Organism: Homo sapiens
Gene: 40057_at
Selected probe(set): 205577_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of 40057_at (205577_at) across 6674 perturbations tested by GENEVESTIGATOR:

Relative Expression (log2-ratio):6.8739376
Number of Samples:4 / 2

Experimental	basal cell carcinoma study 3
	Primary tumor tissue from the eyelid of patients with basal cell carcinoma (BCC).
Control	normal epidermal keratinocytes
	Normal human epidermal keratinocytes (NHEK) (Kurabo Ind., Ltd., Osaka, Japan) cultured in HuMedia-KB2 medium at 37°C in humidified air containing 5% CO2.

Relative Expression (log2-ratio):3.8386126
Number of Samples:2 / 13

Experimental	kidney transplantation study 9 (late)
	Human renal allograft biopsies from deceased donors obtained 24 months after transplantation.
Control	normal kidney transplant
	Human renal allograft biopsies from deceased donors obtained at implantation prior to revascularization.

Relative Expression (log2-ratio):3.3265486
Number of Samples:3 / 4

Experimental	R547 study 3 (24h)
	Human prostate carcinoma metastatic cell line DU145 treated with the CDK inhibitor R547 [4-amino-2-(1-methanesulfonylpiperidin-4-ylamino) pyrimidin-5-yl]-(2, 3-difluoro-6-methoxyphenyl)methanone (Hoffmann-La Roche compound) for 24 hours at an IC90 concentration of IC90 = 1.7 μmol/L. ATC code:---
Control	vehicle (DMSO) treated DU145 cell sample
	Human prostate carcinoma metastatic cell line DU145 treated with vehicle (DMSO) for 24 hours.

Relative Expression (log2-ratio):3.071805
Number of Samples:9 / 3

Experimental	myotonic dystrophy study 4 (biceps brachii; DM-like)
	Biceps brachii biopsies obtained from patients with myotonic-like dystrophy (DMx; DM-like; no DMPK or ZNF9 expansion).
Control	normal skeletal muscle tisuue (fetal)
	Commercially purchased normal fetal skeletal muscle tissue samples.

Relative Expression (log2-ratio):3.068059
Number of Samples:3 / 3

Experimental	myotonic dystrophy study 4 (deltoid muscle; DM-like)
	Deltoid muscle biopsies obtained from patients with myotonic-like dystrophy (DMx; DM-like; no DMPK or ZNF9 expansion).
Control	normal skeletal muscle tisuue (fetal)
	Commercially purchased normal fetal skeletal muscle tissue samples.

Relative Expression (log2-ratio):3.0321836
Number of Samples:3 / 3

Experimental	Becker muscular dystrophy study 3 (biceps brachii)
	Biceps brachii biopsies obtained from patients with Becker muscular dystrophy (BMD).
Control	normal skeletal muscle tisuue (fetal)
	Commercially purchased normal fetal skeletal muscle tissue samples.

Relative Expression (log2-ratio):3.01232
Number of Samples:3 / 17

Experimental	dimethyloxalylglycine study 2 (175140ng/ml)
	Bronchial epithelial cells (NHBE) treated with dimethyloxalylglycine (175140ng/ml; vendor: Cayman Chemical / catalog number: CAYM71210-10 / catalog name: dimethyloxallyl glycine) for 6 hours. For treatment primary cells were seeded at a density of 50'000 cells/well in pre-coated rat tail collagen type I 96-well plates for 24 hours followed by 4 hours starvation. NHBE cells were isolated from different Caucasian, healthy and non-smoker donors from the airway located above the bifurcation of the lungs (tracheal/bronchial). ATC code:---
Control	vehicle (DME) treated bronchial epithelial cell sample
	Bronchial epithelial cells (NHBE) treated with vehicle (DME) for 6 hours. For treatment primary cells were seeded at a density of 50'000 cells/well in pre-coated rat tail collagen type I 96-well plates for 24 hours followed by 4 hours starvation. NHBE cells were isolated from different Caucasian, healthy and non-smoker donors from the airway located above the bifurcation of the lungs (tracheal/bronchial).

Relative Expression (log2-ratio):2.9643202
Number of Samples:8 / 3

Experimental	myotonic dystrophy study 4 (skeletal muscle; DM2)
	Unspecified skeletal muscle biopsies obtained from patients with myotonic dystrophy type 2 (DM2).
Control	normal skeletal muscle tisuue (fetal)
	Commercially purchased normal fetal skeletal muscle tissue samples.

Relative Expression (log2-ratio):2.9339018
Number of Samples:2 / 3

Experimental	myotonic dystrophy study 4 (deltoid muscle; DM1)
	Deltoid muscle biopsies obtained from patients with myotonic dystrophy type 1 (DM1).
Control	normal skeletal muscle tisuue (fetal)
	Commercially purchased normal fetal skeletal muscle tissue samples.

Relative Expression (log2-ratio):2.8361044
Number of Samples:3 / 3

Experimental	myotonic dystrophy study 4 (biceps brachii; DM1)
	Biceps brachii biopsies obtained from patients with myotonic dystrophy type 1 (DM1).
Control	normal skeletal muscle tisuue (fetal)
	Commercially purchased normal fetal skeletal muscle tissue samples.