TOP TEN perturbations for NM_000285 (Homo sapiens)

Organism: Homo sapiens
Gene: NM_000285
Selected probe(set): 202108_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of NM_000285 (202108_at) across 5392 perturbations tested by GENEVESTIGATOR:

conditioned medium study 1 (HS27a) / untreated monocyte (CD14+) sample

Relative Expression (log2-ratio):2.4851131
Number of Samples:2 / 2
Experimental conditioned medium study 1 (HS27a)
CD14+ monocytes treated with HS27a conditioned medium (CM) for 48h.
Control untreated monocyte (CD14+) sample
Untreated CD14+ monocytes from two different donors.

clear cell renal cell carcinoma study 4 (stage 1) / normal kidney tissue

Relative Expression (log2-ratio):-2.470502
Number of Samples:23 / 69
Experimental clear cell renal cell carcinoma study 4 (stage 1)
Primary tumor tissue from patients with stage 1 clear cell renal cell carcinoma (ccRCC).
Control normal kidney tissue
Normal kidney tissue samples obtained from healthy individuals.

clear cell renal cell carcinoma study 4 (stage 3) / normal kidney tissue

Relative Expression (log2-ratio):-2.3577566
Number of Samples:14 / 69
Experimental clear cell renal cell carcinoma study 4 (stage 3)
Primary tumor tissue from patients with stage 3 clear cell renal cell carcinoma (ccRCC).
Control normal kidney tissue
Normal kidney tissue samples obtained from healthy individuals.

clear cell renal cell carcinoma study 4 (stage 2) / normal kidney tissue

Relative Expression (log2-ratio):-2.3556614
Number of Samples:19 / 69
Experimental clear cell renal cell carcinoma study 4 (stage 2)
Primary tumor tissue from patients with stage 2 clear cell renal cell carcinoma (ccRCC).
Control normal kidney tissue
Normal kidney tissue samples obtained from healthy individuals.

nephroblastoma study 2 / normal kidney tissue

Relative Expression (log2-ratio):-2.338336
Number of Samples:4 / 3
Experimental nephroblastoma study 2
Tumor tissue samples from the kidney of patients with Wilms? tumor.
Control normal kidney tissue
Normal adult kidney tissue samples.

oncolytic herpes simplex virus study 2 / mock infected peripheral nerve sheath tumor (S462) cell sample

Relative Expression (log2-ratio):-2.3115778
Number of Samples:3 / 3
Experimental oncolytic herpes simplex virus study 2
Human malignant peripheral nerve sheath tumor (S462) cells infected with G207, an ICP34.5-deleted oncolytic herpes simplex virus (oHSV) for 6 hours.
Control mock infected peripheral nerve sheath tumor (S462) cell sample
Human malignant peripheral nerve sheath tumor (S462) cells mock infected for 6 hours.

collecting duct carcinoma study 1 / normal kidney tissue

Relative Expression (log2-ratio):-2.248846
Number of Samples:2 / 3
Experimental collecting duct carcinoma study 1
Tumor tissue samples from the kidney of patients with collecting duct carcinoma (CDC).
Control normal kidney tissue
Normal adult kidney tissue samples.

conditioned medium study 1 (HS5) / untreated monocyte (CD14+) sample

Relative Expression (log2-ratio):2.1433926
Number of Samples:2 / 2
Experimental conditioned medium study 1 (HS5)
CD14+ monocytes treated with HS5 conditioned medium (CM) for 48h.
Control untreated monocyte (CD14+) sample
Untreated CD14+ monocytes from two different donors.

clear cell renal cell carcinoma study 4 (stage 4) / normal kidney tissue

Relative Expression (log2-ratio):-2.1152287
Number of Samples:14 / 69
Experimental clear cell renal cell carcinoma study 4 (stage 4)
Primary tumor tissue from patients with stage 4 clear cell renal cell carcinoma (ccRCC).
Control normal kidney tissue
Normal kidney tissue samples obtained from healthy individuals.

clear cell renal cell carcinoma study 3 (non-obese; smoker) / smoking study 71 (non-obese)

Relative Expression (log2-ratio):-1.9563847
Number of Samples:16 / 15
Experimental clear cell renal cell carcinoma study 3 (non-obese; smoker)
Tumor tissue from patients with clear cell renal cell carcinoma (ccRCC). Patients were smokers and had a BMI < 30 kg/m2. Patients with late T4 stage and grade 4 tumors were excluded.
Control smoking study 71 (non-obese)
Kidney tissue samples from non-obese smokers with a BMI < 30 kg/m2 and pack-years > 20.