TOP TEN perturbations for P12271 (Homo sapiens)

Organism: Homo sapiens
Gene: P12271
Selected probe(set): 206154_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of P12271 (206154_at) across 5217 perturbations tested by GENEVESTIGATOR:

retina pigment epithelium study 2 (fetal) / retina pigment epithelium study 1 (fetal)

Relative Expression (log2-ratio):-3.4957752
Number of Samples:12 / 6
Experimental retina pigment epithelium study 2 (fetal)
Human cultured fetal retina pigment epithelium samples obtained at gestation age between week 16-18.
Control retina pigment epithelium study 1 (fetal)
Human native fetal retina pigment epithelium samples obtained at gestation age between week 16-18.

RAF1 depletion study 1 / control vector transfected SW-480 cell sample

Relative Expression (log2-ratio):-2.644168
Number of Samples:6 / 6
Experimental RAF1 depletion study 1
RNAi-mediated gene knockdown of RAF1 in colorectal cancer cell line SW-480.
Control control vector transfected SW-480 cell sample
SW-480 colorectal cell line sample transduced with empty vector pLKO.

RAF1 depletion study 1 / mock transfected SW-480 cell sample

Relative Expression (log2-ratio):-2.6277447
Number of Samples:6 / 6
Experimental RAF1 depletion study 1
RNAi-mediated gene knockdown of RAF1 in colorectal cancer cell line SW-480.
Control mock transfected SW-480 cell sample
SW-480 colorectal cell line sample transduced with non-targeting pLKO_NonTarget vector.

NGFR depletion study 1 / control vector transfected SW-480 cell sample

Relative Expression (log2-ratio):-2.345273
Number of Samples:6 / 6
Experimental NGFR depletion study 1
RNAi-mediated gene knockdown of NGFR in colorectal cancer cell line SW-480.
Control control vector transfected SW-480 cell sample
SW-480 colorectal cell line sample transduced with empty vector pLKO.

NGFR depletion study 1 / mock transfected SW-480 cell sample

Relative Expression (log2-ratio):-2.3288498
Number of Samples:6 / 6
Experimental NGFR depletion study 1
RNAi-mediated gene knockdown of NGFR in colorectal cancer cell line SW-480.
Control mock transfected SW-480 cell sample
SW-480 colorectal cell line sample transduced with non-targeting pLKO_NonTarget vector.

HRAS depletion study 1 / control vector transfected SW-480 cell sample

Relative Expression (log2-ratio):-2.0522432
Number of Samples:6 / 6
Experimental HRAS depletion study 1
RNAi-mediated gene knockdown of HRAS in colorectal cancer cell line SW-480.
Control control vector transfected SW-480 cell sample
SW-480 colorectal cell line sample transduced with empty vector pLKO.

HRAS depletion study 1 / mock transfected SW-480 cell sample

Relative Expression (log2-ratio):-2.03582
Number of Samples:6 / 6
Experimental HRAS depletion study 1
RNAi-mediated gene knockdown of HRAS in colorectal cancer cell line SW-480.
Control mock transfected SW-480 cell sample
SW-480 colorectal cell line sample transduced with non-targeting pLKO_NonTarget vector.

RAF1 depletion study 1 / normal SW-480 cell sample

Relative Expression (log2-ratio):-1.8901768
Number of Samples:6 / 3
Experimental RAF1 depletion study 1
RNAi-mediated gene knockdown of RAF1 in colorectal cancer cell line SW-480.
Control normal SW-480 cell sample
Non-transduced SW-480 colorectal cell line sample.

MAPK1 depletion study 1 / control vector transfected SW-480 cell sample

Relative Expression (log2-ratio):-1.7938957
Number of Samples:6 / 6
Experimental MAPK1 depletion study 1
RNAi-mediated gene knockdown of MAPK1 in colorectal cancer cell line SW-480.
Control control vector transfected SW-480 cell sample
SW-480 colorectal cell line sample transduced with empty vector pLKO.

MAPK1 depletion study 1 / mock transfected SW-480 cell sample

Relative Expression (log2-ratio):-1.7774725
Number of Samples:6 / 6
Experimental MAPK1 depletion study 1
RNAi-mediated gene knockdown of MAPK1 in colorectal cancer cell line SW-480.
Control mock transfected SW-480 cell sample
SW-480 colorectal cell line sample transduced with non-targeting pLKO_NonTarget vector.