TOP TEN perturbations for NM_000366 (Homo sapiens)

Organism: Homo sapiens
Gene: NM_000366
Selected probe(set): 206116_s_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of NM_000366 (206116_s_at) across 5392 perturbations tested by GENEVESTIGATOR:

basal cell carcinoma study 3 / normal epidermal keratinocytes

Relative Expression (log2-ratio):4.446213
Number of Samples:4 / 2
Experimental basal cell carcinoma study 3
Primary tumor tissue from the eyelid of patients with basal cell carcinoma (BCC).
Control normal epidermal keratinocytes
Normal human epidermal keratinocytes (NHEK) (Kurabo Ind., Ltd., Osaka, Japan) cultured in HuMedia-KB2 medium at 37?C in humidified air containing 5% CO2.

prostate cancer study 1 (meta.) / benign prostate tissue

Relative Expression (log2-ratio):-3.6793194
Number of Samples:6 / 6
Experimental prostate cancer study 1 (meta.)
Metastatic prostate cancer samples.
Control benign prostate tissue
Benign prostate samples.

bladder cancer study 1 / normal bladder tissue

Relative Expression (log2-ratio):-3.4993105
Number of Samples:3 / 3
Experimental bladder cancer study 1
Low grade superficial tumor samples.
Control normal bladder tissue
Normal bladder tissue.

Barrett's esophagus study 3 / normal esophageal epithelium sample

Relative Expression (log2-ratio):3.423688
Number of Samples:17 / 18
Experimental Barrett's esophagus study 3
Esophageal epithelium samples from areas with Barrett's esophagus metaplasia which were recovered by laser capture microdissection.
Control normal esophageal epithelium sample
Histologically normal esophageal squamous cell epithelium biopsy samples from patients that were investigated for esophageal pain, but diagnosed as healthy.

TGF-? study 5 (late) / untreated A549 cell sample

Relative Expression (log2-ratio):3.3871899
Number of Samples:3 / 3
Experimental TGF-? study 5 (late)
Human A549 cells were treated with 5ng/ml porcine TGF-? after serum-starving for 24h. Samples were taken 72 hours after TGF-? treatment.
Control untreated A549 cell sample
A549 cells were grown for 24 hours. Samples were taken immediately before TGF-? treatment.

hepatocyte (ESC) / Hep-G2

Relative Expression (log2-ratio):3.1180449
Number of Samples:8 / 9
Experimental hepatocyte (ESC)
Hepatocyte-like cells differentiated from embryonic stem cells (ESC)
Control Hep-G2
Human primary cancer cell line derived from the liver of a patient with hepatocellular carcinoma. Synonyms:HEP-G2; Hep G2; HEP G2; HepG2; HEPG2 Cellosaurus code:

prostate cancer study 1 (meta.) / prostate cancer study 1 (prim.)

Relative Expression (log2-ratio):-3.017849
Number of Samples:6 / 7
Experimental prostate cancer study 1 (meta.)
Metastatic prostate cancer samples.
Control prostate cancer study 1 (prim.)
Primary prostate cancer samples.

CD44s overexpr. study 1 / normal HEK-293 cell sample

Relative Expression (log2-ratio):2.9985228
Number of Samples:3 / 3
Experimental CD44s overexpr. study 1
Human embryonic kidney cell line HEK-293 transfected with pcDNA3.1(-) vector containing codon-optimized human CD44 sequence for expression.
Control normal HEK-293 cell sample
Untransfected, native human embryonic kidney cell line HEK-293 cell samples.

bladder cancer study 2 / normal bladder tissue

Relative Expression (log2-ratio):-2.9742708
Number of Samples:3 / 3
Experimental bladder cancer study 2
High grade superficial tumors with an unclear clinical behavior.
Control normal bladder tissue
Normal bladder tissue.

TGF-? study 5 (intermediate) / untreated A549 cell sample

Relative Expression (log2-ratio):2.951519
Number of Samples:9 / 3
Experimental TGF-? study 5 (intermediate)
Human A549 cells were treated with 5ng/ml porcine TGF-? after serum-starving for 24h. Samples were taken 8, 16, 24 hours after TGF-? treatment.
Control untreated A549 cell sample
A549 cells were grown for 24 hours. Samples were taken immediately before TGF-? treatment.