TOP TEN perturbations for NM_000349 (Homo sapiens)

Organism: Homo sapiens
Gene: NM_000349
Selected probe(set): 204548_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of NM_000349 (204548_at) across 5339 perturbations tested by GENEVESTIGATOR:

endometriosis study 2 / normal endometrium tissue

Relative Expression (log2-ratio):5.7033663
Number of Samples:10 / 10
Experimental endometriosis study 2
Endometrium tissue from patients with endometriosis.
Control normal endometrium tissue
Normal endometrium tissue.

endometriosis study 1 / normal endometrium tissue

Relative Expression (log2-ratio):5.119796
Number of Samples:18 / 23
Experimental endometriosis study 1
Endometrium and ovary tissue from patients with endometriosis.
Control normal endometrium tissue
Normal endometrium tissue.

ovarian tumor study 28 (mucocarcinoid tumor) / ovarian tumor study 28 (carcinosarcoma)

Relative Expression (log2-ratio):4.3464804
Number of Samples:7 / 2
Experimental ovarian tumor study 28 (mucocarcinoid tumor)
Primary tumor tissue sample obtained from the ovary of female patients with malignant mucocarcinoid tumor.
Control ovarian tumor study 28 (carcinosarcoma)
Primary tumor tissue sample obtained from the ovary of female patients with carcinosarcoma.

LPS study 4 (shRNA contr.) / mock treated / transduced MONO-MAC-6 cell sample

Relative Expression (log2-ratio):-4.34521
Number of Samples:2 / 2
Experimental LPS study 4 (shRNA contr.)
MONO-MAC-6 (MM6) cells were transduced with a control shRNA and then treated with 10 ng/ml lipopolysaccharide (LPS). ATC code:---
Control mock treated / transduced MONO-MAC-6 cell sample
MONO-MAC-6 (MM6) cells were transduced with a control shRNA and then mock treated.

ovarian tumor study 14 / normal ovarian surface epithelial cell sample

Relative Expression (log2-ratio):-4.298645
Number of Samples:4 / 4
Experimental ovarian tumor study 14
Human pooled cancer samples from the ovary of patients with moderate and poorly differentiated serous carcinoma of the ovary.
Control normal ovarian surface epithelial cell sample
Human epithelial cell samples from histopathological normal and non-cancerous ovary tissue from donors with non-cancerous, benign gynecological diseases.

LPS study 4 (shRNA cycT1) / cycT1 depletion study 2 (shRNA)

Relative Expression (log2-ratio):-4.096842
Number of Samples:2 / 2
Experimental LPS study 4 (shRNA cycT1)
MONO-MAC-6 (MM6) cells were transduced with shRNA against cyclin T1 and then treated with 10 ng/ml lipopolysaccharide (LPS). ATC code:---
Control cycT1 depletion study 2 (shRNA)
MONO-MAC-6 (MM6) cells were transduced with shRNA against cyclin T1 and then mock treated.

embryonic development study 1 (9wk) / embryonic development study 1 (4wk)

Relative Expression (log2-ratio):3.87572
Number of Samples:3 / 3
Experimental embryonic development study 1 (9wk)
Human embryos at 9th week after fertilization. Embryos were obtained after therapeutic termination of pregnancy with mifepristone.
Control embryonic development study 1 (4wk)
Human embryos at 4th week after fertilization. Embryos were obtained after therapeutic termination of pregnancy with mifepristone.

AML study 1 (t(15;17)(q22;q11-12)) / normal bone marrow sample

Relative Expression (log2-ratio):3.8748827
Number of Samples:36 / 74
Experimental AML study 1 (t(15;17)(q22;q11-12))
Bone marrow samples of patients with acute promyelocytic leukemia [subtype of acute myeloid leukemia (AML)] with genetic aberration (t(15;17)(q22;q11-12)/PML-RAR? and variations).
Control normal bone marrow sample
Non-leukemic and healthy bone marrow sample.

LPS study 4 / mock treated MONO-MAC-6 cell sample

Relative Expression (log2-ratio):-3.746398
Number of Samples:2 / 2
Experimental LPS study 4
MONO-MAC-6 (MM6) cells were treated with 10 ng/ml lipopolysaccharide (LPS). ATC code:---
Control mock treated MONO-MAC-6 cell sample
MONO-MAC-6 (MM6) cells mock treated.

ovarian tumor study 27 (papillary serous cystadenocarcinoma; metastase) / ovarian tumor study 27 (papillary serous cystadenocarcinoma; bmp; primary)

Relative Expression (log2-ratio):-3.5629082
Number of Samples:53 / 18
Experimental ovarian tumor study 27 (papillary serous cystadenocarcinoma; metastase)
Metastatic tumor tissue samples obtained from different anatomical sites (colon, omentum, peritoneum and unstated sites) of female patients with primary papillary serous cystadenocarcinoma of the ovary.
Control ovarian tumor study 27 (papillary serous cystadenocarcinoma; bmp; primary)
Primary tumor tissue samples obtained from the ovary of female patients with papillary serous cystadenocarcinoma with borderline malignant potential (bmp).