Organism: Homo sapiens
Gene: 39846_at
Selected probe(set): 203657_s_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 39846_at (203657_s_at) across 6674 perturbations tested by GENEVESTIGATOR:

Relative Expression (log2-ratio):3.0409336
Number of Samples:2 / 2

Experimental	ovarian tumor study 30 (PDX; transitional cell carcinoma, NOS; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary transitional cell carcinoma, NOS of the ovary (subcutaneously implanted).
Control	ovarian tumor study 30 (PDX; adenocarcinoma, NOS; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary adenocarcinoma, NOS of the ovary (subcutaneously implanted).

Relative Expression (log2-ratio):-2.7340775
Number of Samples:9 / 12

Experimental	Hep-G2
	Human primary cancer cell line derived from the liver of a patient with hepatocellular carcinoma. Synonyms:HEP-G2; Hep G2; HEP G2; HepG2; HEPG2 Cellosaurus code:
Control	HepaRG
	Immortalized cancer cell line derived from female patient with hepatocellular carcinoma. Cells can be induced to differentiate into hepatocyte-like cells by exposure to DMSO. Synonyms:Hepa-RG Cellosaurus code:

Relative Expression (log2-ratio):-2.5506668
Number of Samples:8 / 12

Experimental	hepatocyte (ESC)
	Hepatocyte-like cells differentiated from embryonic stem cells (ESC)
Control	HepaRG
	Immortalized cancer cell line derived from female patient with hepatocellular carcinoma. Cells can be induced to differentiate into hepatocyte-like cells by exposure to DMSO. Synonyms:Hepa-RG Cellosaurus code:

Relative Expression (log2-ratio):2.1798992
Number of Samples:2 / 5

Experimental	colorectal cancer study 43 (metastase; brain)
	Metastatic tumor tissue obtained from the brain of patients with primary colorectal adenocarcinoma.
Control	colorectal cancer study 43 (metastase; lung)
	Metastatic tumor tissue obtained from the lung of patients with primary colon adenocarcinoma.

Relative Expression (log2-ratio):2.1775436
Number of Samples:2 / 2

Experimental	ovarian tumor study 30 (PDX; transitional cell carcinoma, NOS; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary transitional cell carcinoma, NOS of the ovary (subcutaneously implanted).
Control	ovarian tumor study 30 (PDX; mixed tumor, malignant, NOS; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary mixed tumor, malignant, NOS of the ovary (subcutaneously implanted).

Relative Expression (log2-ratio):2.1429625
Number of Samples:6 / 2

Experimental	connective/soft tissue cancer study 1 (PDX; connective and soft tissue, synovial sarcoma, spindle cell; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary connective and soft tissue, synovial sarcoma, spindle cell of the soft tissue (subcutaneously implanted).
Control	connective/soft tissue cancer study 1 (PDX; connective and soft tissue, liposarcoma, NOS; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary connective and soft tissue, liposarcoma, NOS of the soft tissue (subcutaneously implanted).

Relative Expression (log2-ratio):2.125183
Number of Samples:2 / 13

Experimental	ovarian tumor study 30 (PDX; transitional cell carcinoma, NOS; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary transitional cell carcinoma, NOS of the ovary (subcutaneously implanted).
Control	ovarian tumor study 30 (PDX; serous cystadenocarcinoma, NOS; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary serous cystadenocarcinoma, NOS of the ovary (subcutaneously implanted).

Relative Expression (log2-ratio):2.1120749
Number of Samples:2 / 2

Experimental	ovarian tumor study 30 (PDX; transitional cell carcinoma, NOS; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary transitional cell carcinoma, NOS of the ovary (subcutaneously implanted).
Control	ovarian tumor study 30 (PDX; clear cell adenocarcinoma, NOS; primary)
	Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary clear cell adenocarcinoma, NOS of the ovary (subcutaneously implanted).

Relative Expression (log2-ratio):2.10956
Number of Samples:2 / 25

Experimental	colorectal cancer study 43 (metastase; brain)
	Metastatic tumor tissue obtained from the brain of patients with primary colorectal adenocarcinoma.
Control	colorectal cancer study 43 (metastase; liver)
	Metastatic tumor tissue obtained from the liver of patients with primary colon adenocarcinoma.

Relative Expression (log2-ratio):2.1049776
Number of Samples:4 / 4

Experimental	GDC-0941 study 1 (3.606 uM)
	A2058 cells treated with 3.606 uM GDC-0941 for 24hours. The concentration corresponding to the IC90 of BKM120. Cells were maintained in DMEM, high glucose, 10% FCS, 1% pyruvate, 2% glutamine. GDC-0941 is a potent inhibitor of PI3Kα/δ, alternative names: [pictilisib] ATC code:---
Control	vehicle (DMSO) treated A2058 cell samples
	A2058 cells treated with vehicle (0.1% DMSO) for 24hours. Cells were maintained in DMEM, high glucose, 10% FCS, 1% pyruvate, 2% glutamine.