Organism: Homo sapiens
Gene: 39857_at
Selected probe(set): 210190_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 39857_at (210190_at) across 6674 perturbations tested by GENEVESTIGATOR:

Relative Expression (log2-ratio):-4.187316
Number of Samples:2 / 5

Experimental	kidney transplantation study 15 (8 week)
	CD14+ monocyte samples derived from kidney transplant patients 8 weeks post-transplantation. Samples were collected 8 week after transplantation and administration of immunosuppressive therapy (day 1-4: methylprednisolone (60 mg); 3 doses: rabbit polyclonal anti-thymocyte globulin (ThymoglobulinH; 6 mg/kg); mycophenolate mofetil (CellCeptH); and tacrolimus (PrografH).
Control	normal monocyte (CD14+) sample
	CD14+ monocyte samples derived from healthy control subjects.

Relative Expression (log2-ratio):-3.7204504
Number of Samples:6 / 12

Experimental	IL-4; GM-CSF study 1 (late)
	Monocytes, cultured with vehicle (DMSO/ethanol) and 500 U/ml IL-4 and 800 U/ml GM-CSF for 5 days. Cytokine treatment was repeated at day 3.
Control	untreated monocyte sample
	Freshly isolated human monocytes from healthy donors.

Relative Expression (log2-ratio):-3.5438843
Number of Samples:58 / 74

Experimental	precursor-B-ALL study 1 (t(12;21)(p12,q22))
	Bone marrow samples of patients with precursor B-ALL (t(12;21)(p12,q22)/TEL-AML1).
Control	normal bone marrow sample
	Non-leukemic and healthy bone marrow sample.

Relative Expression (log2-ratio):-3.3634167
Number of Samples:40 / 74

Experimental	B-ALL study 1 (hyperdiploid)
	Bone marrow samples of patients with hyperdiploid B-ALL (hyperdiploid karyotype).
Control	normal bone marrow sample
	Non-leukemic and healthy bone marrow sample.

Relative Expression (log2-ratio):-3.332327
Number of Samples:36 / 74

Experimental	precursor-B-ALL study 1 (t(1;19)(q23,q13))
	Bone marrow samples of patients with precursor B-ALL (t(1;19)(q23,q13)/E2A-PBX1).
Control	normal bone marrow sample
	Non-leukemic and healthy bone marrow sample.

Relative Expression (log2-ratio):3.1744347
Number of Samples:3 / 3

Experimental	heat shock study 1 (LPS)
	Cultured THP-1 mononuclear cells were treated with heat shock (43°C; 1h) and lipopolysaccharide (1ug/ml; 4h).
Control	untreated THP-1 cell sample
	Cultured THP-1 mononuclear cells were cultured in basal growth media at 37°C.

Relative Expression (log2-ratio):3.1415462
Number of Samples:2 / 2

Experimental	T-cell activation study 2
	CD4+ T-cell samples derived from PBMC´s of HIV-seronegative donors were activated with plate bound CD3 (1ug/ml) and soluble CD28 (50ng/ml) for 2 days..
Control	quiescent CD4+ T-cell sample
	Quiescent CD4+ T-cell samples derived from PBMC´s of HIV-seronegative donors.

Relative Expression (log2-ratio):-3.1088514
Number of Samples:70 / 74

Experimental	precursor-B-ALL study 1 (t(11q23))
	Bone marrow samples of patients with precursor B-ALL (t(11q23)/MLL).
Control	normal bone marrow sample
	Non-leukemic and healthy bone marrow sample.

Relative Expression (log2-ratio):-3.0707598
Number of Samples:232 / 74

Experimental	c-ALL/pre-B-ALL study 1
	Bone marrow samples of patients with c-ALL/pre-B-ALL (without t(9;22)(q34,q11)/BCR-ABL).
Control	normal bone marrow sample
	Non-leukemic and healthy bone marrow sample.

Relative Expression (log2-ratio):-2.9381618
Number of Samples:7 / 12

Experimental	IL-4; GM-CSF study 1 (intermediate)
	Monocytes, cultured with vehicle (DMSO/ethanol) and 500 U/ml IL-4 and 800 U/ml GM-CSF for 24 hours.
Control	untreated monocyte sample
	Freshly isolated human monocytes from healthy donors.