TOP TEN perturbations for 39780_at (Homo sapiens)

Organism: Homo sapiens
Gene: 39780_at
Selected probe(set): 202432_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 39780_at (202432_at) across 6674 perturbations tested by GENEVESTIGATOR:

HIV-associated neurocognitive disorder study 7 (normal) / HIV-associated neurocognitive disorder study 6 (normal)

Relative Expression (log2-ratio):2.9088726
Number of Samples:2 / 2
Experimental HIV-associated neurocognitive disorder study 7 (normal)
Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from patients with normal brain pathology. The patients received antiretroviral therapy (ART).
Control HIV-associated neurocognitive disorder study 6 (normal)
Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from patients with normal brain pathology. The patients did not receive any antiretroviral therapy (ART).

glioma study 5 / non-tumor brain tissue

Relative Expression (log2-ratio):-2.7625198
Number of Samples:12 / 9
Experimental glioma study 5
Primary tumor tissue sample from the supratentorial brain of pediatric patients with glioblastoma multiformae.
Control non-tumor brain tissue
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor.

ethionine study 3 (10000uM) / vehicle (medium) treated hepatocyte sample

Relative Expression (log2-ratio):-2.7257843
Number of Samples:2 / 2
Experimental ethionine study 3 (10000uM)
Hepatocytes treated with compound: ethionine (10000uM; CHEMBL203187) for 24 hours. ATC code:---
Control vehicle (medium) treated hepatocyte sample
Hepatocytes treated with vehicle (medium) for 24 hours.

brain tumor study 1 (glioblastoma) / normal brain tissue

Relative Expression (log2-ratio):-2.2887354
Number of Samples:34 / 12
Experimental brain tumor study 1 (glioblastoma)
Primary tumor tissue sample from the brain of patients with glioblastoma multiformae.
Control normal brain tissue
Histologically normal and non-neoplastic tissue sample from different brain anatomical sites of patients with primary brain tumors.

medulloblastoma study 2 / non-tumor brain tissue

Relative Expression (log2-ratio):-2.2613811
Number of Samples:4 / 9
Experimental medulloblastoma study 2
Primary tumor tissue sample from the infratentorial brain of pediatric patients with large-cell anaplastic medulloblastoma.
Control non-tumor brain tissue
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor.

ovarian tumor study 16 / normal ovarian surface epithelial cell sample

Relative Expression (log2-ratio):-2.2537594
Number of Samples:3 / 5
Experimental ovarian tumor study 16
Human epithelial tumor cell samples from the ovary of patients with papillary serous carcinoma. Samples were derived by laser capture microdissection (LCM).
Control normal ovarian surface epithelial cell sample
Human epithelial cell samples from histopathological normal and non-cancerous ovary tissue.

atypical teratoid/rhabdoid tumor study 1 / non-tumor brain tissue

Relative Expression (log2-ratio):-2.2336693
Number of Samples:20 / 9
Experimental atypical teratoid/rhabdoid tumor study 1
Primary tumor tissue sample from the brain of pediatric patients with atypical teratoid/rhabdoid tumor (AT/RT).
Control non-tumor brain tissue
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor.

glioma study 3 / non-tumor brain tissue

Relative Expression (log2-ratio):-2.056202
Number of Samples:81 / 23
Experimental glioma study 3
Primary tumor tissue sample from the brain of patients with glioblastoma multiformae.
Control non-tumor brain tissue
Brain tissue samples from patients with epilepsy and without any manifested brain cancer.

HIV-associated neurocognitive disorder study 7 (normal) / normal genu sample

Relative Expression (log2-ratio):2.029685
Number of Samples:2 / 8
Experimental HIV-associated neurocognitive disorder study 7 (normal)
Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from patients with normal brain pathology. The patients received antiretroviral therapy (ART).
Control normal genu sample
Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from healthy subjects.

glioma study 16 (LN-215) / normal astrocyte sample

Relative Expression (log2-ratio):-1.9469748
Number of Samples:2 / 3
Experimental glioma study 16 (LN-215)
Human glioma cell line LN215 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37°C and 5% CO2.
Control normal astrocyte sample
Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations.