TOP TEN perturbations for 39780_at (Homo sapiens)
Organism: Homo sapiens
Gene: 39780_at
Selected probe(set): 202432_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 39780_at (202432_at) across 6674 perturbations tested by GENEVESTIGATOR:
HIV-associated neurocognitive disorder study 7 (normal) / HIV-associated neurocognitive disorder study 6 (normal)
Relative Expression (log2-ratio):2.9088726Number of Samples:2 / 2
Experimental | HIV-associated neurocognitive disorder study 7 (normal) |
Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from patients with normal brain pathology. The patients received antiretroviral therapy (ART). | |
Control | HIV-associated neurocognitive disorder study 6 (normal) |
Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from patients with normal brain pathology. The patients did not receive any antiretroviral therapy (ART). |
glioma study 5 / non-tumor brain tissue
Relative Expression (log2-ratio):-2.7625198Number of Samples:12 / 9
Experimental | glioma study 5 |
Primary tumor tissue sample from the supratentorial brain of pediatric patients with glioblastoma multiformae. | |
Control | non-tumor brain tissue |
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor. |
ethionine study 3 (10000uM) / vehicle (medium) treated hepatocyte sample
Relative Expression (log2-ratio):-2.7257843Number of Samples:2 / 2
Experimental | ethionine study 3 (10000uM) |
Hepatocytes treated with compound: ethionine (10000uM; CHEMBL203187) for 24 hours. ATC code:--- | |
Control | vehicle (medium) treated hepatocyte sample |
Hepatocytes treated with vehicle (medium) for 24 hours. |
brain tumor study 1 (glioblastoma) / normal brain tissue
Relative Expression (log2-ratio):-2.2887354Number of Samples:34 / 12
Experimental | brain tumor study 1 (glioblastoma) |
Primary tumor tissue sample from the brain of patients with glioblastoma multiformae. | |
Control | normal brain tissue |
Histologically normal and non-neoplastic tissue sample from different brain anatomical sites of patients with primary brain tumors. |
medulloblastoma study 2 / non-tumor brain tissue
Relative Expression (log2-ratio):-2.2613811Number of Samples:4 / 9
Experimental | medulloblastoma study 2 |
Primary tumor tissue sample from the infratentorial brain of pediatric patients with large-cell anaplastic medulloblastoma. | |
Control | non-tumor brain tissue |
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor. |
ovarian tumor study 16 / normal ovarian surface epithelial cell sample
Relative Expression (log2-ratio):-2.2537594Number of Samples:3 / 5
Experimental | ovarian tumor study 16 |
Human epithelial tumor cell samples from the ovary of patients with papillary serous carcinoma. Samples were derived by laser capture microdissection (LCM). | |
Control | normal ovarian surface epithelial cell sample |
Human epithelial cell samples from histopathological normal and non-cancerous ovary tissue. |
atypical teratoid/rhabdoid tumor study 1 / non-tumor brain tissue
Relative Expression (log2-ratio):-2.2336693Number of Samples:20 / 9
Experimental | atypical teratoid/rhabdoid tumor study 1 |
Primary tumor tissue sample from the brain of pediatric patients with atypical teratoid/rhabdoid tumor (AT/RT). | |
Control | non-tumor brain tissue |
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor. |
glioma study 3 / non-tumor brain tissue
Relative Expression (log2-ratio):-2.056202Number of Samples:81 / 23
Experimental | glioma study 3 |
Primary tumor tissue sample from the brain of patients with glioblastoma multiformae. | |
Control | non-tumor brain tissue |
Brain tissue samples from patients with epilepsy and without any manifested brain cancer. |
HIV-associated neurocognitive disorder study 7 (normal) / normal genu sample
Relative Expression (log2-ratio):2.029685Number of Samples:2 / 8
Experimental | HIV-associated neurocognitive disorder study 7 (normal) |
Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from patients with normal brain pathology. The patients received antiretroviral therapy (ART). | |
Control | normal genu sample |
Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from healthy subjects. |
glioma study 16 (LN-215) / normal astrocyte sample
Relative Expression (log2-ratio):-1.9469748Number of Samples:2 / 3
Experimental | glioma study 16 (LN-215) |
Human glioma cell line LN215 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37°C and 5% CO2. | |
Control | normal astrocyte sample |
Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations. |