TOP TEN perturbations for 39888_at (Homo sapiens)
Organism: Homo sapiens
Gene: 39888_at
Selected probe(set): 221484_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 39888_at (221484_at) across 6674 perturbations tested by GENEVESTIGATOR:
CML study 1 / B-CLL study 5
Relative Expression (log2-ratio):3.2422905Number of Samples:75 / 441
Experimental | CML study 1 |
Bone marrow samples of patients with chronic myeloid leukemia (CML). | |
Control | B-CLL study 5 |
Bone marrow samples of patients with B-cell chronic lymphocytic leukemia (B-CLL). |
ovarian tumor study 30 (PDX; transitional cell carcinoma, NOS; primary) / ovarian tumor study 30 (PDX; mixed tumor, malignant, NOS; primary)
Relative Expression (log2-ratio):-2.9760036Number of Samples:2 / 2
Experimental | ovarian tumor study 30 (PDX; transitional cell carcinoma, NOS; primary) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary transitional cell carcinoma, NOS of the ovary (subcutaneously implanted). | |
Control | ovarian tumor study 30 (PDX; mixed tumor, malignant, NOS; primary) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary mixed tumor, malignant, NOS of the ovary (subcutaneously implanted). |
B-CLL study 5 / normal bone marrow sample
Relative Expression (log2-ratio):-2.8959427Number of Samples:441 / 74
Experimental | B-CLL study 5 |
Bone marrow samples of patients with B-cell chronic lymphocytic leukemia (B-CLL). | |
Control | normal bone marrow sample |
Non-leukemic and healthy bone marrow sample. |
TNF-ɑ study 20 / normal monocyte sample
Relative Expression (log2-ratio):2.8226805Number of Samples:3 / 7
Experimental | TNF-ɑ study 20 |
Monocyte samples isolated from healthy donors and stimulated in vitro by 100 ng/ml TNFα in whole blood for 1.5 hour. Following stimulation, monocytes were depleted from granulocytes using CD15 MACS beads, and afterwards they were sorted from remaining peripheral blood leukocytes by CD14 labeling. | |
Control | normal monocyte sample |
Monocyte samples isolated from healthy subjects. Peripheral blood monocytes were isolated immediately after drawing blood by depletion from granulocytes using CD15 MACS beads, and afterwards they were sorted from remaining peripheral blood leukocyte by CD14 labeling. |
precursor-B-ALL study 1 (t(11q23)) / normal bone marrow sample
Relative Expression (log2-ratio):-2.8029451Number of Samples:70 / 74
Experimental | precursor-B-ALL study 1 (t(11q23)) |
Bone marrow samples of patients with precursor B-ALL (t(11q23)/MLL). | |
Control | normal bone marrow sample |
Non-leukemic and healthy bone marrow sample. |
c-ALL/pre-B-ALL study 1 / normal bone marrow sample
Relative Expression (log2-ratio):-2.7690697Number of Samples:232 / 74
Experimental | c-ALL/pre-B-ALL study 1 |
Bone marrow samples of patients with c-ALL/pre-B-ALL (without t(9;22)(q34,q11)/BCR-ABL). | |
Control | normal bone marrow sample |
Non-leukemic and healthy bone marrow sample. |
ovarian tumor study 30 (PDX; transitional cell carcinoma, NOS; primary) / ovarian tumor study 30 (PDX; clear cell adenocarcinoma, NOS; primary)
Relative Expression (log2-ratio):-2.732047Number of Samples:2 / 2
Experimental | ovarian tumor study 30 (PDX; transitional cell carcinoma, NOS; primary) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary transitional cell carcinoma, NOS of the ovary (subcutaneously implanted). | |
Control | ovarian tumor study 30 (PDX; clear cell adenocarcinoma, NOS; primary) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary clear cell adenocarcinoma, NOS of the ovary (subcutaneously implanted). |
rheumatoid arthritis study 31 / TNF-ɑ study 20
Relative Expression (log2-ratio):-2.7101097Number of Samples:4 / 3
Experimental | rheumatoid arthritis study 31 |
Monocyte samples isolated from patients with rheumatoid arthritis (RA). Monocytes from whole blood were depleted from granulocytes by CD15 MACS beads, and afterwards they were sorted from remaining peripheral blood leukocytes by CD14 labeling. Patients fulfilled the revised American College of Rheumatology criteria (ACR) for RA. | |
Control | TNF-ɑ study 20 |
Monocyte samples isolated from healthy donors and stimulated in vitro by 100 ng/ml TNFα in whole blood for 1.5 hour. Following stimulation, monocytes were depleted from granulocytes using CD15 MACS beads, and afterwards they were sorted from remaining peripheral blood leukocytes by CD14 labeling. |
T-ALL study 1 / normal bone marrow sample
Relative Expression (log2-ratio):-2.692546Number of Samples:174 / 74
Experimental | T-ALL study 1 |
Bone marrow samples of patients with T-ALL. | |
Control | normal bone marrow sample |
Non-leukemic and healthy bone marrow sample. |
precursor-B-ALL study 1 (t(1;19)(q23,q13)) / normal bone marrow sample
Relative Expression (log2-ratio):-2.6724567Number of Samples:36 / 74
Experimental | precursor-B-ALL study 1 (t(1;19)(q23,q13)) |
Bone marrow samples of patients with precursor B-ALL (t(1;19)(q23,q13)/E2A-PBX1). | |
Control | normal bone marrow sample |
Non-leukemic and healthy bone marrow sample. |