TOP TEN perturbations for NM_000085 (Homo sapiens)

Organism: Homo sapiens
Gene: NM_000085
Selected probe(set): 205985_x_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of NM_000085 (205985_x_at) across 5392 perturbations tested by GENEVESTIGATOR:

nephroblastoma study 2 / normal kidney tissue

Relative Expression (log2-ratio):-3.9505777
Number of Samples:4 / 3
Experimental nephroblastoma study 2
Tumor tissue samples from the kidney of patients with Wilms? tumor.
Control normal kidney tissue
Normal adult kidney tissue samples.

renal cell carcinoma study 4 / normal kidney tissue

Relative Expression (log2-ratio):-3.940053
Number of Samples:26 / 3
Experimental renal cell carcinoma study 4
Tumor tissue samples from the kidney of patients with renal cell carcinoma (RCC).
Control normal kidney tissue
Normal adult kidney tissue samples.

clear cell renal cell carcinoma study 4 (stage 3) / normal kidney tissue

Relative Expression (log2-ratio):-3.8811502
Number of Samples:14 / 69
Experimental clear cell renal cell carcinoma study 4 (stage 3)
Primary tumor tissue from patients with stage 3 clear cell renal cell carcinoma (ccRCC).
Control normal kidney tissue
Normal kidney tissue samples obtained from healthy individuals.

clear cell renal cell carcinoma study 4 (stage 2) / normal kidney tissue

Relative Expression (log2-ratio):-3.754838
Number of Samples:19 / 69
Experimental clear cell renal cell carcinoma study 4 (stage 2)
Primary tumor tissue from patients with stage 2 clear cell renal cell carcinoma (ccRCC).
Control normal kidney tissue
Normal kidney tissue samples obtained from healthy individuals.

renal cell carcinoma study 6 (chromophobe type) / normal kidney tissue

Relative Expression (log2-ratio):3.681819
Number of Samples:4 / 2
Experimental renal cell carcinoma study 6 (chromophobe type)
Tumor tissue samples from the kidney of patients with chromophobe renal cell carcinoma (cRCC).
Control normal kidney tissue
Normal fetal kidney tissue samples.

collecting duct carcinoma study 1 / normal kidney tissue

Relative Expression (log2-ratio):-3.6632395
Number of Samples:2 / 3
Experimental collecting duct carcinoma study 1
Tumor tissue samples from the kidney of patients with collecting duct carcinoma (CDC).
Control normal kidney tissue
Normal adult kidney tissue samples.

renal cell carcinoma study 5 (papillary type) / normal kidney tissue

Relative Expression (log2-ratio):-3.587963
Number of Samples:19 / 3
Experimental renal cell carcinoma study 5 (papillary type)
Tumor tissue samples from the kidney of patients with papillary renal cell carcinoma (pRCC).
Control normal kidney tissue
Normal adult kidney tissue samples.

clear cell renal cell carcinoma study 4 (stage 4) / normal kidney tissue

Relative Expression (log2-ratio):-3.3994656
Number of Samples:14 / 69
Experimental clear cell renal cell carcinoma study 4 (stage 4)
Primary tumor tissue from patients with stage 4 clear cell renal cell carcinoma (ccRCC).
Control normal kidney tissue
Normal kidney tissue samples obtained from healthy individuals.

clear cell renal cell carcinoma study 4 (stage 1) / normal kidney tissue

Relative Expression (log2-ratio):-3.3133125
Number of Samples:23 / 69
Experimental clear cell renal cell carcinoma study 4 (stage 1)
Primary tumor tissue from patients with stage 1 clear cell renal cell carcinoma (ccRCC).
Control normal kidney tissue
Normal kidney tissue samples obtained from healthy individuals.

clear cell renal cell carcinoma study 3 (non-obese; smoker) / smoking study 71 (non-obese)

Relative Expression (log2-ratio):-3.2142105
Number of Samples:16 / 15
Experimental clear cell renal cell carcinoma study 3 (non-obese; smoker)
Tumor tissue from patients with clear cell renal cell carcinoma (ccRCC). Patients were smokers and had a BMI < 30 kg/m2. Patients with late T4 stage and grade 4 tumors were excluded.
Control smoking study 71 (non-obese)
Kidney tissue samples from non-obese smokers with a BMI < 30 kg/m2 and pack-years > 20.