TOP TEN perturbations for 40074_at (Homo sapiens)
Organism: Homo sapiens
Gene: 40074_at
Selected probe(set): 201761_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of 40074_at (201761_at) across 6674 perturbations tested by GENEVESTIGATOR:
Hep-G2 / HepaRG
Relative Expression (log2-ratio):7.693573Number of Samples:9 / 12
Experimental | Hep-G2 |
Human primary cancer cell line derived from the liver of a patient with hepatocellular carcinoma. Synonyms:HEP-G2; Hep G2; HEP G2; HepG2; HEPG2 Cellosaurus code: | |
Control | HepaRG |
Immortalized cancer cell line derived from female patient with hepatocellular carcinoma. Cells can be induced to differentiate into hepatocyte-like cells by exposure to DMSO. Synonyms:Hepa-RG Cellosaurus code: |
hepatocyte (ESC) / HepaRG
Relative Expression (log2-ratio):7.1824207Number of Samples:8 / 12
Experimental | hepatocyte (ESC) |
Hepatocyte-like cells differentiated from embryonic stem cells (ESC) | |
Control | HepaRG |
Immortalized cancer cell line derived from female patient with hepatocellular carcinoma. Cells can be induced to differentiate into hepatocyte-like cells by exposure to DMSO. Synonyms:Hepa-RG Cellosaurus code: |
T-cell activation study 4 / normal resting T-cell sample
Relative Expression (log2-ratio):4.8276787Number of Samples:2 / 2
Experimental | T-cell activation study 4 |
T-cell samples antiCD3 activated for 30hrs. | |
Control | normal resting T-cell sample |
T cells resting for 30h. |
glioma study 27 (astrocytoma, NOS) / glioma study 27 (pilocytic astrocytoma)
Relative Expression (log2-ratio):4.7212973Number of Samples:5 / 2
Experimental | glioma study 27 (astrocytoma, NOS) |
Primary tumor samples from resected brain tissues of patients with astrocytoma, NOS (WHO grade II astrocytoma). | |
Control | glioma study 27 (pilocytic astrocytoma) |
Primary tumor samples from resected brain tissues of patients with pilocytic astrocytoma (WHO grade I astrocytoma). |
retina pigment epithelium study 2 (fetal) / retina pigment epithelium study 1 (fetal)
Relative Expression (log2-ratio):4.092107Number of Samples:12 / 6
Experimental | retina pigment epithelium study 2 (fetal) |
Human cultured fetal retina pigment epithelium samples obtained at gestation age between week 16-18. | |
Control | retina pigment epithelium study 1 (fetal) |
Human native fetal retina pigment epithelium samples obtained at gestation age between week 16-18. |
T-cell activation study 1 / quiescent CD4+ T-cell sample
Relative Expression (log2-ratio):3.9308128Number of Samples:2 / 2
Experimental | T-cell activation study 1 |
CD4+ T-cell samples derived from PBMC´s of HIV-seronegative donors were activated with plate bound CD3 (1ug/ml) and soluble CD28 (50ng/ml) for 1 day. | |
Control | quiescent CD4+ T-cell sample |
Quiescent CD4+ T-cell samples derived from PBMC´s of HIV-seronegative donors. |
glioma study 16 (secondary glioblastoma) / normal brain tissue
Relative Expression (log2-ratio):3.871069Number of Samples:3 / 2
Experimental | glioma study 16 (secondary glioblastoma) |
Secondary glioma tissues obtained from the operating room. Tumors were diagnosed and graded according to the current WHO classification (grade IV). | |
Control | normal brain tissue |
Normal brain tissue sample from healthy donors. |
glioma study 16 (astrocytoma) / normal brain tissue
Relative Expression (log2-ratio):3.8703127Number of Samples:8 / 2
Experimental | glioma study 16 (astrocytoma) |
Primary astrocytoma tissues obtained from the operating room. Tumors were diagnosed and graded according to the current WHO classification (grade III-IV). | |
Control | normal brain tissue |
Normal brain tissue sample from healthy donors. |
memory T-cell activation study 1 / untreated memory CD4 T-cell sample
Relative Expression (log2-ratio):3.8465033Number of Samples:3 / 3
Experimental | memory T-cell activation study 1 |
Memory (CD45RA-) CD4+ T-cells isolated from peripheral blood of healthy female donors were activated with anti-CD3/CD28 beads for 24hrs. | |
Control | untreated memory CD4 T-cell sample |
Memory (CD45RA-) CD4+ T-cells were isolated from peripheral blood of healthy female donors and incubated in X-VIVO 20 medium for 24 hours, before harvest for RNA isolation. |
glioma study 16 (oligodendroglioma) / normal brain tissue
Relative Expression (log2-ratio):3.6765041Number of Samples:7 / 2
Experimental | glioma study 16 (oligodendroglioma) |
Primary oligodendroglioma tissues obtained from the operating room. Tumors were diagnosed and graded according to the current WHO classification (grade OGII-III). | |
Control | normal brain tissue |
Normal brain tissue sample from healthy donors. |