-OV-3 Synonyms:SKVCR 2.0; SK VCR 2 Cellosaurus code: | |
Control | SK-OV-3 |
Human metastatic cancer cell line derived from the ascites of a patient with ovarian serous cystadenocarcinoma. Synonyms:SKOV-3; SK.OV.3; SKOV3; SKO3 Cellosaurus code: |
renal cell carcinoma study 6 (chromophobe type) / normal kidney tissue (fetal)
Relative Expression (log2-ratio):-4.884136Number of Samples:4 / 2
Experimental | renal cell carcinoma study 6 (chromophobe type) |
Tumor tissue samples from the kidney of patients with chromophobe renal cell carcinoma (cRCC). | |
Control | normal kidney tissue (fetal) |
Normal fetal kidney tissue samples. |
CML study 1 / B-CLL study 5
Relative Expression (log2-ratio):4.658207Number of Samples:75 / 441
Experimental | CML study 1 |
Bone marrow samples of patients with chronic myeloid leukemia (CML). | |
Control | B-CLL study 5 |
Bone marrow samples of patients with B-cell chronic lymphocytic leukemia (B-CLL). |
B-CLL study 5 / normal bone marrow sample
Relative Expression (log2-ratio):-4.6551247Number of Samples:441 / 74
Experimental | B-CLL study 5 |
Bone marrow samples of patients with B-cell chronic lymphocytic leukemia (B-CLL). | |
Control | normal bone marrow sample |
Non-leukemic and healthy bone marrow sample. |
sepsis-ind. mult. organ failure study 1 / normal vastus lateralis muscle tissue
Relative Expression (log2-ratio):-4.3825073Number of Samples:12 / 8
Experimental | sepsis-ind. mult. organ failure study 1 |
Muscle biopsies from patients suffering from sepsis-induced multiple organ failure (MOF), treated in the intensive care unit. Biopsies were obtained from the lateral portion of the vastus lateralis muscle, 10-20 cm above the knee, using a Bergstroem biopsy needle after local anesthesia. At the time of the biopsy, all patients were circulatory stable and not suffering from severe sepsis/septic shock. At the time of biopsy all patients were considered to suffer from multiple organ failure. | |
Control | normal vastus lateralis muscle tissue |
Muscle biopsies from control patients undergoing elective surgery. Biopsies were obtained from the lateral portion of the vastus lateralis muscle, 10-20 cm above the knee, using a Bergstroem biopsy needle just after sedation. |
lung cancer study 1 (PDX; pseudosarcomatous carcinoma; primary) / lung cancer study 1 (PDX; non-small cell carcinoma; primary)
Relative Expression (log2-ratio):4.250082Number of Samples:4 / 2
Experimental | lung cancer study 1 (PDX; pseudosarcomatous carcinoma; primary) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary pseudosarcomatous carcinoma of the lung (subcutaneously implanted). | |
Control | lung cancer study 1 (PDX; non-small cell carcinoma; primary) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary non-small cell carcinoma of the lung (subcutaneously implanted). |
omeprazole study 6 (600uM) / vehicle (DMSO) treated hepatocyte sample
Relative Expression (log2-ratio):-4.161186Number of Samples:2 / 2
Experimental | omeprazole study 6 (600uM) |
Hepatocytes treated with compound: omeprazole (600uM; CHEMBL1503) for 24 hours. ATC code: | |
Control | vehicle (DMSO) treated hepatocyte sample |
Hepatocytes treated with vehicle (DMSO) for 24 hours. |
oxyphilic adenoma study 1 / normal kidney tissue (fetal)
Relative Expression (log2-ratio):-4.14581Number of Samples:4 / 2
Experimental | oxyphilic adenoma study 1 |
Tumor tissue samples from the kidney of patients with oxyphilic adenoma (renal oncocytoma). | |
Control | normal kidney tissue (fetal) |
Normal fetal kidney tissue samples. |