TOP TEN perturbations for MTURN (Homo sapiens)
Organism: Homo sapiens
Gene: MTURN
Selected probe(set): 226018_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array
Expression of MTURN (226018_at) across 6540 perturbations tested by GENEVESTIGATOR:
renal cell carcinoma study 1 (metastasis) / adjacent kidney tissue
Relative Expression (log2-ratio):-4.3457108Number of Samples:3 / 3
Experimental | renal cell carcinoma study 1 (metastasis) |
Tumor tissue from metastases of patients with renal cell carcinoma (RCC). | |
Control | adjacent kidney tissue |
Histologically normal tissue from an unaffected site (renal tubules) of patients with renal cell carcinoma (RCC) of the clear cell type. |
renal cell carcinoma study 1 (prim. tumor) / adjacent kidney tissue
Relative Expression (log2-ratio):-4.1576624Number of Samples:3 / 3
Experimental | renal cell carcinoma study 1 (prim. tumor) |
Tumor tissue from the primary tumor of patients with renal cell carcinoma (RCC). | |
Control | adjacent kidney tissue |
Histologically normal tissue from an unaffected site (renal tubules) of patients with renal cell carcinoma (RCC) of the clear cell type. |
glioma study 17 (glioblastoma; unsorted) / non-tumor cortical tissue
Relative Expression (log2-ratio):-3.972744Number of Samples:2 / 4
Experimental | glioma study 17 (glioblastoma; unsorted) |
Brain cells isolated from high grade glioblastoma (grade IV). Tumor tissue was dissociated using enzymatic treatment and all cells were used for RNA isolation. | |
Control | non-tumor cortical tissue |
Cortical tissue obtained from patients with epilepsy, but without any manifested brain cancer. The tissue was dissociated using enzymatic treatment, but all brain cell types were used for analyses. |
CD44s overexpr. study 1 / normal HEK-293 cell sample
Relative Expression (log2-ratio):-3.7599268Number of Samples:3 / 3
Experimental | CD44s overexpr. study 1 |
Human embryonic kidney cell line HEK-293 transfected with pcDNA3.1(-) vector containing codon-optimized human CD44 sequence for expression. | |
Control | normal HEK-293 cell sample |
Untransfected, native human embryonic kidney cell line HEK-293 cell samples. |
stem cell differentiation study 59 (iDRG; 15d) / stem cell differentiation study 59 (8d)
Relative Expression (log2-ratio):3.712966Number of Samples:4 / 4
Experimental | stem cell differentiation study 59 (iDRG; 15d) |
Immature dorsal root ganglia neurons (iDRGs) obtained by differentiation of WA09 embryonic stem cells. WA09 cells were differentiated for 8 days and subsequently cryopreserved. After thawing, cells were further differentiated for 7 days. Further details are described in the paper. | |
Control | stem cell differentiation study 59 (8d) |
WA09 embryonic stem cell samples differentiated for 8 days. Further details are described in the paper. |
breast cancer study 16 (inv. dc) / adjacent breast tissue
Relative Expression (log2-ratio):-3.712926Number of Samples:22 / 27
Experimental | breast cancer study 16 (inv. dc) |
Primary invasive ductal carcinoma tissue sample derived from the breasts of female patients after surgery. | |
Control | adjacent breast tissue |
Histologically normal breast tissue samples obtained from a clinically unaffected site from patients with primary invasive breast cancer. |
stem cell differentiation study 59 (iDRG; 15d) / stem cell differentiation study 59 (iDRG; 9d)
Relative Expression (log2-ratio):3.661501Number of Samples:4 / 4
Experimental | stem cell differentiation study 59 (iDRG; 15d) |
Immature dorsal root ganglia neurons (iDRGs) obtained by differentiation of WA09 embryonic stem cells. WA09 cells were differentiated for 8 days and subsequently cryopreserved. After thawing, cells were further differentiated for 7 days. Further details are described in the paper. | |
Control | stem cell differentiation study 59 (iDRG; 9d) |
Immature dorsal root ganglia neurons (iDRGs) obtained by differentiation of WA09 embryonic stem cells. WA09 cells were differentiated for 8 days and subsequently cryopreserved. After thawing, cells were further differentiated for 1 day. Further details are described in the paper. |
stem cell differentiation study 59 (iDRG; 15d) / normal embryonic stem cell sample (WA09)
Relative Expression (log2-ratio):3.609847Number of Samples:4 / 4
Experimental | stem cell differentiation study 59 (iDRG; 15d) |
Immature dorsal root ganglia neurons (iDRGs) obtained by differentiation of WA09 embryonic stem cells. WA09 cells were differentiated for 8 days and subsequently cryopreserved. After thawing, cells were further differentiated for 7 days. Further details are described in the paper. | |
Control | normal embryonic stem cell sample (WA09) |
Undifferentiated WA09 embryonic stem cell samples. |
atypical teratoid/rhabdoid tumor study 1 / non-tumor brain tissue
Relative Expression (log2-ratio):-3.588273Number of Samples:20 / 9
Experimental | atypical teratoid/rhabdoid tumor study 1 |
Primary tumor tissue sample from the brain of pediatric patients with atypical teratoid/rhabdoid tumor (AT/RT). | |
Control | non-tumor brain tissue |
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor. |
renal cell carcinoma study 4 / normal kidney tissue
Relative Expression (log2-ratio):-3.5323915Number of Samples:26 / 3
Experimental | renal cell carcinoma study 4 |
Tumor tissue samples from the kidney of patients with renal cell carcinoma (RCC). | |
Control | normal kidney tissue |
Normal adult kidney tissue samples. |