TOP TEN perturbations for A6BM72 (Homo sapiens)

Organism: Homo sapiens
Gene: A6BM72
Selected probe(set): 1552439_s_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of A6BM72 (1552439_s_at) across 5638 perturbations tested by GENEVESTIGATOR:

brain tumor study 1 (pilocytic astrocytoma) / brain tumor study 1 (medulloblastoma)

Relative Expression (log2-ratio):4.2268963
Number of Samples:15 / 22
Experimental brain tumor study 1 (pilocytic astrocytoma)
Primary tumor tissue sample from the brain of patients with pilocytic astrocytoma.
Control brain tumor study 1 (medulloblastoma)
Primary tumor tissue sample from the brain of patients with medulloblastoma.

brain tumor study 1 (pilocytic astrocytoma) / brain tumor study 1 (ependymoma)

Relative Expression (log2-ratio):3.40736
Number of Samples:15 / 46
Experimental brain tumor study 1 (pilocytic astrocytoma)
Primary tumor tissue sample from the brain of patients with pilocytic astrocytoma.
Control brain tumor study 1 (ependymoma)
Primary tumor tissue sample from the brain of patients with ependymoma.

brain tumor study 1 (pilocytic astrocytoma) / normal brain tissue

Relative Expression (log2-ratio):3.334261
Number of Samples:15 / 12
Experimental brain tumor study 1 (pilocytic astrocytoma)
Primary tumor tissue sample from the brain of patients with pilocytic astrocytoma.
Control normal brain tissue
Histologically normal and non-neoplastic tissue sample from different brain anatomical sites of patients with primary brain tumors.

rapidly progressive glomerulonephritis; ANCA-associated vasculitis study 5 (tubulointerstitium) / tumor adjacent tubulointerstitium tissue

Relative Expression (log2-ratio):3.129263
Number of Samples:21 / 3
Experimental rapidly progressive glomerulonephritis; ANCA-associated vasculitis study 5 (tubulointerstitium)
Tubulointerstitium tissue sample obtained by microdissection from kidney biopsy, from patients suffering from rapidly progressive glomerulonephritis and antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. Donors were positive for ANCA-antibody. Biopsy samples were obtained from the European Renal cDNA Bank-Kroener-Fresenius biopsy bank. All biopsies were stratified by a reference pathologist.
Control tumor adjacent tubulointerstitium tissue
Normal tubulointerstitium tissue adjacent to tumor. Samples were obtained during tumor nephrectomy. Biopsy samples were obtained from the European Renal cDNA Bank-Kroener-Fresenius biopsy bank. All biopsies were stratified by a reference pathologist.

brain tumor study 1 (pilocytic astrocytoma) / brain tumor study 1 (glioblastoma)

Relative Expression (log2-ratio):3.0855017
Number of Samples:15 / 34
Experimental brain tumor study 1 (pilocytic astrocytoma)
Primary tumor tissue sample from the brain of patients with pilocytic astrocytoma.
Control brain tumor study 1 (glioblastoma)
Primary tumor tissue sample from the brain of patients with glioblastoma multiformae.

rapidly progressive glomerulonephritis; ANCA-associated vasculitis study 2 / tumor adjacent tubulointerstitium tissue

Relative Expression (log2-ratio):2.9964442
Number of Samples:21 / 3
Experimental rapidly progressive glomerulonephritis; ANCA-associated vasculitis study 2
Tubulointerstitium tissue sample obtained by microdissection from kidney biopsy, from patients suffering from rapidly progressive glomerulonephritis and antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. Donors were positive for ANCA-antibody. Biopsy samples were obtained from the European Renal cDNA Bank-Kroener-Fresenius biopsy bank. All biopsies were stratified by a reference pathologist..
Control tumor adjacent tubulointerstitium tissue
Normal renal tubulointerstitium tissue adjacent to tumor. Samples were obtained from tumor nephrectomies.

colorectal cancer study 43 (metastase; brain) / colorectal cancer study 43 (metastase; liver)

Relative Expression (log2-ratio):2.9823103
Number of Samples:2 / 25
Experimental colorectal cancer study 43 (metastase; brain)
Metastatic tumor tissue obtained from the brain of patients with primary colorectal adenocarcinoma.
Control colorectal cancer study 43 (metastase; liver)
Metastatic tumor tissue obtained from the liver of patients with primary colon adenocarcinoma.

glioma study 17 (oligodendroglioma; unsorted) / non-tumor cortical tissue

Relative Expression (log2-ratio):2.9727554
Number of Samples:3 / 4
Experimental glioma study 17 (oligodendroglioma; unsorted)
Brain cells isolated from low grade oligodendroglioma (grade II). Tumor tissue was dissociated using enzymatic treatment and all cells were used for RNA isolation. Patients were 39 ± 9 years old.
Control non-tumor cortical tissue
Cortical tissue obtained from patients with epilepsy, but without any manifested brain cancer. The tissue was dissociated using enzymatic treatment, but all brain cell types were used for analyses.

glioma study 16 (oligodendroglioma) / normal brain tissue

Relative Expression (log2-ratio):2.8951292
Number of Samples:7 / 2
Experimental glioma study 16 (oligodendroglioma)
Primary oligodendroglioma tissues obtained from the operating room. Tumors were diagnosed and graded according to the current WHO classification (grade OGII-III).
Control normal brain tissue
Normal brain tissue sample from healthy donors.

rapidly progressive glomerulonephritis; ANCA-associated vasculitis study 5 (tubulointerstitium) / minimal change disease study 8 (tubulointerstitium)

Relative Expression (log2-ratio):2.8945656
Number of Samples:21 / 5
Experimental rapidly progressive glomerulonephritis; ANCA-associated vasculitis study 5 (tubulointerstitium)
Tubulointerstitium tissue sample obtained by microdissection from kidney biopsy, from patients suffering from rapidly progressive glomerulonephritis and antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. Donors were positive for ANCA-antibody. Biopsy samples were obtained from the European Renal cDNA Bank-Kroener-Fresenius biopsy bank. All biopsies were stratified by a reference pathologist.
Control minimal change disease study 8 (tubulointerstitium)
Tubulointerstitium tissue sample obtained by microdissection from kidney biopsy, from patients suffering from minimal change disease. Biopsy samples were obtained from the European Renal cDNA Bank-Kroener-Fresenius biopsy bank. All biopsies were stratified by a reference pathologist.