TOP TEN perturbations for NM_000339 (Homo sapiens)

Organism: Homo sapiens
Gene: NM_000339
Selected probe(set): 208354_s_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of NM_000339 (208354_s_at) across 5339 perturbations tested by GENEVESTIGATOR:

clear cell renal cell carcinoma study 3 (non-obese; smoker) / smoking study 71 (non-obese)

Relative Expression (log2-ratio):-3.5305767
Number of Samples:16 / 15
Experimental clear cell renal cell carcinoma study 3 (non-obese; smoker)
Tumor tissue from patients with clear cell renal cell carcinoma (ccRCC). Patients were smokers and had a BMI < 30 kg/m2. Patients with late T4 stage and grade 4 tumors were excluded.
Control smoking study 71 (non-obese)
Kidney tissue samples from non-obese smokers with a BMI < 30 kg/m2 and pack-years > 20.

clear cell renal cell carcinoma study 4 (stage 3) / normal kidney tissue

Relative Expression (log2-ratio):-3.4527903
Number of Samples:14 / 69
Experimental clear cell renal cell carcinoma study 4 (stage 3)
Primary tumor tissue from patients with stage 3 clear cell renal cell carcinoma (ccRCC).
Control normal kidney tissue
Normal kidney tissue samples obtained from healthy individuals.

clear cell renal cell carcinoma study 4 (stage 2) / normal kidney tissue

Relative Expression (log2-ratio):-3.3698921
Number of Samples:19 / 69
Experimental clear cell renal cell carcinoma study 4 (stage 2)
Primary tumor tissue from patients with stage 2 clear cell renal cell carcinoma (ccRCC).
Control normal kidney tissue
Normal kidney tissue samples obtained from healthy individuals.

clear cell renal cell carcinoma study 4 (stage 4) / normal kidney tissue

Relative Expression (log2-ratio):-3.1808662
Number of Samples:14 / 69
Experimental clear cell renal cell carcinoma study 4 (stage 4)
Primary tumor tissue from patients with stage 4 clear cell renal cell carcinoma (ccRCC).
Control normal kidney tissue
Normal kidney tissue samples obtained from healthy individuals.

clear cell renal cell carcinoma study 3 (non-obese; smoker) / normal kidney tissue

Relative Expression (log2-ratio):-3.127036
Number of Samples:16 / 25
Experimental clear cell renal cell carcinoma study 3 (non-obese; smoker)
Tumor tissue from patients with clear cell renal cell carcinoma (ccRCC). Patients were smokers and had a BMI < 30 kg/m2. Patients with late T4 stage and grade 4 tumors were excluded.
Control normal kidney tissue
Normal kidney tissue samples obtained from healthy, non-smoking and non-obese individuals.

clear cell renal cell carcinoma study 4 (stage 1) / normal kidney tissue

Relative Expression (log2-ratio):-3.0825863
Number of Samples:23 / 69
Experimental clear cell renal cell carcinoma study 4 (stage 1)
Primary tumor tissue from patients with stage 1 clear cell renal cell carcinoma (ccRCC).
Control normal kidney tissue
Normal kidney tissue samples obtained from healthy individuals.

clear cell renal cell carcinoma study 3 (non-obese; non-smoker) / normal kidney tissue

Relative Expression (log2-ratio):-2.8309402
Number of Samples:25 / 25
Experimental clear cell renal cell carcinoma study 3 (non-obese; non-smoker)
Tumor tissue from patients with clear cell renal cell carcinoma (ccRCC). Patients were non-smokers and had a BMI < 30 kg/m2. Patients with late T4 stage and grade 4 tumors were excluded.
Control normal kidney tissue
Normal kidney tissue samples obtained from healthy, non-smoking and non-obese individuals.

collecting duct carcinoma study 1 / normal kidney tissue

Relative Expression (log2-ratio):-2.7677774
Number of Samples:2 / 3
Experimental collecting duct carcinoma study 1
Tumor tissue samples from the kidney of patients with collecting duct carcinoma (CDC).
Control normal kidney tissue
Normal adult kidney tissue samples.

nephroblastoma study 2 / normal kidney tissue

Relative Expression (log2-ratio):-2.7562094
Number of Samples:4 / 3
Experimental nephroblastoma study 2
Tumor tissue samples from the kidney of patients with Wilms? tumor.
Control normal kidney tissue
Normal adult kidney tissue samples.

renal cell carcinoma study 5 (papillary type) / normal kidney tissue

Relative Expression (log2-ratio):-2.7233267
Number of Samples:19 / 3
Experimental renal cell carcinoma study 5 (papillary type)
Tumor tissue samples from the kidney of patients with papillary renal cell carcinoma (pRCC).
Control normal kidney tissue
Normal adult kidney tissue samples.