TOP TEN perturbations for NM_000213 (Homo sapiens)

Organism: Homo sapiens
Gene: NM_000213
Selected probe(set): 204990_s_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of NM_000213 (204990_s_at) across 5339 perturbations tested by GENEVESTIGATOR:

brain tumor study 1 (medulloblastoma) / brain tumor study 1 (ependymoma)

Relative Expression (log2-ratio):-3.6809006
Number of Samples:22 / 46
Experimental brain tumor study 1 (medulloblastoma)
Primary tumor tissue sample from the brain of patients with medulloblastoma.
Control brain tumor study 1 (ependymoma)
Primary tumor tissue sample from the brain of patients with ependymoma.

TNF-?; TGF-?2 study 1 (intermediate) / untreated ARPE-19 cell sample

Relative Expression (log2-ratio):-3.5466986
Number of Samples:6 / 3
Experimental TNF-?; TGF-?2 study 1 (intermediate)
ARPE-19 retina pigment epithelial cell samples treated with TNF-? (10 ng/ml) and TGF-?2 (5 ng/ml). Samples were taken 16 and 24 hours after treatment.
Control untreated ARPE-19 cell sample
Untreated ARPE-19 retina pigment epithelial cell samples harvested before adding TNF-? (10 ng/ml) and TGF-?2 (5 ng/ml).

ovarian tumor study 11 (low grade) / normal ovarian surface epithelial cell sample

Relative Expression (log2-ratio):3.456606
Number of Samples:11 / 6
Experimental ovarian tumor study 11 (low grade)
Human microdissected tumor cells from the ovary of patients with low grade serous carcinoma.
Control normal ovarian surface epithelial cell sample
Human microdissected ovarian surface epithelial cell sample from the ovary of healthy individuals.

collecting duct carcinoma study 1 / normal kidney tissue

Relative Expression (log2-ratio):3.3483772
Number of Samples:2 / 2
Experimental collecting duct carcinoma study 1
Tumor tissue samples from the kidney of patients with collecting duct carcinoma (CDC).
Control normal kidney tissue
Normal fetal kidney tissue samples.

TNF-?; TGF-?2 study 1 (late) / untreated ARPE-19 cell sample

Relative Expression (log2-ratio):-3.272954
Number of Samples:6 / 3
Experimental TNF-?; TGF-?2 study 1 (late)
ARPE-19 retina pigment epithelial cell samples treated with TNF-? (10 ng/ml) and TGF-?2 (5 ng/ml). Samples were taken 42 and 60 hours after treatment.
Control untreated ARPE-19 cell sample
Untreated ARPE-19 retina pigment epithelial cell samples harvested before adding TNF-? (10 ng/ml) and TGF-?2 (5 ng/ml).

Merkel cell carcinoma study 3 (primary) / skin squamous cell carcinoma study 6

Relative Expression (log2-ratio):-3.2434502
Number of Samples:38 / 4
Experimental Merkel cell carcinoma study 3 (primary)
Primary tumor tissue from the skin of patients with Merkel cell carcinoma.
Control skin squamous cell carcinoma study 6
Primary tumor tissue from the skin of patients with squamous cell carcinoma (SCC).

ovarian tumor study 11 (borderline) / normal ovarian surface epithelial cell sample

Relative Expression (log2-ratio):2.9687777
Number of Samples:8 / 6
Experimental ovarian tumor study 11 (borderline)
Human microdissected tumor cells from the ovary of patients with low-malignant (borderline) tumors of the ovary.
Control normal ovarian surface epithelial cell sample
Human microdissected ovarian surface epithelial cell sample from the ovary of healthy individuals.

ovarian tumor study 15 / normal ovarian surface epithelial cell sample

Relative Expression (log2-ratio):2.9247704
Number of Samples:4 / 4
Experimental ovarian tumor study 15
Human pooled cancer samples from the ovary of patients with low-malignant (borderline) serous carcinoma of the ovary.
Control normal ovarian surface epithelial cell sample
Human epithelial cell samples from histopathological normal and non-cancerous ovary tissue from donors with non-cancerous, benign gynecological diseases.

brain tumor study 1 (pilocytic astrocytoma) / brain tumor study 1 (medulloblastoma)

Relative Expression (log2-ratio):2.8755121
Number of Samples:15 / 22
Experimental brain tumor study 1 (pilocytic astrocytoma)
Primary tumor tissue sample from the brain of patients with pilocytic astrocytoma.
Control brain tumor study 1 (medulloblastoma)
Primary tumor tissue sample from the brain of patients with medulloblastoma.

ovarian tumor study 14 / normal ovarian surface epithelial cell sample

Relative Expression (log2-ratio):2.771472
Number of Samples:4 / 4
Experimental ovarian tumor study 14
Human pooled cancer samples from the ovary of patients with moderate and poorly differentiated serous carcinoma of the ovary.
Control normal ovarian surface epithelial cell sample
Human epithelial cell samples from histopathological normal and non-cancerous ovary tissue from donors with non-cancerous, benign gynecological diseases.