TOP TEN perturbations for 39760_at (Homo sapiens)
Organism: Homo sapiens
Gene: 39760_at
Selected probe(set): 212636_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 39760_at (212636_at) across 6674 perturbations tested by GENEVESTIGATOR:
glioma study 16 (LN-319) / normal astrocyte sample
Relative Expression (log2-ratio):-5.9986563Number of Samples:2 / 3
Experimental | glioma study 16 (LN-319) |
Human glioma cell line LN319 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37°C and 5% CO2. | |
Control | normal astrocyte sample |
Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations. |
medulloblastoma study 2 / non-tumor brain tissue
Relative Expression (log2-ratio):-4.581853Number of Samples:4 / 9
Experimental | medulloblastoma study 2 |
Primary tumor tissue sample from the infratentorial brain of pediatric patients with large-cell anaplastic medulloblastoma. | |
Control | non-tumor brain tissue |
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor. |
TC-71 / TC-32
Relative Expression (log2-ratio):4.302088Number of Samples:6 / 6
Experimental | TC-71 |
Human primary cancer cell line derived from the humerus of a patient with Ewing sarcoma. Synonyms:TC71; GM11654 Cellosaurus code: | |
Control | TC-32 |
Human primary cancer cell line derived from the unspecified origin of a patient with Ewing’s sarcoma. Synonyms:TC32 Cellosaurus code: |
atypical teratoid/rhabdoid tumor study 1 / medulloblastoma study 2
Relative Expression (log2-ratio):4.0436716Number of Samples:20 / 4
Experimental | atypical teratoid/rhabdoid tumor study 1 |
Primary tumor tissue sample from the brain of pediatric patients with atypical teratoid/rhabdoid tumor (AT/RT). | |
Control | medulloblastoma study 2 |
Primary tumor tissue sample from the infratentorial brain of pediatric patients with large-cell anaplastic medulloblastoma. |
glioma study 16 (LN-18) / normal astrocyte sample
Relative Expression (log2-ratio):-3.840642Number of Samples:2 / 3
Experimental | glioma study 16 (LN-18) |
Human glioma cell line LN018 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37C and 5% CO2. | |
Control | normal astrocyte sample |
Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations. |
glioma study 16 (LN-229) / normal astrocyte sample
Relative Expression (log2-ratio):-3.7648554Number of Samples:2 / 3
Experimental | glioma study 16 (LN-229) |
Human glioma cell line LN229 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37°C and 5% CO2. | |
Control | normal astrocyte sample |
Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations. |
ovarian tumor study 16 / normal ovarian surface epithelial cell sample
Relative Expression (log2-ratio):-3.7550907Number of Samples:3 / 5
Experimental | ovarian tumor study 16 |
Human epithelial tumor cell samples from the ovary of patients with papillary serous carcinoma. Samples were derived by laser capture microdissection (LCM). | |
Control | normal ovarian surface epithelial cell sample |
Human epithelial cell samples from histopathological normal and non-cancerous ovary tissue. |
renal cell carcinoma study 6 (chromophobe type) / normal kidney tissue (fetal)
Relative Expression (log2-ratio):-3.6718159Number of Samples:4 / 2
Experimental | renal cell carcinoma study 6 (chromophobe type) |
Tumor tissue samples from the kidney of patients with chromophobe renal cell carcinoma (cRCC). | |
Control | normal kidney tissue (fetal) |
Normal fetal kidney tissue samples. |
sangivamycin study 1 / untreated MCF-7 cell sample
Relative Expression (log2-ratio):3.4007368Number of Samples:2 / 2
Experimental | sangivamycin study 1 |
MCF7 cells treated with 2uM sangivamycin for 24 hours. ATC code:--- | |
Control | untreated MCF-7 cell sample |
MCF-7 cells untreated. |
TGF-β study 11 / untreated HCC827 cell sample
Relative Expression (log2-ratio):3.343214Number of Samples:3 / 3
Experimental | TGF-β study 11 |
HCC827 cells were cultured for 3-5 weeks in the presence of 2ng/ml of TGF-β, to induce epithelial-mesenchymal transition (EMT). 24 hours prior analysis cells were re-seeded without TGF-β. | |
Control | untreated HCC827 cell sample |
HCC827 cells grown in standard media. |