TOP TEN perturbations for NM_000355 (Homo sapiens)

Organism: Homo sapiens
Gene: NM_000355
Selected probe(set): 204043_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of NM_000355 (204043_at) across 5339 perturbations tested by GENEVESTIGATOR:

Dengue hemorrhagic fever study 1 (2d) / Dengue hemorrhagic fever study 1 (convalescent)

Relative Expression (log2-ratio):2.8140554
Number of Samples:3 / 12
Experimental Dengue hemorrhagic fever study 1 (2d)
Peripheral blood mononuclear cell (PBMC) samples derived from the blood of Venezuelan individuals 2 days after the onset of Dengue hemorrhagic fever.
Control Dengue hemorrhagic fever study 1 (convalescent)
Peripheral blood mononuclear cell (PBMC) samples derived from the blood of Venezuelan individuals 28 days after the onset of Dengue hemorrhagic fever.

Dengue fever study 1 (early) / Dengue fever study 1 (convalescent)

Relative Expression (log2-ratio):2.5119028
Number of Samples:2 / 11
Experimental Dengue fever study 1 (early)
Peripheral blood mononuclear cell (PBMC) samples derived from the blood of Venezuelan individuals one day after the onset of Dengue fever.
Control Dengue fever study 1 (convalescent)
Peripheral blood mononuclear cell (PBMC) samples derived from the blood of Venezuelan individuals 28 days after the onset of Dengue fever.

OPM-1 / MM1.S

Relative Expression (log2-ratio):-2.2978096
Number of Samples:4 / 4
Experimental OPM-1
Human primary cancer cell line derived from the peripheral blood of a patient with multiple myeloma. Dexamethasone-resistant. Synonyms:OPM1 Cellosaurus code:
Control MM1.S
Human primary cancer cell line derived from the peripheral blood of a patient with multiple myeloma. Dexamethasone-sensitive. Parental cell line:: MM.1 Synonyms:MM.1S; MM1-S; MM-1S; MM1S Cellosaurus code:

pediatric meningococcal sepsis study 3 (late) / normal PBMC (CD14+) sample

Relative Expression (log2-ratio):2.15654
Number of Samples:3 / 3
Experimental pediatric meningococcal sepsis study 3 (late)
CD14 positive cell fraction (PBMC CD 14+) isolated from peripheral blood mononuclear cells. Peripheral blood mononuclear cells were derived from whole blood drawn from children with meningococcal sepsis 24 hours after admission to the pediatric intensive care unit.
Control normal PBMC (CD14+) sample
CD14 positive cell fraction (PBMC CD 14+) isolated from peripheral blood mononuclear cells. Peripheral blood mononuclear cells were derived from whole blood drawn from matched control subjects.

cutaneous sarcoidosis study 1 (lesional) / normal skin tissue

Relative Expression (log2-ratio):2.1536179
Number of Samples:13 / 5
Experimental cutaneous sarcoidosis study 1 (lesional)
Lesional skin biopsies from patients with acute cutaneous sarcoidosis.
Control normal skin tissue
Skin biopsy samples from healthy control subjects.

pediatric meningococcal sepsis study 3 (intermediate) / normal PBMC (CD14+) sample

Relative Expression (log2-ratio):2.1137066
Number of Samples:3 / 3
Experimental pediatric meningococcal sepsis study 3 (intermediate)
CD14 positive cell fraction (PBMC CD 14+) isolated from peripheral blood mononuclear cells. Peripheral blood mononuclear cells were derived from whole blood drawn from children with meningococcal sepsis 8 hours after admission to the pediatric intensive care unit.
Control normal PBMC (CD14+) sample
CD14 positive cell fraction (PBMC CD 14+) isolated from peripheral blood mononuclear cells. Peripheral blood mononuclear cells were derived from whole blood drawn from matched control subjects.

breast cancer study 40 (metastase; ovary) / ovarian tumor study 28 (clear cell adenocarcinoma)

Relative Expression (log2-ratio):-2.094101
Number of Samples:44 / 6
Experimental breast cancer study 40 (metastase; ovary)
Metastatic tumor tissue obtained from the ovary of female patients with primary breast cancer.
Control ovarian tumor study 28 (clear cell adenocarcinoma)
Primary tumor tissue sample obtained from the ovary of female patients with clear cell adenocarcinoma.

systemic lupus erythematosus study 6 / normal monocyte sample (CD16+)

Relative Expression (log2-ratio):2.0744343
Number of Samples:4 / 3
Experimental systemic lupus erythematosus study 6
FACS-sorted CD16-positive resident monocytes (CD15-negative/CD14-positive/CD16-positive) derived from peripheral blood mononuclear cells (PBMC?s) from patients with systemic lupus erythematosus (SLE).
Control normal monocyte sample (CD16+)
FACS-sorted CD16-positive resident monocytes (CD15-negative/CD14-positive/CD16-positive) derived from peripheral blood mononuclear cells (PBMC?s) from healthy individuals.

cutaneous sarcoidosis study 1 (lesional) / cutaneous sarcoidosis study 1 (non-lesional)

Relative Expression (log2-ratio):2.030367
Number of Samples:13 / 9
Experimental cutaneous sarcoidosis study 1 (lesional)
Lesional skin biopsies from patients with acute cutaneous sarcoidosis.
Control cutaneous sarcoidosis study 1 (non-lesional)
Non-lesional skin biopsies from patients with acute cutaneous sarcoidosis.

ovarian tumor study 28 (carcinosarcoma) / ovarian tumor study 28 (clear cell adenocarcinoma)

Relative Expression (log2-ratio):-1.9515171
Number of Samples:2 / 6
Experimental ovarian tumor study 28 (carcinosarcoma)
Primary tumor tissue sample obtained from the ovary of female patients with carcinosarcoma.
Control ovarian tumor study 28 (clear cell adenocarcinoma)
Primary tumor tissue sample obtained from the ovary of female patients with clear cell adenocarcinoma.