Organism: Homo sapiens
Gene: ZNF414
Selected probe(set): 227071_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of ZNF414 (227071_at) across 6540 perturbations tested by GENEVESTIGATOR:

Relative Expression (log2-ratio):-1.252634
Number of Samples:2 / 3

Experimental	stem cell differentiation study 41 (hES-T3 EB)
	Sample of embryonic bodies (EB) differentiated from human embryonic stem cells T3 with female karyotype.
Control	undifferentiated hES-T3 cell sample
	Undifferentiated human embryonic stem cells T3.

Relative Expression (log2-ratio):-1.1867647
Number of Samples:2 / 3

Experimental	brefeldin A study 1 (0.5ug/ml; p53HCT116)
	Derived human colon carcinoma cell line p53HCT116 with knockout gene for p53 was treated with 0.5 ug/ml brefeldin-A for 24 hours in McCOYs 5A medium supplemented with 10% heat inactivated FBS. ATC code:---
Control	untreated p53HCT116 cell sample
	Derived human colon carcinoma cell line p53HCT116 with knockout gene for p53 was grown in McCOYs 5A medium supplemented with 10% heat inactivated FBS.

Relative Expression (log2-ratio):1.0665016
Number of Samples:10 / 4

Experimental	Langerhans cell histiocytosis study 3
	CD3+ T-lymphocyte samples isolated from Langerhans cell histiocytosis (LCH) lesions in bone (8 cases) or skin (2 cases). Patient with different clinical status were included in this study (unifocal, single system; multifocal, single system and multifocal, multisystem disease).
Control	normal tonsillar T-lymphocyte sample
	Normal tonsillar CD3+ T-lymphocytes were isolated from children who undergone elective tonsillectomy. The T-cells were isolated from presumably healthy tissue.

Relative Expression (log2-ratio):1.0227256
Number of Samples:2 / 3

Experimental	glioma study 16 (LN-215)
	Human glioma cell line LN215 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37°C and 5% CO2.
Control	normal astrocyte sample
	Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations.

Relative Expression (log2-ratio):-0.90876675
Number of Samples:3 / 3

Experimental	tunicamycin study 2 (2ug/ml; HCT 116)
	Human colon carcinoma cell line HCT116 was treated with 2 ug/ml tunicamycin for 24 hours in McCOYs 5A medium supplemented with 10% heat inactivated FBS. ATC code:---
Control	untreated HCT 116 cell sample
	Human colon carcinoma cell line HCT116 was grown in McCOYs 5A medium supplemented with 10% heat inactivated FBS.

Relative Expression (log2-ratio):-0.90349865
Number of Samples:4 / 2

Experimental	basal cell carcinoma study 3
	Primary tumor tissue from the eyelid of patients with basal cell carcinoma (BCC).
Control	normal epidermal keratinocytes
	Normal human epidermal keratinocytes (NHEK) (Kurabo Ind., Ltd., Osaka, Japan) cultured in HuMedia-KB2 medium at 37°C in humidified air containing 5% CO2.

Relative Expression (log2-ratio):0.90104675
Number of Samples:3 / 7

Experimental	4-nitro-o-phenylenediamine study 1 (24h)
	HepG2 cells exposed to 2mM 4-nitro-o-phenylenediamine in DMSO solvent for 24 hours. ATC code:---
Control	vehicle (DMSO) treated HepG2 cell sample
	HepG2 cells exposed to DMSO solvent for 24 hours.

Relative Expression (log2-ratio):0.8879967
Number of Samples:3 / 3

Experimental	diclofenac study 7 (24h)
	HepG2 cells exposed to 100μM diclofenac in PBS solvent for 24 hours. ATC code:, ,
Control	vehicle (PBS) treated HepG2 cell sample
	HepG2 cells exposed to 0.5% PBS solvent for 24 hours.

Relative Expression (log2-ratio):0.86396074
Number of Samples:2 / 3

Experimental	glioma study 16 (LN-319)
	Human glioma cell line LN319 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37°C and 5% CO2.
Control	normal astrocyte sample
	Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations.

Relative Expression (log2-ratio):-0.86325455
Number of Samples:3 / 3

Experimental	brefeldin A study 1 (0.5ug/ml; HCT 116)
	Human colon carcinoma cell line HCT116 was treated with 0.5 ug/ml brefeldin-A for 24 hours in McCOYs 5A medium supplemented with 10% heat inactivated FBS. ATC code:---
Control	untreated HCT 116 cell sample
	Human colon carcinoma cell line HCT116 was grown in McCOYs 5A medium supplemented with 10% heat inactivated FBS.