TOP TEN perturbations for NM_000218 (Homo sapiens)

Organism: Homo sapiens
Gene: NM_000218
Selected probe(set): 204487_s_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of NM_000218 (204487_s_at) across 5339 perturbations tested by GENEVESTIGATOR:

adrenal gland cancer study 2 / normal adrenal cortex tissue

Relative Expression (log2-ratio):-2.8185368
Number of Samples:31 / 10
Experimental adrenal gland cancer study 2
Primary tumor tissue samples of the adrenal cortex from patients with adrenocortical carcinoma.
Control normal adrenal cortex tissue
Unaffected adrenal cortex tissue from control objects.

adrenal gland cancer study 4 / normal adrenal cortex tissue

Relative Expression (log2-ratio):-2.662365
Number of Samples:43 / 4
Experimental adrenal gland cancer study 4
Primary tumor tissue samples of the adrenal cortex from patients with adrenocortical carcinoma (ACC).
Control normal adrenal cortex tissue
Histological normal adrenal gland cortical tissue samples derived after autopsy.

adrenal gland cancer study 2 / adrenal gland cancer study 1

Relative Expression (log2-ratio):-2.6315527
Number of Samples:31 / 22
Experimental adrenal gland cancer study 2
Primary tumor tissue samples of the adrenal cortex from patients with adrenocortical carcinoma.
Control adrenal gland cancer study 1
Primary tumor tissue samples of the adrenal cortex from patients with adrenocortical adenoma.

adrenal gland cancer study 5 (ACC) / normal adrenal cortex tissue

Relative Expression (log2-ratio):-2.4343452
Number of Samples:34 / 4
Experimental adrenal gland cancer study 5 (ACC)
Primary tumor tissue samples of the adrenal cortex from patients with adrenocortical carcinoma (ACC).
Control normal adrenal cortex tissue
Histological normal adrenal gland cortical tissue samples.

ovarian tumor study 11 (borderline) / normal ovarian surface epithelial cell sample

Relative Expression (log2-ratio):2.3386745
Number of Samples:8 / 6
Experimental ovarian tumor study 11 (borderline)
Human microdissected tumor cells from the ovary of patients with low-malignant (borderline) tumors of the ovary.
Control normal ovarian surface epithelial cell sample
Human microdissected ovarian surface epithelial cell sample from the ovary of healthy individuals.

adrenal gland cancer study 5 (ACC) / adrenal gland cancer study 5 (ACA)

Relative Expression (log2-ratio):-2.334588
Number of Samples:34 / 58
Experimental adrenal gland cancer study 5 (ACC)
Primary tumor tissue samples of the adrenal cortex from patients with adrenocortical carcinoma (ACC).
Control adrenal gland cancer study 5 (ACA)
Primary tumor tissue samples of the adrenal cortex from patients with adrenocortical adenoma (ACA).

colorectal cancer study 43 (metastase; brain) / colorectal cancer study 43 (metastase; liver)

Relative Expression (log2-ratio):-2.3331575
Number of Samples:2 / 25
Experimental colorectal cancer study 43 (metastase; brain)
Metastatic tumor tissue obtained from the brain of patients with primary colorectal adenocarcinoma.
Control colorectal cancer study 43 (metastase; liver)
Metastatic tumor tissue obtained from the liver of patients with primary colon adenocarcinoma.

adrenal gland cancer study 5 (ACC) / AIMAH study 1

Relative Expression (log2-ratio):-2.0597343
Number of Samples:34 / 10
Experimental adrenal gland cancer study 5 (ACC)
Primary tumor tissue samples of the adrenal cortex from patients with adrenocortical carcinoma (ACC).
Control AIMAH study 1
Adrenal gland tissue samples from patients with ACTH-independant macronodular adrenal hyperplasia (AIMAH).

IL-4; GM-CSF study 1 (intermediate) / untreated monocyte sample

Relative Expression (log2-ratio):-2.0378551
Number of Samples:7 / 12
Experimental IL-4; GM-CSF study 1 (intermediate)
Monocytes, cultured with vehicle (DMSO/ethanol) and 500 U/ml IL-4 and 800 U/ml GM-CSF for 24 hours.
Control untreated monocyte sample
Freshly isolated human monocytes from healthy donors.

ovarian tumor study 28 (mucocarcinoid tumor) / ovarian tumor study 28 (carcinosarcoma)

Relative Expression (log2-ratio):2.0117168
Number of Samples:7 / 2
Experimental ovarian tumor study 28 (mucocarcinoid tumor)
Primary tumor tissue sample obtained from the ovary of female patients with malignant mucocarcinoid tumor.
Control ovarian tumor study 28 (carcinosarcoma)
Primary tumor tissue sample obtained from the ovary of female patients with carcinosarcoma.