Organism: Homo sapiens
Gene: 39753_at
Selected probe(set): 201389_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 39753_at (201389_at) across 6674 perturbations tested by GENEVESTIGATOR:

Relative Expression (log2-ratio):3.3652267
Number of Samples:12 / 6

Experimental	retina pigment epithelium study 2 (fetal)
	Human cultured fetal retina pigment epithelium samples obtained at gestation age between week 16-18.
Control	retina pigment epithelium study 1 (fetal)
	Human native fetal retina pigment epithelium samples obtained at gestation age between week 16-18.

Relative Expression (log2-ratio):-3.2131586
Number of Samples:9 / 12

Experimental	Hep-G2
	Human primary cancer cell line derived from the liver of a patient with hepatocellular carcinoma. Synonyms:HEP-G2; Hep G2; HEP G2; HepG2; HEPG2 Cellosaurus code:
Control	HepaRG
	Immortalized cancer cell line derived from female patient with hepatocellular carcinoma. Cells can be induced to differentiate into hepatocyte-like cells by exposure to DMSO. Synonyms:Hepa-RG Cellosaurus code:

Relative Expression (log2-ratio):2.8095045
Number of Samples:3 / 4

Experimental	stem cell differentiation study 50 (IRF2 shRNA; ASC; proerythroblast)
	Proerythroblast differentiated from IRF2 (interferon regulatory factor 2) shRNA transduced hematopoietic stem/progenitor cells (CD34+). CD34+ hematopoietic stem/progenitor cells (HSC) were transduced with lentivirus expressing shRNA targeting IRF2 gene with following differentiation to the erythroid lineage. HSCs were obtained from magnetically sorted G-CSF mobilized peripheral blood mononuclear cells of healthy donors. Cells were expanded in StemSpan SFEM medium supplied with Flt-3 ligand (100 ng/ml), SCF (100 ng/ml), IL-3 (20 ng/ml), IL-6 (20 ng/ml) and penicillin/streptomycin. Cells were harvested for total RNA extraction at the proerythroblast stage of differentiation.
Control	stem cell differentiation study 50 (mock shRNA; ASC; proerythroblast)
	Proerythroblast differentiated from control shRNA transduced hematopoietic stem/progenitor cells (CD34+). CD34+ hematopoietic stem/progenitor cells (HSC) were transduced with lentivirus expressing control shRNA with following differentiation to the erythroid lineage. HSCs were obtained from magnetically sorted G-CSF mobilized peripheral blood mononuclear cells of healthy donors. Cells were expanded in StemSpan SFEM medium supplied with Flt-3 ligand (100 ng/ml), SCF (100 ng/ml), IL-3 (20 ng/ml), IL-6 (20 ng/ml) and penicillin/streptomycin. Cells were harvested for total RNA extraction at the proerythroblast stage of differentiation.

Relative Expression (log2-ratio):2.7310104
Number of Samples:2 / 3

Experimental	glioma study 17 (anaplastic astrocytoma; A2B5+)
	Oligodendrocyte progenitor cells (OPC) isolated from high grade anaplastic astrocytoma (grade III). OPC were isolated using magnetic-activated cell sorting (MACS) with antibodies against A2B5 antigen. Patients were 45 ± 18 years old.
Control	non-tumor oligodendrocyte progenitor cell sample (cortex)
	Oligodendrocyte progenitor cells (OPC) isolated from cortical tissue, which was obtained from patients with epilepsy, but without any manifested brain cancer. OPC were isolated using magnetic-activated cell sorting (MACS) with antibodies against A2B5 antigen.

Relative Expression (log2-ratio):2.711403
Number of Samples:3 / 3

Experimental	TGF-β study 11
	HCC827 cells were cultured for 3-5 weeks in the presence of 2ng/ml of TGF-β, to induce epithelial-mesenchymal transition (EMT). 24 hours prior analysis cells were re-seeded without TGF-β.
Control	untreated HCC827 cell sample
	HCC827 cells grown in standard media.

Relative Expression (log2-ratio):-2.6718006
Number of Samples:3 / 3

Experimental	bladder cancer study 1
	Low grade superficial tumor samples.
Control	normal bladder tissue
	Normal bladder tissue.

Relative Expression (log2-ratio):2.6450481
Number of Samples:8 / 60

Experimental	breast cancer study 48 (PDX; metaplastic carcinoma, NOS; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary metaplastic carcinoma, NOS of the breast (subcutaneously implanted).
Control	breast cancer study 48 (PDX; infiltrating duct carcinoma, NOS; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary infiltrating duct carcinoma, NOS of the breast (subcutaneously implanted).

Relative Expression (log2-ratio):2.58677
Number of Samples:3 / 7

Experimental	pancreatic islet study 3 (expanded; NIH)
	Pancreatic islet cells were expanded according to National Institutes of Health (NIH) protocol for 10 weeks. Expansion phase: 2,000 islet equivalents enriched by retention on a 40-μm filter were seeded onto tissue culture–treated dishes in CMRL-1066 medium containing 2 mmol/l l-glutamine and 10% fetal bovine serum.
Control	normal pancreatic islet sample
	Pancreatic islets were obtained from seven donors aged between 37 and 70 years and body mass index between 22 and 27. Functional islets were cultured in CMRL 1066 supplemented with 10% FCS, 1% glutamine, 5.6 mM glucose, 1 mM HEPES, 110 U/ml penicillin, and 110 g/ml streptomycin for 7 days or immediately processed after isolation.

Relative Expression (log2-ratio):2.567666
Number of Samples:8 / 9

Experimental	hepatocyte (ESC)
	Hepatocyte-like cells differentiated from embryonic stem cells (ESC)
Control	Hep-G2
	Human primary cancer cell line derived from the liver of a patient with hepatocellular carcinoma. Synonyms:HEP-G2; Hep G2; HEP G2; HepG2; HEPG2 Cellosaurus code:

Relative Expression (log2-ratio):2.556078
Number of Samples:2 / 22

Experimental	lung cancer study 1 (PDX; non-small cell carcinoma; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary non-small cell carcinoma of the lung (subcutaneously implanted).
Control	lung cancer study 1 (PDX; adenocarcinoma, NOS; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary adenocarcinoma, NOS of the lung (subcutaneously implanted).