TOP TEN perturbations for 39763_at (Homo sapiens)
Organism: Homo sapiens
Gene: 39763_at
Selected probe(set): 39763_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 39763_at (39763_at) across 6674 perturbations tested by GENEVESTIGATOR:
Hep-G2 / HepaRG
Relative Expression (log2-ratio):-5.8877783Number of Samples:9 / 12
Experimental | Hep-G2 |
Human primary cancer cell line derived from the liver of a patient with hepatocellular carcinoma. Synonyms:HEP-G2; Hep G2; HEP G2; HepG2; HEPG2 Cellosaurus code: | |
Control | HepaRG |
Immortalized cancer cell line derived from female patient with hepatocellular carcinoma. Cells can be induced to differentiate into hepatocyte-like cells by exposure to DMSO. Synonyms:Hepa-RG Cellosaurus code: |
hepatoblastoma study 1 (NOS) / normal liver tissue
Relative Expression (log2-ratio):-4.5651436Number of Samples:5 / 5
Experimental | hepatoblastoma study 1 (NOS) |
Liver tumor tissue samples from children with hepatoblastoma (NOS). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group. | |
Control | normal liver tissue |
Normal liver tissue samples. |
hepatoblastoma study 1 (epithelial mixed) / normal liver tissue
Relative Expression (log2-ratio):-4.3847666Number of Samples:12 / 5
Experimental | hepatoblastoma study 1 (epithelial mixed) |
Liver tumor tissue samples from children with hepatoblastoma (epithelial type (E-HB); epithelial mixed subtype). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group. | |
Control | normal liver tissue |
Normal liver tissue samples. |
hepatoblastoma study 1 (embryonal) / normal liver tissue
Relative Expression (log2-ratio):-4.29935Number of Samples:7 / 5
Experimental | hepatoblastoma study 1 (embryonal) |
Liver tumor tissue samples from children with hepatoblastoma (epithelial type (E-HB); embryonal subtype). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group. | |
Control | normal liver tissue |
Normal liver tissue samples. |
hepatocyte (ESC) / Hep-G2
Relative Expression (log2-ratio):4.192361Number of Samples:8 / 9
Experimental | hepatocyte (ESC) |
Hepatocyte-like cells differentiated from embryonic stem cells (ESC) | |
Control | Hep-G2 |
Human primary cancer cell line derived from the liver of a patient with hepatocellular carcinoma. Synonyms:HEP-G2; Hep G2; HEP G2; HepG2; HEPG2 Cellosaurus code: |
hepatoblastoma study 1 (mixed epithelial and mesenchymal) / normal liver tissue
Relative Expression (log2-ratio):-3.935585Number of Samples:4 / 5
Experimental | hepatoblastoma study 1 (mixed epithelial and mesenchymal) |
Liver tumor tissue samples from children with hepatoblastoma (mesenchymal type (MEM-HB); mixed epithelial and mesenchymal subtype). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group. | |
Control | normal liver tissue |
Normal liver tissue samples. |
hepatoblastoma study 1 (crowded fetal) / normal liver tissue
Relative Expression (log2-ratio):-3.8724585Number of Samples:3 / 5
Experimental | hepatoblastoma study 1 (crowded fetal) |
Liver tumor tissue samples from children with hepatoblastoma (epithelial type (E-HB); crowded fetal subtype). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group. | |
Control | normal liver tissue |
Normal liver tissue samples. |
hepatoblastoma study 1 (fetal) / normal liver tissue
Relative Expression (log2-ratio):-3.194397Number of Samples:4 / 5
Experimental | hepatoblastoma study 1 (fetal) |
Liver tumor tissue samples from children with hepatoblastoma (epithelial type (E-HB); fetal subtype). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group. | |
Control | normal liver tissue |
Normal liver tissue samples. |
hepatoblastoma study 1 (mixed embryonal and fetal) / normal liver tissue
Relative Expression (log2-ratio):-3.150895Number of Samples:13 / 5
Experimental | hepatoblastoma study 1 (mixed embryonal and fetal) |
Liver tumor tissue samples from children with hepatoblastoma (epithelial type (E-HB); mixed embryonal and fetal subtype). Tumors were integrase interactor 1–negative (INI1 or SMARCB1) as recommended by the International ConsensusHBClassification group. | |
Control | normal liver tissue |
Normal liver tissue samples. |
HCC study 3 (area A) / HCC study 3 (area C)
Relative Expression (log2-ratio):-2.9551535Number of Samples:13 / 24
Experimental | HCC study 3 (area A) |
Liver tissue biopsy sample from patients with HBV-associated HCC (hepatocellular carcinoma) after orthotopic liver transplantation (OLT) or partial hepatectomy. Tumorous sample was taken from the center of the tumor (area A). Patients were positive for hepatitis B surface antigen, antibody to hepatitis B core antigen and antibody to hepatitis B antigen and received antiviral treatment with nucleos(t)ide analogues prior to surgery. | |
Control | HCC study 3 (area C) |
Liver tissue biopsy sample from patients with HBV-associated HCC (hepatocellular carcinoma) after orthotopic liver transplantation (OLT) or partial hepatectomy. Non-tumorous sample was taken from the perilesional area of the tumor (area C). Patients were positive for hepatitis B surface antigen, antibody to hepatitis B core antigen and antibody to hepatitis B antigen and received antiviral treatment with nucleos(t)ide analogues prior to surgery. |