Organism: Homo sapiens
Gene: 39930_at
Selected probe(set): 204718_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 39930_at (204718_at) across 6674 perturbations tested by GENEVESTIGATOR:

Relative Expression (log2-ratio):-5.9366903
Number of Samples:3 / 3

Experimental	wound healing study 2 (ex vivo; DMSO)
	Ex vivo skin samples obtained from healthy donors following reduction surgery of abdomen, and incubated in culture medium containing DMSO for 4 days. To make sure that mainly epidermis was present in the samples, as much dermal tissue as possible was removed by dissection. Skin was sliced into 1x10 mm slices and incubated in keratinocyte medium for four days with 1:1000 fold dilution of DMSO. The cultivation was performed in serum-free keratinocyte medium supplemented with transferrin, hEGF (0.15 ng/mL), 0.5 mg/mL hydrocortisone, gentamicin, amphotericin B, and epinephrine but without insulin.
Control	normal skin tissue (ex vivo)
	Normal skin samples obtained from healthy donors following reduction surgery of abdomen. To make sure that mainly epidermis was present in the samples, as much dermal tissue as possible was removed by dissection.

Relative Expression (log2-ratio):-4.787163
Number of Samples:3 / 3

Experimental	wound healing study 2 (ex vivo; AG1478)
	Ex vivo skin samples obtained from healthy donors following reduction surgery of abdomen, and incubated in culture medium containing AG1478 for 4 days. To make sure that mainly epidermis was present in the samples, as much dermal tissue as possible was removed by dissection. Skin was sliced into 1x10 mm slices and incubated in keratinocyte medium for four days with 10 micromolar AG1478 (dissolved in DMSO). The cultivation was performed in serum-free keratinocyte medium supplemented with transferrin, hEGF (0.15 ng/mL), 0.5 mg/mL hydrocortisone, gentamicin, amphotericin B, and epinephrine but without insulin. AG1478 is EGFR kinase inhibitor. ATC code:---
Control	normal skin tissue (ex vivo)
	Normal skin samples obtained from healthy donors following reduction surgery of abdomen. To make sure that mainly epidermis was present in the samples, as much dermal tissue as possible was removed by dissection.

Relative Expression (log2-ratio):-3.868801
Number of Samples:40 / 2

Experimental	melanoma study 34 (metastatic)
	Metastatic tumor tissue sample obtained from the patients with metastatic malignant melanoma of the skin. Metastatic samples composed of 22 macroscopic lymph node metastases, 16 subcutaneous metastases and 2 solid organ metastases (adrenal and brain).
Control	melanoma study 34 (in situ)
	Tumor tissue from the skin of patients with melanoma in situ.

Relative Expression (log2-ratio):-3.5038939
Number of Samples:15 / 12

Experimental	brain tumor study 1 (pilocytic astrocytoma)
	Primary tumor tissue sample from the brain of patients with pilocytic astrocytoma.
Control	normal brain tissue
	Histologically normal and non-neoplastic tissue sample from different brain anatomical sites of patients with primary brain tumors.

Relative Expression (log2-ratio):3.469925
Number of Samples:2 / 2

Experimental	HIV-associated neurocognitive disorder study 7 (normal)
	Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from patients with normal brain pathology. The patients received antiretroviral therapy (ART).
Control	HIV-associated neurocognitive disorder study 6 (normal)
	Postmortem brain samples of the centrum semiovale (deep white matter) at the coronal level of the genu of the corpus callosum from patients with normal brain pathology. The patients did not receive any antiretroviral therapy (ART).

Relative Expression (log2-ratio):-3.4099417
Number of Samples:9 / 9

Experimental	primitive neuroectodermal tumor study 1
	Primary tumor tissue sample from the supratentorial brain of pediatric patients with primitive neuroectodermal tumor.
Control	non-tumor brain tissue
	Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor.

Relative Expression (log2-ratio):-3.3101835
Number of Samples:6 / 29

Experimental	precursor-B-ALL study 3 (PAX5-rearranged)
	Peripheral blood and bone marrow samples of pediatric patients with precursor B-ALL [dic(9;20)(p11-13;q11) )/PAX5 rearranged]. Patients were part of the Nordic Society Of Pediatric Hematology And Oncology Group (NOPHO).
Control	T-ALL study 3
	Peripheral blood or bone marrow samples of pediatric patients with childhood T-ALL. Patients were part of the Nordic Society Of Pediatric Hematology And Oncology Group (NOPHO).

Relative Expression (log2-ratio):-3.214858
Number of Samples:4 / 6

Experimental	split-thickness skin grafting study 2 (NPWT)
	Skin punch biopsy from patients that underwent split-thickness skin grafting. Sample was taken from the wound site 7 days after grafting. Patients received negative-pressure wound therapy (NPWT) immediately after grafting .
Control	normal skin tissue (skin grafting)
	Skin punch biopsy samples from healthy patients before slit-thickness skin grafting.

Relative Expression (log2-ratio):-3.1322298
Number of Samples:40 / 4

Experimental	melanoma study 34 (metastatic)
	Metastatic tumor tissue sample obtained from the patients with metastatic malignant melanoma of the skin. Metastatic samples composed of 22 macroscopic lymph node metastases, 16 subcutaneous metastases and 2 solid organ metastases (adrenal and brain).
Control	normal skin tissue
	Normal skin tissue.

Relative Expression (log2-ratio):-3.073431
Number of Samples:14 / 2

Experimental	melanoma study 34 (primary)
	Primary tumor tissue from the skin of patients with primary cutaneous melanoma (PCM). PCM consisted of 2 thin melanomas (< 1 mm; T1), 3 intermediate-thickness melanomas (1–4 mm; T2-3), and 9 thick melanomas (> 4 mm; T4).
Control	melanoma study 34 (in situ)
	Tumor tissue from the skin of patients with melanoma in situ.