TOP TEN perturbations for 40012_at (Homo sapiens)
Organism: Homo sapiens
Gene: 40012_at
Selected probe(set): 228955_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 40012_at (228955_at) across 6674 perturbations tested by GENEVESTIGATOR:
expO ovary cancer study 1 (granulosa cell tumor, malignant; metastatic) / expO ovary cancer study 1 (clear cell adenocarcinoma, NOS; metastatic)
Relative Expression (log2-ratio):5.9095917Number of Samples:2 / 4
Experimental | expO ovary cancer study 1 (granulosa cell tumor, malignant; metastatic) |
Metastatic tumor tissue samples obtained from patients with primary granulosa cell tumor of the ovary. | |
Control | expO ovary cancer study 1 (clear cell adenocarcinoma, NOS; metastatic) |
Metastatic tumor tissue samples obtained from patients with primary clear cell adenocarcinoma (NOS) of the ovary. |
expO ovary cancer study 1 (granulosa cell tumor, malignant; metastatic) / expO ovary cancer study 1 (dysgerminoma; metastatic)
Relative Expression (log2-ratio):5.8350077Number of Samples:2 / 2
Experimental | expO ovary cancer study 1 (granulosa cell tumor, malignant; metastatic) |
Metastatic tumor tissue samples obtained from patients with primary granulosa cell tumor of the ovary. | |
Control | expO ovary cancer study 1 (dysgerminoma; metastatic) |
Metastatic tumor tissue samples obtained from patients with primary dysgerminoma of the ovary. |
Merkel cell carcinoma study 3 (primary) / normal skin tissue
Relative Expression (log2-ratio):5.5722437Number of Samples:19 / 64
Experimental | Merkel cell carcinoma study 3 (primary) |
Primary tumor tissue from the skin of patients with Merkel cell carcinoma. | |
Control | normal skin tissue |
Normal skin samples from healthy donors. |
basal cell carcinoma study 2 / normal skin tissue
Relative Expression (log2-ratio):5.3498497Number of Samples:2 / 64
Experimental | basal cell carcinoma study 2 |
Primary tumor tissue from the skin of patients with basal cell carcinoma (BCC). | |
Control | normal skin tissue |
Normal skin samples from healthy donors. |
Merkel cell carcinoma study 3 (metastatic) / normal skin tissue
Relative Expression (log2-ratio):5.299967Number of Samples:11 / 64
Experimental | Merkel cell carcinoma study 3 (metastatic) |
Metastatic tumor tissue from different metastatic sites (skin, lymph node, parotid gland) of patients with Merkel cell carcinoma of the skin. | |
Control | normal skin tissue |
Normal skin samples from healthy donors. |
expO ovary cancer study 1 (serous cystadenocarcinoma, NOS; metastatic) / expO ovary cancer study 1 (granulosa cell tumor, malignant; metastatic)
Relative Expression (log2-ratio):-4.8633614Number of Samples:8 / 2
Experimental | expO ovary cancer study 1 (serous cystadenocarcinoma, NOS; metastatic) |
Metastatic tumor tissue samples obtained from patients with primary serous cystadenocarcinoma (NOS) of the ovary. | |
Control | expO ovary cancer study 1 (granulosa cell tumor, malignant; metastatic) |
Metastatic tumor tissue samples obtained from patients with primary granulosa cell tumor of the ovary. |
expO ovary cancer study 1 (granulosa cell tumor, malignant; metastatic) / expO ovary cancer study 1 (endometrioid carcinoma; metastatic)
Relative Expression (log2-ratio):4.6189356Number of Samples:2 / 3
Experimental | expO ovary cancer study 1 (granulosa cell tumor, malignant; metastatic) |
Metastatic tumor tissue samples obtained from patients with primary granulosa cell tumor of the ovary. | |
Control | expO ovary cancer study 1 (endometrioid carcinoma; metastatic) |
Metastatic tumor tissue samples obtained from patients with primary endometrioid carcinoma of the ovary. |
zalypsis study 2 / untreated OPM1 cell sample
Relative Expression (log2-ratio):-4.5373726Number of Samples:2 / 2
Experimental | zalypsis study 2 |
OPM1 multiple myeloma cells treated in vitro with zalypsis (5 nM), a novel marine-derived compound with potent antimyeloma activity. Cells were harvested at the beginning of induction of cell death (15-20% cell death as assessed by Annexin V-FITC staining). ATC code:--- | |
Control | untreated OPM1 cell sample |
OPM1 multiple myeloma cells untreated. |
ovarian tumor study 30 (PDX; transitional cell carcinoma, NOS; primary) / ovarian tumor study 30 (PDX; serous cystadenocarcinoma, NOS; primary)
Relative Expression (log2-ratio):-4.3041687Number of Samples:2 / 13
Experimental | ovarian tumor study 30 (PDX; transitional cell carcinoma, NOS; primary) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary transitional cell carcinoma, NOS of the ovary (subcutaneously implanted). | |
Control | ovarian tumor study 30 (PDX; serous cystadenocarcinoma, NOS; primary) |
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from patients with primary serous cystadenocarcinoma, NOS of the ovary (subcutaneously implanted). |
expO ovary cancer study 1 (granulosa cell tumor, malignant; metastatic) / expO ovary cancer study 1 (carcinoma, NOS; metastatic)
Relative Expression (log2-ratio):4.293474Number of Samples:2 / 5
Experimental | expO ovary cancer study 1 (granulosa cell tumor, malignant; metastatic) |
Metastatic tumor tissue samples obtained from patients with primary granulosa cell tumor of the ovary. | |
Control | expO ovary cancer study 1 (carcinoma, NOS; metastatic) |
Metastatic tumor tissue samples obtained from patients with primary carcinoma (NOS) of the ovary. |