TOP TEN perturbations for 39765_at (Homo sapiens)

Organism: Homo sapiens
Gene: 39765_at
Selected probe(set): 212701_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 39765_at (212701_at) across 6674 perturbations tested by GENEVESTIGATOR:

breast cancer study 8 (metastatic) / normal breast tissue

Relative Expression (log2-ratio):-3.1944218
Number of Samples:2 / 4
Experimental breast cancer study 8 (metastatic)
Human metastatic infiltrating ductal carcinoma sample of the breast derived from lymph nodes of a female patient with breast cancer.
Control normal breast tissue
Normal human breast samples of healthy female individuals.

breast cancer study 8 (primary) / normal breast tissue

Relative Expression (log2-ratio):-3.0004234
Number of Samples:13 / 4
Experimental breast cancer study 8 (primary)
Human primary infiltrating ductal carcinoma sample of a female patient with breast cancer.
Control normal breast tissue
Normal human breast samples of healthy female individuals.

null cell adenoma study 1 / normal pituitary gland tissue

Relative Expression (log2-ratio):-2.7790203
Number of Samples:2 / 8
Experimental null cell adenoma study 1
Null cell adenoma biopsy samples recovered during transsphenoidal surgery. The tumors were defined by gonadotropic staining for FSH, LH, or alpha subunit in less than 5-10% of cells. Samples were scanned between 04/6/2004 - 15/4/2005.
Control normal pituitary gland tissue
Biopsy samples of healthy pituitary gland recovered post-mortem during autopsy within 2-18 hours of death. Cause of death were mostly various pulmonary or cardiovascular conditions.

medulloblastoma study 1 / non-tumor brain tissue

Relative Expression (log2-ratio):-2.636815
Number of Samples:17 / 9
Experimental medulloblastoma study 1
Primary tumor tissue sample from the infratentorial brain of pediatric patients with classical medulloblastoma.
Control non-tumor brain tissue
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor.

glioma study 16 (LN-18) / normal astrocyte sample

Relative Expression (log2-ratio):-2.4918623
Number of Samples:2 / 3
Experimental glioma study 16 (LN-18)
Human glioma cell line LN018 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37C and 5% CO2.
Control normal astrocyte sample
Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations.

gonadotroph adenoma study 1 / normal pituitary gland tissue

Relative Expression (log2-ratio):-2.442113
Number of Samples:7 / 8
Experimental gonadotroph adenoma study 1
Gonadotroph adenoma biopsy samples recovered during transsphenoidal surgery. The tumors were defined as demonstrating positive immunostaining for FSH, LH, or alpha subunit in greater than 5-10% of cells. Samples were scanned between 04/6/2004 - 15/4/2005.
Control normal pituitary gland tissue
Biopsy samples of healthy pituitary gland recovered post-mortem during autopsy within 2-18 hours of death. Cause of death were mostly various pulmonary or cardiovascular conditions.

brain tumor study 1 (ependymoma) / normal brain tissue

Relative Expression (log2-ratio):-2.4409513
Number of Samples:46 / 12
Experimental brain tumor study 1 (ependymoma)
Primary tumor tissue sample from the brain of patients with ependymoma.
Control normal brain tissue
Histologically normal and non-neoplastic tissue sample from different brain anatomical sites of patients with primary brain tumors.

breast cancer study 16 (mix. inv. dc lc) / adjacent breast tissue

Relative Expression (log2-ratio):-2.4262857
Number of Samples:4 / 27
Experimental breast cancer study 16 (mix. inv. dc lc)
Primary mixed invasive ductal and lobular carcinoma tissue sample derived from the breasts of female patients after surgery.
Control adjacent breast tissue
Histologically normal breast tissue samples obtained from a clinically unaffected site from patients with primary invasive breast cancer.

brain tumor study 1 (medulloblastoma) / normal brain tissue

Relative Expression (log2-ratio):-2.409133
Number of Samples:22 / 12
Experimental brain tumor study 1 (medulloblastoma)
Primary tumor tissue sample from the brain of patients with medulloblastoma.
Control normal brain tissue
Histologically normal and non-neoplastic tissue sample from different brain anatomical sites of patients with primary brain tumors.

breast cancer study 16 (inv. lc) / adjacent breast tissue

Relative Expression (log2-ratio):-2.380786
Number of Samples:5 / 27
Experimental breast cancer study 16 (inv. lc)
Primary invasive lobular carcinoma tissue sample derived from the breasts of female patients after surgery.
Control adjacent breast tissue
Histologically normal breast tissue samples obtained from a clinically unaffected site from patients with primary invasive breast cancer.