TOP TEN perturbations for NP_689643 (Homo sapiens)

Organism: Homo sapiens
Gene: NP_689643
Selected probe(set): 229768_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of NP_689643 (229768_at) across 6593 perturbations tested by GENEVESTIGATOR:

ALDH1A1/ALDH3A1 depletion study 1 (siRNA) / control transfected A-549 cell sample

Relative Expression (log2-ratio):6.4340487
Number of Samples:4 / 4
Experimental ALDH1A1/ALDH3A1 depletion study 1 (siRNA)
Human primary cancer cell line A-549 stably transduced with lentiviral vectors containing specific siRNA sequences against ALDH1A1 (Aldehyde dehydrogenase 1 family, member A1) and ALDH3A1 (Aldehyde dehydrogenase 3 family, member A1) (Lenti 1+3 cells).
Control control transfected A-549 cell sample
Human primary cancer cell line A-549 stably transduced with lentiviral vector containing siRNA against GFP. 4 clones of control cell line were prepared (clone GFP1-4).

influenza virus study 10 (A/H5N2) / influenza virus study 4 (A/H1N1)

Relative Expression (log2-ratio):5.025445
Number of Samples:3 / 3
Experimental influenza virus study 10 (A/H5N2)
Human carcinoma cell line A549 infected with influenza A virus subtype influenza virus A/duck/Malaysia/F189/07/2004(H5N2). Samples were taken 10 hours post-infection.
Control influenza virus study 4 (A/H1N1)
Human carcinoma cell line A549 infected with influenza A virus subtype A/WSN/33 (H1N1). Samples were taken 10 hours post-infection.

influenza virus study 10 (A/H5N2) / influenza virus study 9 (A/pH1N1)

Relative Expression (log2-ratio):4.889159
Number of Samples:3 / 3
Experimental influenza virus study 10 (A/H5N2)
Human carcinoma cell line A549 infected with influenza A virus subtype influenza virus A/duck/Malaysia/F189/07/2004(H5N2). Samples were taken 10 hours post-infection.
Control influenza virus study 9 (A/pH1N1)
Human carcinoma cell line A549 infected with influenza A virus subtype [A/Singapore/478/2009 (pH1N1)]. Samples were taken 10 hours post-infection.

influenza virus study 11 (A/H5N3) / influenza virus study 4 (A/H1N1)

Relative Expression (log2-ratio):4.4355326
Number of Samples:3 / 3
Experimental influenza virus study 11 (A/H5N3)
Human carcinoma cell line A549 infected with influenza A virus subtype influenza virus A/duck/Malaysia/F119/3/1997(H5N3). Samples were taken 10 hours post-infection.
Control influenza virus study 4 (A/H1N1)
Human carcinoma cell line A549 infected with influenza A virus subtype A/WSN/33 (H1N1). Samples were taken 10 hours post-infection.

influenza virus study 11 (A/H5N3) / influenza virus study 9 (A/pH1N1)

Relative Expression (log2-ratio):4.299247
Number of Samples:3 / 3
Experimental influenza virus study 11 (A/H5N3)
Human carcinoma cell line A549 infected with influenza A virus subtype influenza virus A/duck/Malaysia/F119/3/1997(H5N3). Samples were taken 10 hours post-infection.
Control influenza virus study 9 (A/pH1N1)
Human carcinoma cell line A549 infected with influenza A virus subtype [A/Singapore/478/2009 (pH1N1)]. Samples were taken 10 hours post-infection.

TGF-ß study 5 (late) / untreated A549 cell sample

Relative Expression (log2-ratio):-4.1020412
Number of Samples:3 / 3
Experimental TGF-ß study 5 (late)
Human A549 cells were treated with 5ng/ml porcine TGF-ß after serum-starving for 24h. Samples were taken 72 hours after TGF-ß treatment.
Control untreated A549 cell sample
A549 cells were grown for 24 hours. Samples were taken immediately before TGF-ß treatment.

prostate cancer study 1 (prim.) / benign prostate tissue

Relative Expression (log2-ratio):3.7316847
Number of Samples:7 / 6
Experimental prostate cancer study 1 (prim.)
Primary prostate cancer samples.
Control benign prostate tissue
Benign prostate samples.

influenza virus study 7 (A/pH1N1) / influenza virus study 3 (A/H1N1)

Relative Expression (log2-ratio):-3.684475
Number of Samples:3 / 4
Experimental influenza virus study 7 (A/pH1N1)
Human carcinoma cell line A549 infected with influenza A virus subtype [A/Singapore/478/2009 (pH1N1)]. Samples were taken 6 hours post-infection.
Control influenza virus study 3 (A/H1N1)
Human carcinoma cell line A549 infected with influenza A virus subtype A/WSN/33 (H1N1). Samples were taken 6 hours post-infection.

influenza virus study 5 (A/pH1N1) / influenza virus study 1 (A/H1N1)

Relative Expression (log2-ratio):-3.581664
Number of Samples:3 / 3
Experimental influenza virus study 5 (A/pH1N1)
Human carcinoma cell line A549 infected with influenza A virus subtype [A/Singapore/478/2009 (pH1N1)]. Samples were taken 2 hours post-infection.
Control influenza virus study 1 (A/H1N1)
Human carcinoma cell line A549 infected with influenza A virus subtype A/WSN/33 (H1N1). Samples were taken 2 hours post-infection.

influenza virus study 6 (A/pH1N1) / influenza virus study 2 (A/H1N1)

Relative Expression (log2-ratio):-3.3623943
Number of Samples:3 / 2
Experimental influenza virus study 6 (A/pH1N1)
Human carcinoma cell line A549 infected with influenza A virus subtype [A/Singapore/478/2009 (pH1N1)]. Samples were taken 4 hours post-infection.
Control influenza virus study 2 (A/H1N1)
Human carcinoma cell line A549 infected with influenza A virus subtype A/WSN/33 (H1N1). Samples were taken 4 hours post-infection.