TOP TEN perturbations for P06401 (Homo sapiens)

Organism: Homo sapiens
Gene: P06401
Selected probe(set): 228554_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of P06401 (228554_at) across 5610 perturbations tested by GENEVESTIGATOR:

ovarian tumor study 17 / normal ovarian surface epithelial cell sample

Relative Expression (log2-ratio):-5.2543316
Number of Samples:9 / 10
Experimental ovarian tumor study 17
Human epithelial tumor cell samples from the ovary of patients with primary clear cell carcinoma. Samples were derived by laser capture microdissection (LCM).
Control normal ovarian surface epithelial cell sample
Human epithelial cell samples from histopathological normal and non-cancerous ovary tissue from donors with non-cancerous, benign gynecological diseases.

ovarian tumor study 16 / normal ovarian surface epithelial cell sample

Relative Expression (log2-ratio):-5.032673
Number of Samples:3 / 5
Experimental ovarian tumor study 16
Human epithelial tumor cell samples from the ovary of patients with papillary serous carcinoma. Samples were derived by laser capture microdissection (LCM).
Control normal ovarian surface epithelial cell sample
Human epithelial cell samples from histopathological normal and non-cancerous ovary tissue.

ovarian tumor study 28 (endometrioid carcinoma) / ovarian tumor study 28 (carcinosarcoma)

Relative Expression (log2-ratio):4.9195204
Number of Samples:6 / 2
Experimental ovarian tumor study 28 (endometrioid carcinoma)
Primary tumor tissue sample obtained from the ovary of female patients with endometrioid carcinoma.
Control ovarian tumor study 28 (carcinosarcoma)
Primary tumor tissue sample obtained from the ovary of female patients with carcinosarcoma.

breast cancer study 3 / normal mammary gland tissue

Relative Expression (log2-ratio):-4.734823
Number of Samples:17 / 7
Experimental breast cancer study 3
Breast basal tumor samples.
Control normal mammary gland tissue
Normal breast tissue samples.

rapidly progressive glomerulonephritis; ANCA-associated vasculitis study 5 (tubulointerstitium) / focal segmental glomerulosclerosis study 9 (glomerulus)

Relative Expression (log2-ratio):-4.4964886
Number of Samples:21 / 10
Experimental rapidly progressive glomerulonephritis; ANCA-associated vasculitis study 5 (tubulointerstitium)
Tubulointerstitium tissue sample obtained by microdissection from kidney biopsy, from patients suffering from rapidly progressive glomerulonephritis and antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. Donors were positive for ANCA-antibody. Biopsy samples were obtained from the European Renal cDNA Bank-Kroener-Fresenius biopsy bank. All biopsies were stratified by a reference pathologist.
Control focal segmental glomerulosclerosis study 9 (glomerulus)
Glomeruli tissue sample obtained by microdissection from kidney biopsy, from patients suffering from focal segmental glomerulosclerosis. Biopsy samples were obtained from the European Renal cDNA Bank-Kroener-Fresenius biopsy bank. All biopsies were stratified by a reference pathologist.

breast cancer study 4 / normal mammary gland tissue

Relative Expression (log2-ratio):-4.421665
Number of Samples:4 / 7
Experimental breast cancer study 4
Breast BRCA1-deficient tumor samples.
Control normal mammary gland tissue
Normal breast tissue samples.

breast cancer study 40 (metastase; ovary) / ovarian tumor study 28 (carcinosarcoma)

Relative Expression (log2-ratio):4.2575006
Number of Samples:44 / 2
Experimental breast cancer study 40 (metastase; ovary)
Metastatic tumor tissue obtained from the ovary of female patients with primary breast cancer.
Control ovarian tumor study 28 (carcinosarcoma)
Primary tumor tissue sample obtained from the ovary of female patients with carcinosarcoma.

SDF study 4 / untreated MDA Mb231 cell sample

Relative Expression (log2-ratio):4.247959
Number of Samples:3 / 6
Experimental SDF study 4
MDA Mb231 cells treated with 75nM stromal derived factor (SDF; Cxcl12) for 6h.
Control untreated MDA Mb231 cell sample
Untreated MDA Mb231 cells harvested after 6h.

ovarian tumor study 26 (serous carcinoma; metastase; peritoneum) / ovarian tumor study 26 (serous carcinoma; borderline; primary)

Relative Expression (log2-ratio):-4.0321674
Number of Samples:15 / 30
Experimental ovarian tumor study 26 (serous carcinoma; metastase; peritoneum)
Metastatic tumor tissue sample obtained from the peritoneum of female patients with primary serous cystadenocarcinoma of the ovary.
Control ovarian tumor study 26 (serous carcinoma; borderline; primary)
Ovarian tissue samples from female patients with primary serous cystadenoma with low malignant potential (borderline).

ovarian tumor study 27 (papillary serous cystadenocarcinoma; metastase) / ovarian tumor study 27 (papillary serous cystadenocarcinoma; bmp; primary)

Relative Expression (log2-ratio):-4.0320444
Number of Samples:53 / 18
Experimental ovarian tumor study 27 (papillary serous cystadenocarcinoma; metastase)
Metastatic tumor tissue samples obtained from different anatomical sites (colon, omentum, peritoneum and unstated sites) of female patients with primary papillary serous cystadenocarcinoma of the ovary.
Control ovarian tumor study 27 (papillary serous cystadenocarcinoma; bmp; primary)
Primary tumor tissue samples obtained from the ovary of female patients with papillary serous cystadenocarcinoma with borderline malignant potential (bmp).