TOP TEN perturbations for O15061 (Homo sapiens)

Organism: Homo sapiens
Gene: O15061
Selected probe(set): 212730_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of O15061 (212730_at) across 5392 perturbations tested by GENEVESTIGATOR:

bladder cancer study 1 / normal bladder tissue

Relative Expression (log2-ratio):-6.4717245
Number of Samples:3 / 3
Experimental bladder cancer study 1
Low grade superficial tumor samples.
Control normal bladder tissue
Normal bladder tissue.

bladder cancer study 3 / normal bladder tissue

Relative Expression (log2-ratio):-6.3308916
Number of Samples:3 / 3
Experimental bladder cancer study 3
High grade muscle invasive tumors.
Control normal bladder tissue
Normal bladder tissue.

basal cell carcinoma study 3 / normal epidermal keratinocytes

Relative Expression (log2-ratio):5.6493855
Number of Samples:4 / 2
Experimental basal cell carcinoma study 3
Primary tumor tissue from the eyelid of patients with basal cell carcinoma (BCC).
Control normal epidermal keratinocytes
Normal human epidermal keratinocytes (NHEK) (Kurabo Ind., Ltd., Osaka, Japan) cultured in HuMedia-KB2 medium at 37?C in humidified air containing 5% CO2.

glioma study 16 (LN-18) / normal astrocyte sample

Relative Expression (log2-ratio):-5.0996504
Number of Samples:2 / 3
Experimental glioma study 16 (LN-18)
Human glioma cell line LN018 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37C and 5% CO2.
Control normal astrocyte sample
Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations.

bladder cancer study 2 / normal bladder tissue

Relative Expression (log2-ratio):-4.6619043
Number of Samples:3 / 3
Experimental bladder cancer study 2
High grade superficial tumors with an unclear clinical behavior.
Control normal bladder tissue
Normal bladder tissue.

breast cancer study 5 / normal mammary gland tissue

Relative Expression (log2-ratio):-4.4173803
Number of Samples:20 / 7
Experimental breast cancer study 5
Breast non-BLC (sporadic basal-like cancer) tumor samples.
Control normal mammary gland tissue
Normal breast tissue samples.

prostate cancer study 1 (meta.) / benign prostate tissue

Relative Expression (log2-ratio):-4.0133047
Number of Samples:6 / 6
Experimental prostate cancer study 1 (meta.)
Metastatic prostate cancer samples.
Control benign prostate tissue
Benign prostate samples.

hair follicle keratinocyte study 1 (CD200-/CD49+) / hair follicle keratinocyte study 1 (CD200+/CD49+)

Relative Expression (log2-ratio):-3.9047499
Number of Samples:3 / 3
Experimental hair follicle keratinocyte study 1 (CD200-/CD49+)
Primary hair follicle keratinocytes sample negative for CD200 and positive for CD49.
Control hair follicle keratinocyte study 1 (CD200+/CD49+)
Primary hair follicle keratinocytes sample positive for CD200 and CD49.

glioma study 17 (small cell glioblastoma; A2B5+) / non-tumor oligodendrocyte progenitor cell sample (cortex)

Relative Expression (log2-ratio):-3.8948727
Number of Samples:2 / 3
Experimental glioma study 17 (small cell glioblastoma; A2B5+)
Oligodendrocyte progenitor cells (OPC) isolated from high grade small cell glioblastoma (grade IV). OPC were isolated using magnetic-activated cell sorting (MACS) with antibodies against A2B5 antigen. Patients were 56 ? 3 years old males.
Control non-tumor oligodendrocyte progenitor cell sample (cortex)
Oligodendrocyte progenitor cells (OPC) isolated from cortical tissue, which was obtained from patients with epilepsy, but without any manifested brain cancer. OPC were isolated using magnetic-activated cell sorting (MACS) with antibodies against A2B5 antigen.

glioma study 17 (glioblastoma; A2B5+) / non-tumor oligodendrocyte progenitor cell sample (cortex)

Relative Expression (log2-ratio):-3.7970343
Number of Samples:3 / 3
Experimental glioma study 17 (glioblastoma; A2B5+)
Oligodendrocyte progenitor cells (OPC) isolated from high grade glioblastoma (grade IV). OPC were isolated using magnetic-activated cell sorting (MACS) with antibodies against A2B5 antigen. Patients were 66 ? 5 years old males.
Control non-tumor oligodendrocyte progenitor cell sample (cortex)
Oligodendrocyte progenitor cells (OPC) isolated from cortical tissue, which was obtained from patients with epilepsy, but without any manifested brain cancer. OPC were isolated using magnetic-activated cell sorting (MACS) with antibodies against A2B5 antigen.