TOP TEN perturbations for NM_000424 (Homo sapiens)

Organism: Homo sapiens
Gene: NM_000424
Selected probe(set): 201820_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of NM_000424 (201820_at) across 5392 perturbations tested by GENEVESTIGATOR:

AsPC-1 / BxPC-3

Relative Expression (log2-ratio):-7.0533066
Number of Samples:3 / 3
Experimental AsPC-1
Human xenograft derived metastatic cancer cell line derived from mouse xenografts initiated with metastatic cells from the ascites derived from a 62 years old female Caucasian patient with pancreatic adenocarcinoma. Synonyms:AsPc-1; Aspc-1; ASPC-1; As-PC1; ASPC1; AsPC1; Aspc1; AsPc1 Cellosaurus code:
Control BxPC-3
Human pancreatic adenocarcinoma cell line derived from a 61 years old female patient. Synonyms:BxPc-3; BXPC-3; Bx-PC3; BXPC3; BxPC3; BxPc3 Cellosaurus code:

esophageal adenocarcinoma study 1 / normal esophageal epithelium sample

Relative Expression (log2-ratio):-7.0240526
Number of Samples:20 / 18
Experimental esophageal adenocarcinoma study 1
Esophageal adenocarcinoma (EAC) samples of affected epithelium recovered by laser capture microdissection technique.
Control normal esophageal epithelium sample
Histologically normal esophageal squamous cell epithelium biopsy samples from patients that were investigated for esophageal pain, but diagnosed as healthy.

non-small cell lung cancer study 8 (squamous cell carcinoma) / adjacent lung tissue

Relative Expression (log2-ratio):6.996376
Number of Samples:27 / 65
Experimental non-small cell lung cancer study 8 (squamous cell carcinoma)
Primary tumor tissue sample obtained from the lung of patients squamous cell carcinoma.
Control adjacent lung tissue
Histological normal lung tissue samples from patients with lung cancer.

lung squamous cell carcinoma study 1 / normal lung tissue

Relative Expression (log2-ratio):6.952853
Number of Samples:31 / 44
Experimental lung squamous cell carcinoma study 1
Primary lung squamous cell carcinoma samples of a patient with non-small cell lung cancer.
Control normal lung tissue
Histologically normal lung tissue.

non-small cell lung cancer study 8 (squamous cell carcinoma) / non-small cell lung cancer study 8 (large cell carcinoma)

Relative Expression (log2-ratio):6.8444796
Number of Samples:27 / 18
Experimental non-small cell lung cancer study 8 (squamous cell carcinoma)
Primary tumor tissue sample obtained from the lung of patients squamous cell carcinoma.
Control non-small cell lung cancer study 8 (large cell carcinoma)
Primary tumor tissue sample obtained from the lung of patients large cell carcinoma.

non-small cell lung cancer study 8 (squamous cell carcinoma) / non-small cell lung cancer study 8 (adenocarcinoma)

Relative Expression (log2-ratio):6.60709
Number of Samples:27 / 45
Experimental non-small cell lung cancer study 8 (squamous cell carcinoma)
Primary tumor tissue sample obtained from the lung of patients squamous cell carcinoma.
Control non-small cell lung cancer study 8 (adenocarcinoma)
Primary tumor tissue sample obtained from the lung of patients adenocarcinoma.

esophageal squamous cell carcinoma study 1 / esophageal adenocarcinoma study 1

Relative Expression (log2-ratio):6.537816
Number of Samples:8 / 20
Experimental esophageal squamous cell carcinoma study 1
Esophageal squamous cell carcinoma (ESCC) biopsy samples from chemotherapy-naive patients with histological grading G1 (well differentiated) and UICC stage II and III, which undergone esophagectomy.
Control esophageal adenocarcinoma study 1
Esophageal adenocarcinoma (EAC) samples of affected epithelium recovered by laser capture microdissection technique.

SW620 / SW480

Relative Expression (log2-ratio):-6.026885
Number of Samples:62 / 63
Experimental SW620
Human metastatic cancer cell line derived from the lymph node of a patient with adenocarcinoma of the colon. Synonyms:SW-620; SW 620; SW.620 Cellosaurus code:
Control SW480
Human primary cancer cell line derived from the colon of a male patient with adenocarcinoma. Synonyms:SW-480; SW 480; SW480E Cellosaurus code:

Barrett's esophagus study 3 / normal esophageal epithelium sample

Relative Expression (log2-ratio):-5.710372
Number of Samples:17 / 18
Experimental Barrett's esophagus study 3
Esophageal epithelium samples from areas with Barrett's esophagus metaplasia which were recovered by laser capture microdissection.
Control normal esophageal epithelium sample
Histologically normal esophageal squamous cell epithelium biopsy samples from patients that were investigated for esophageal pain, but diagnosed as healthy.

Merkel cell carcinoma study 3 (metastatic) / normal skin tissue

Relative Expression (log2-ratio):-5.523589
Number of Samples:22 / 64
Experimental Merkel cell carcinoma study 3 (metastatic)
Metastatic tumor tissue from different metastatic sites (skin, lymph node, parotid gland) of patients with Merkel cell carcinoma of the skin.
Control normal skin tissue
Normal skin samples from healthy donors.