TOP TEN perturbations for NM_000055 (Homo sapiens)

Organism: Homo sapiens
Gene: NM_000055
Selected probe(set): 205433_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of NM_000055 (205433_at) across 5392 perturbations tested by GENEVESTIGATOR:

Alagille syndrome study 1 / Roberts syndrome study 1

Relative Expression (log2-ratio):-6.3946133
Number of Samples:2 / 2
Experimental Alagille syndrome study 1
Lymphoblastoid cell line samples from probands with Alagille syndrome (AGS).
Control Roberts syndrome study 1
Lymphoblastoid cell line samples from probands with Roberts syndrome (RBS).

ovarian tumor study 17 / normal ovarian surface epithelial cell sample

Relative Expression (log2-ratio):-6.3567533
Number of Samples:9 / 10
Experimental ovarian tumor study 17
Human epithelial tumor cell samples from the ovary of patients with primary clear cell carcinoma. Samples were derived by laser capture microdissection (LCM).
Control normal ovarian surface epithelial cell sample
Human epithelial cell samples from histopathological normal and non-cancerous ovary tissue from donors with non-cancerous, benign gynecological diseases.

PARK2 overexpression study 1 / control transfected U251 cell sample

Relative Expression (log2-ratio):6.076937
Number of Samples:3 / 3
Experimental PARK2 overexpression study 1
Human brain glioma cell line U-251MG overexpressing ectopic wild-type PARK2 (parkin RBR E3 ubiquitin protein ligase). For generation of a stable cell line, the cells were infected with viral particles in the presence of 8 ug/mL polybrene followed by puromycin selection.
Control control transfected U251 cell sample
Human brain glioma cell line U-251MG with stable GFP expression. For generation of a cell line, the cells were infected with viral particles in the presence of 8 ug/mL polybrene followed by puromycin selection.

ovarian tumor study 11 (borderline) / normal ovarian surface epithelial cell sample

Relative Expression (log2-ratio):-6.0566216
Number of Samples:8 / 6
Experimental ovarian tumor study 11 (borderline)
Human microdissected tumor cells from the ovary of patients with low-malignant (borderline) tumors of the ovary.
Control normal ovarian surface epithelial cell sample
Human microdissected ovarian surface epithelial cell sample from the ovary of healthy individuals.

ovarian tumor study 16 / normal ovarian surface epithelial cell sample

Relative Expression (log2-ratio):-6.011015
Number of Samples:3 / 5
Experimental ovarian tumor study 16
Human epithelial tumor cell samples from the ovary of patients with papillary serous carcinoma. Samples were derived by laser capture microdissection (LCM).
Control normal ovarian surface epithelial cell sample
Human epithelial cell samples from histopathological normal and non-cancerous ovary tissue.

Roberts syndrome study 1 / normal lymphoblastoid cell line sample

Relative Expression (log2-ratio):5.931961
Number of Samples:2 / 18
Experimental Roberts syndrome study 1
Lymphoblastoid cell line samples from probands with Roberts syndrome (RBS).
Control normal lymphoblastoid cell line sample
Lymphoblastoid cell line samples from healthy subjects.

Hep-G2 / HepaRG

Relative Expression (log2-ratio):-5.885646
Number of Samples:9 / 12
Experimental Hep-G2
Human primary cancer cell line derived from the liver of a patient with hepatocellular carcinoma. Synonyms:HEP-G2; Hep G2; HEP G2; HepG2; HEPG2 Cellosaurus code:
Control HepaRG
Immortalized cancer cell line derived from female patient with hepatocellular carcinoma. Cells can be induced to differentiate into hepatocyte-like cells by exposure to DMSO. Synonyms:Hepa-RG Cellosaurus code:

HBV-related HCC study 1 / adjacent HBV-related liver tissue (CH)

Relative Expression (log2-ratio):-5.76206
Number of Samples:5 / 4
Experimental HBV-related HCC study 1
Hepatitis B infection related human hepatocellular carcinoma sample.
Control adjacent HBV-related liver tissue (CH)
Histologically normal adjacent liver tissue of a patient with Hepatitis B infection related hepatocellular carcinoma. Patient with chronic hepatitis.

ovarian tumor study 11 (low grade) / normal ovarian surface epithelial cell sample

Relative Expression (log2-ratio):-5.689537
Number of Samples:11 / 6
Experimental ovarian tumor study 11 (low grade)
Human microdissected tumor cells from the ovary of patients with low grade serous carcinoma.
Control normal ovarian surface epithelial cell sample
Human microdissected ovarian surface epithelial cell sample from the ovary of healthy individuals.

ovarian tumor study 13 / normal ovarian surface epithelial cell sample

Relative Expression (log2-ratio):-5.608425
Number of Samples:18 / 12
Experimental ovarian tumor study 13
Human epithelial tumor cell samples from the ovary of patients with serous adenocarcinoma. Samples were derived by laser capture microdissection (LCM).
Control normal ovarian surface epithelial cell sample
Human epithelial cell samples from histopathological normal and non-cancerous ovary tissue from healthy donors. Samples were derived by cell surface brushing.